Results: 310

Improved reverse transcription-polymerase chain reaction assay for the detection of flaviviruses with semi-nested primers for discrimination between dengue virus serotypes and Zika virus

Mem. Inst. Oswaldo Cruz; 113 (5), 2018
BACKGROUND The genus Flavivirus includes a variety of medically important viruses, including dengue virus (DENV) and Zika virus (ZIKV), which are most prevalent in Brazil. Because the clinical profile of patients affected by different DENV serotypes or ZIKV may be similar, the development of new methods...

Searching for the best real-time RT-PCRs to detect Zika virus infections: the importance of comparing several protocols

Braz. j. med. biol. res; 51 (6), 2018
Clinical manifestations of Zika, dengue, and chikungunya virus infections are very similar, making it difficult to reach a diagnosis based only on clinical grounds. In addition, there is an intense cross-reactivity between antibodies directed to Zika virus and other flaviviruses, and an accurate Zika dia...

Potential role of dengue virus, chikungunya virus and Zika virus in neurological diseases

Mem. Inst. Oswaldo Cruz; 113 (11), 2018
This study showed that laboratory markers of recent infection by dengue, Zika or chikungunya arboviruses were detected in the biological samples of approximately one-third of patients with encephalitis, myelitis, encephalomyelitis or Guillain-Barré syndrome, in a surveillance programme in Piauí state, ...

Follow up of a robust meta-signature to identify Zika virus infection in Aedes aegypti: another brick in the wall

Mem. Inst. Oswaldo Cruz; 113 (6), 2018
The mosquito Aedes aegypti is the main vector of several arthropod-borne diseases that have global impacts. In a previous meta-analysis, our group identified a vector gene set containing 110 genes strongly associated with infections of dengue, West Nile and yellow fever viruses. Of these 110 genes, four ...

Imported case of Dengue virus 3 genotype I in Rio de Janeiro state, Brazil

Mem. Inst. Oswaldo Cruz; 113 (8), 2018
The dengue virus (DENV), of the genus Flavivirus (Flaviviridae), has four antigenically distinct serotypes, of which DENV-3 is classified into five genotypes. Here, we describe the detection of DENV-3 genotype I in sera of a Brazilian patient travelling from Singapore to Rio de Janeiro, Brazil, by using ...

Desafios e perspectivas de mães de crianças com microcefalia pelo vírus Zika
Challenges and perspectives of mothers of children with microcephaly due to Zika virus infection

Rev Rene (Online); 19 (), 2018
Objetivo: compreender desafios e perspectivas de mães de crianças com microcefalia pelo vírus Zika. Métodos: estudo qualitativo, realizado com doze mães de crianças com microcefalia pelo vírus Zika, em hospital público pediátrico. Dados coletados por meio de entrevista semiestruturada, os quais ...

Descrição dos casos de síndrome congênita associada à infecção pelo ZIKV no estado de São Paulo, no período 2015 a 2017

Epidemiol. serv. saúde; 27 (3), 2018
Objetivo: caracterizar os casos de síndrome congênita associada à infecção pelo ZIKV (SCZ) e outras etiologias infeciosas, residentes no estado de São Paulo, Brasil, no período de 30 de outubro de 2015 a 30 de junho de 2017. Métodos: estudo descritivo dos casos suspeitos de SCZ e outras etiolo...

Signifying Zika: heterogeneity in the representations of the virus by history of infection

Abstract: Despite having been broadly advertised by the mass media, many negative consequences of the Zika virus have been less significant than originally predicted. It is likely that after a few months from the epidemic's onset, personal experience with the virus has altered the person's way to deal wi...