Among the neurodegenerative disorders, Parkinson disease (PD) is ranked as second most common. The pathological hallmark is selective degeneration of the dopaminergic neurons in the nigro-striatal regions of brain with appearance of the Lewy bodies. Present study explores the neuro-protective potential o...
Enfermedad de Parkinson/tratamiento farmacológico,
Modelos Animales de Enfermedad,
Ratas Sprague-Dawley,
Glucósidos/administración & dosificación,
Estilbenos/administración & dosificación,
Trastornos del Movimiento/prevención & control,
Fármacos Neuroprotectores,
Rotenona/toxicidad,
Inmunohistoquímica,
Enfermedad de Parkinson/patología,
Degeneración Nerviosa/prevención & control,
Dopamina
Brandão, Pedro;
Grippe, Talyta Cortez;
Modesto, Luiz Cláudio;
Ferreira, André Gustavo Fonseca;
Silva, Flávia Martins da;
Pereira, Flávio Faria;
Lobo, Marcelo Evangelista;
Allam, Nasser;
Freitas, Tiago da Silva;
Munhoz, Renato P.
ABSTRACT Parkinson's disease can be treated surgically in patients who present with motor complications such as fluctuations and dyskinesias, or medically-refractory disabling tremor. In this review, a group of specialists formulated suggestions for a preoperative evaluation protocol after reviewing the ...
ABSTRACT Neuropsychiatric disorders are common among patients with Parkinson's disease and may appear in any stage of the disease. However, these disorders often go undiagnosed and receive insufficient treatment. Observations in recent years have revealed that dopamine replacement therapy may lead to the...
La Enfermedad de Parkinson se inicia generalmente en las personas entre los 50 y 60 años, La mayoría de los pacientes de Parkinson se encuentran en situación de doble vulnerabilidad: vejez y discapacidad. El objetivo del tratamiento es reducir la velocidad de progresión de la enfermedad, controlar lo...
Enfermedad de Parkinson/complicaciones,
Trastornos Mentales/complicaciones,
Trastornos Mentales/tratamiento farmacológico,
Trastornos Psicóticos/complicaciones,
Trastornos Psicóticos/tratamiento farmacológico,
Intento de Suicidio,
Trastornos Mentales/diagnóstico,
Anamnesis,
Trastornos Psicóticos/diagnóstico,
Antipsicóticos/uso terapéutico,
Trastornos Mentales/clasificación
Background: Deep brain stimulation is an essential therapeutic tool in Parkinson's disease. Aim: To assess the results of a series of patients with Parkinson's disease treated with micro-electrode guided subthalamic nucleus stimulation. Material and Methods: Twenty patients with idiopathic Parkinson's ...
ABSTRACT There is great evidence linking neurotrophic factor (NF) dysfunction with Parkinson's disease (PD) pathophysiology. This study was conducted to evaluate plasma levels of NFs and their possible associations with clinical symptoms in PD. For this purpose, 40 PD patients and 25 controls were subjec...
ABSTRACT Objective: To translate and linguistically and culturally adapt to Brazilian Portuguese, and verify the reliability and validity of the Radboud Oral Motor Inventory for Parkinson's Disease (ROMP). Methods: The ROMP was translated and retranslated, and the instrument reliability was verified by...
Brasil,
Características Culturales,
Trastornos de Deglución/diagnóstico,
Trastornos de Deglución/etiología,
Escolaridad,
Enfermedad de Parkinson/complicaciones,
Reproducibilidad de los Resultados,
Trastornos del Habla/diagnóstico,
Trastornos del Habla/etiología,
Encuestas y Cuestionarios,
Traducciones
Introdução: A doença de Parkinson é a segunda doença neurodegenerativa mais prevalente na população mundial, com maior incidência nos idosos. A fadiga corresponde a um dos sintomas não motores mais frequentes na doença de Parkinson e prejudica a qualidade de vida desses pacie...
ABSTRACT Objective: To understand the daily lives of people with Parkinson's disease. Method: Qualitative research, using as methodological and theoretical referential the Grounded Theory and Symbolic Interactionism, respectively. The in-depth interview was conducted with 30 people with Parkinson's dis...
Adaptación Psicológica,
Enfermedad Crónica/psicología,
Enfermedad Crónica/terapia,
Costo de Enfermedad,
Teoría Fundamentada,
Entrevistas como Asunto,
Persona de Mediana Edad,
Enfermedad de Parkinson/complicaciones,
Enfermedad de Parkinson/psicología,
Enfermedad de Parkinson/terapia,
Investigación Cualitativa
