Results: 370

Mycophenolate mofetil as an immunomodulator in refractory noninfectious uveitis

Arq. bras. oftalmol; 79 (6), 2016
ABSTRACT Purpose: To evaluate the efficacy and tolerance of mycophenolate mofetil (MMF) for the treatment of noninfectious uveitis using the methods advocated by the Standardization of Uveitis Nomenclature (SUN) Working Group and to compare this with other studies of immunosuppression in ocular inflamma...

Targeted preemptive therapy according to perceived risk of CMV infection after kidney transplantation

Braz. j. infect. dis; 20 (6), 2016
ABSTRACT Background: The identification of the best strategy to manage cytomegalovirus infection is hampered by uncertainties regarding the risk/benefit ratios of universal prophylaxis versus preemptive therapy, the impact of indirect cytomegalovirus effects and the associated costs. This study investig...

Miopatías inflamatorias con evolución recidivante
Relapses in inflammatory myopathies

Medicina (B.Aires); 76 (6), 2016
La mayoría de los estudios de tratamiento de las miopatías inflamatorias son de corte y no permiten establecer su eficacia en largo plazo. En este trabajo, describimos el seguimiento de siete pacientes con miopatías inflamatorias, 5 polimiositis y 2 dermatomiositis. Determinamos su presentación, su s...

Enfermedad por citomegalovirus en pacientes receptores de trasplante de corazón en un centro de referencia nacional

Rev. chil. infectol; 33 (6), 2016
Introduction: Heart transplantation remains as the treatment of choice when the heart failure is refractory to the medical or surgical therapy. Therefore, cytomegalovirus disease is an important post-heart-transplant infectious complication. Aims: To describe the prevalence and clinical characteristics o...

Nefropatía por poliomavirus en un paciente inmunosuprimido por trasplante renal secundario a la enfermedad de arteritis de Takayasu

Infectio; 20 (4), 2016
La nefropatía por poliomavirus es una enfermedad que predomina en los pacientes con trasplante renal por el tratamiento inmunosupresor para manutención del injerto renal. La prevalencia actual de esta enfermedad oscila entre el 1 y el 14%. La sospecha de la enfermedad se da por la presencia de decoy ce...

Remote ischemic preconditioning and tacrolimus in the fetal small bowel transplant in mice

Acta cir. bras; 31 (10), 2016
ABSTRACT PURPOSE: To evaluate the effect of remote ischemic preconditioning (IPC-R) in the fetal small bowel transplantation model. METHODS: Two groups were constituted: The Isogenic transplant (ISO, C57BL/6 mice, n=24) and the allogenic transplant (ALO, BALB/c mice, n=24). In each group, the animals w...

Periorbital discoid lupus: a rare localization in a patient with systemic lupus erythematosus

An. bras. dermatol; 91 (5,supl.1), 2016
Abstract A 40-year-old female patient with a 5-year history of systemic lupus erythematosus was referred to our policlinic with complaints of erythema, atrophy, and telangiectasia on the upper eyelids for 8 months. No associated mucocutaneous lesion was present. Biopsy taken by our ophthalmology departme...

Therapies for crohn's disease: a clinical update

Arq. gastroenterol; 53 (3), 2016
ABSTRACT The main objectives of clinical therapy in Crohn's disease are clinical and endoscopic remission without the use of corticosteroids for long periods of time, prevention of hospitalization and surgery, and improvement of quality of life. The main limitation of drug therapy is the loss of response...

Pancitopenia inducida por azatioprina: Casos clínicos

Arch. argent. pediatr; 114 (4), 2016
La azatioprina es un fármaco inmunosupresor que ha demostrado efectividad en el tratamiento de la enfermedad inflamatoria intestinal. Su metabolito, la 6-mercaptopurina, es metaboliza-do a través de la tiopurina metiltransferasa. Los pacientes con baja actividad enzimática pueden presentar mayores efe...

Morfea o esclerodermia localizada juvenil: caso clínico

Rev. chil. pediatr; 87 (4), 2016
Introducción: La morfea o esclerodermia localizada juvenil (ELJ) es una enfermedad autoinmune, inflamatoria, crónica, lenta y progresiva del tejido conectivo, de causa desconocida, que afecta preferentemente la piel y los tejidos subyacentes. Objetivos: Comunicar un caso de esclerodermia localizada juv...