Results: 436

Assessing endocrine and immune parameters in human immunodeficiency virus-infected patients before and after the immune reconstitution inflammatory syndrome

ABSTRACT Objective The present study compares immune and endocrine parameters between HIV-infected patients who underwent the Immune Reconstitution Inflammatory Syndrome (IRIS-P) during antiretroviral therapy (ART) and HIV-patients who did not undergo the syndrome (non-IRIS-P). Materials and methods Bl...

Soluble urokinase-type plasminogen activator receptor as a measure of treatment response in acute exacerbation of COPD

J. bras. pneumol; 44 (1), 2018
ABSTRACT Objective: To evaluate the value of soluble urokinase-type plasminogen activator receptor (suPAR) in the diagnosis of acute exacerbation of COPD (AECOPD) and in monitoring treatment response, analyzing the relationship between suPAR and fibrinogen in AECOPD. AECOPD leads to increased airway inf...

Advanced bone age as an indicator facilitates the diagnosis of precocious puberty

J. pediatr. (Rio J.); 94 (1), 2018
Abstract Objective: Diagnosis of central precocious puberty has always been challenging in clinical practice. As an important method in the diagnosis of central precocious puberty, luteinizing hormone-releasing hormone stimulation test is complex and time-consuming. In many cases, clinical traits are in...

Analyzing the neuropsychological characteristics and changes in serum markers of patients with chronic cerebral circulation insufficiency

Summary Objective: To investigate the neuropsychological characteristics and changes in CRP, S100B, MBP, HSP-7, and NSE in serum. Method: Sixty-six (66) patients treated in our hospital as CCCI group were chosen for our study, and 90 patients with depression were selected as the depression group. The p...

Sensibilidad diagnóstica de electroforesis de proteínas y cadenas livianas libres séricas en gammapatías monoclonales

Rev. méd. Chile; 146 (1), 2018
Background: International guidelines suggest a screening panel for monoclonal gammopathies that contains serum protein electrophoresis (SPE), free light chain (FLC) measurements and immunofixation. This combination provides the possibility of a timely accurate diagnosis. Aim: To evaluate the sensibility...

Sensitive Troponin I Assay in Patients with Chest Pain - Association with Significant Coronary Lesions with or Without Renal Failure

Arq. bras. cardiol; 110 (1), 2018
Abstract Introduction: Despite having higher sensitivity as compared to conventional troponins, sensitive troponins have lower specificity, mainly in patients with renal failure. Objective: Study aimed at assessing the sensitive troponin I levels in patients with chest pain, and relating them to the ex...

Polimorfismos de nucleotí­deo único associados à adiposidade corporal e ao metabolismo lipí­dico em indiví­duos adultos participantes do estudo de base populacional (ISA-Capital)

Introdução: no contexto das doenças crônicas não transmissíveis (DCNT), vários estudos associam a presença de determinados polimorfismos de nucleotídeo único (SNP) ao risco de desfechos metabólicos, como a obesidade e a dislipidemia. Objetivo: avaliar a presença de SNP associados à adiposida...

Accuracy of heparin binding protein: as a new marker in prediction of acute bacterial meningitis

Braz. j. microbiol; 49 (supl.1), 2018
ABSTRACT Background: Cerebrospinal fluid bacterial culture is the gold-standard for confirmation of acute bacterial meningitis, but many cases are not culture confirmed. Antibiotics reduce the chance of a microbiological diagnosis. Objective to evaluate efficacy of Heparin-binding protein in diagnosis o...

Oxidized and electronegative low-density lipoprotein as potential biomarkers of cardiovascular risk in obese adolescents

Clinics; 73 (), 2018
OBJECTIVES: To evaluate biomarkers associated with early cardiometabolic risk in obese adolescents. METHODS: This cross-sectional study included 137 adolescents of both sexes aged 10 to 19 years divided into a normal weight group (NW) (n=69) and an obese group (OB) (n=68). RESULTS: As expected, obesity...

Rastreo de hipercolesterolemia en niños y adolescentes
Lipid screening in childhood and adolescence