RESUMO A dobutamina é o inotrópico mais comumente utilizado em pacientes com choque séptico, com o objetivo de aumentar o débito cardíaco e corrigir a hipoperfusão. Embora alguns ensaios clínicos tenham demonstrado que a dobutamina pode melhorar a hemodinâmica sistêmica e regional, outras pesqui...
SUMMARY: Biomaterials are mostly polymers and are used in artificial organ production in contemporary medicine. They are prepared by the polymerization reaction of many monomers. There are many monomers used in biomaterial production. In this study, we investigated whether acrylamide (AAm), methacrylamid...
SUMMARY: The aim of the study was to evaluate the osteoprotective properties of RNA-containing drug Osteochondrin S on rats with experimental model of osteoporosis. Osteochondrin S contains yeast RNA and RNA of connective tissue of cattle. In order to model osteoporosis in rats bilateral ovariectomy was ...
SUMMARY: Diabetes mellitus is a common metabolic disease. There are many natural agents available to control and treat diabetes. Crab shell extract has antioxidant properties. The aim of present study was to investigate the effect of crab shell hydroalcoholic extract on blood glucose, liver enzymes, nitr...
SUMMARY: Special features of nanoparticles have resulted in their widespread use. Small molybdenum trioxide (MoO 3) nanoparticles can translocate from the entry portals into the circulatory and lymphatic systems and ultimately to body tissues and organs depending on their composition and size. In this re...
Molibdeno/administración & dosificación,
Oxígeno/administración & dosificación,
Nanopartículas,
Folículo Ovárico/efectos de los fármacos,
Ovario/efectos de los fármacos,
Ratas Wistar,
Estrógenos/sangre,
Progesterona/sangre,
Tamaño de los Órganos/efectos de los fármacos,
Gonadotropinas/sangre,
Ovario/ultraestructura,
Microscopía Electrónica
ABSTRACT Objective: Testicular torsion (TT) refers to rotation of the testis and twisting of the spermatic cord. TT results in ischemia-reperfusion (I/R) injury involving increased oxidative stress, inflammation and apoptosis, and can even lead to infertility. The aim of this study was to investigate th...
Abstract INTRODUCTION: Pseudomonas aeruginosa, an important pathogen globally, presents several resistance mechanisms. This study aimed to investigate the presence of bla GES in clinical isolates of Pseudomonas aeruginosa obtained from various clinical specimens from patients admitted to three different...
Antibacterianos/farmacología,
Secuencia de Bases,
Brasil,
Farmacorresistencia Bacteriana Múltiple/efectos de los fármacos,
Farmacorresistencia Bacteriana Múltiple/genética,
Pruebas de Sensibilidad Microbiana,
Reacción en Cadena de la Polimerasa,
Pseudomonas aeruginosa/efectos de los fármacos,
Pseudomonas aeruginosa/enzimología,
Pseudomonas aeruginosa/genética,
Análisis de Secuencia de ADN,
beta-Lactamasas/efectos de los fármacos,
beta-Lactamasas/genética
Abstract Background and objectives Dexmedetomidine (DEX) has demonstrated the preconditioning effect and shown protective effects against organize injury. In this study, using A549 (human alveolar epithelial cell) cell lines, we investigated whether DEX preconditioning protected against acute lung injur...
Abstract INTRODUCTION Incidence and antifungal susceptibility of Candida spp. from two teaching public hospitals are described. METHODS The minimum inhibitory concentrations of fluconazole, voriconazole, itraconazole, and amphotericin B were determined using Clinical Laboratory Standard Institute bro...
Anfotericina B/farmacología,
Antifúngicos/farmacología,
Brasil,
Candida/clasificación,
Candida/efectos de los fármacos,
Candida/genética,
Candidiasis/microbiología,
Farmacorresistencia Fúngica,
Fluconazol/farmacología,
Hospitales Públicos,
Itraconazol/farmacología,
Pruebas de Sensibilidad Microbiana,
Persona de Mediana Edad,
Voriconazol/farmacología
OBJECTIVES: To assess the impact of vasopressin on the microcirculation and to develop a predictive model to estimate the probability of microcirculatory recruitment in patients with septic shock. METHODS: This prospective interventional study included patients with septic shock receiving noradrenaline ...
Quimioterapia Combinada,
Microcirculación/efectos de los fármacos,
Norepinefrina/administración & dosificación,
Norepinefrina/farmacología,
Estudios Prospectivos,
Choque Séptico/tratamiento farmacológico,
Choque Séptico/fisiopatología,
Vasoconstrictores/administración & dosificación,
Vasoconstrictores/farmacología,
Vasopresinas/administración & dosificación,
Vasopresinas/farmacología
