Background: Latent tuberculosis has been associated with the persistence of dormant Mycobacterium tuberculosis in the organism of infected individuals, who are reservoirs of the bacilli and the source for spreading the disease in the community. New active anti-TB drugs exerting their metabolic action at ...
Abstract Introduction: The extensive use of antibiotics has led to the emergence of multi-resistant strains in some species of the genus Acinetobacter. Objective: To investigate the molecular characteristics of multidrug-resistant of Acinetobacter ssp. strains isolated from 52 patients collected betwee...
Infecciones por Acinetobacter/tratamiento farmacológico,
Acinetobacter/efectos de los fármacos,
Antibacterianos/farmacología,
beta-Lactamasas/genética,
Acinetobacter/clasificación,
Acinetobacter/genética,
Infecciones por Acinetobacter/epidemiología,
Infecciones por Acinetobacter/microbiología,
Colombia,
ADN Bacteriano/genética,
ADN Ribosómico/genética,
Pruebas Antimicrobianas de Difusión por Disco,
Farmacorresistencia Bacteriana Múltiple,
Unidades de Cuidados Intensivos,
Reacción en Cadena de la PolimerasaMétodos
La osteoporosis afecta al 6-7% de la población masculina. Es alta la proporción de pacientes con fracturas sin diagnóstico previo de esta enfermedad. La mortalidad luego de una fractura es mayor en hombres que en población femenina; a pesar de esto, la mayoría de los pacientes no reciben tratamiento...
Argentina,
Calcio/administración & dosificación,
Compuestos Organometálicos,
Conservadores de la Densidad Ósea/uso terapéutico,
Densidad Ósea/efectos de los fármacos,
Enfermedades Óseas Metabólicas/metabolismo,
Enfermedades Óseas Metabólicas/sangre,
Enfermedades Óseas Metabólicas/tratamiento farmacológico,
Estroncio/administración & dosificación,
Estroncio/química,
Estudios Retrospectivos,
Factores de Riesgo,
Factores Sexuales,
Fracturas Osteoporóticas,
Hipogonadismo/complicaciones,
Índice de Masa Corporal,
Osteoporosis/diagnóstico,
Osteoporosis/tratamiento farmacológico,
Testosterona/uso terapéutico,
Tiofenos,
Vitamina D/administración & dosificación
ABSTRACT High toxicity of the preservatives most frequently used in wood treatment and the resulting risks of handling pose a threat to small producers and to the environment. In an attempt to mitigate these problems, the present study was conducted with the objective of evaluating the preservative effec...
ABSTRACT Evaluate the effect of the extract of Ginkgo biloba in the bone alkaline phosphatase, bone mineral density, in the mechanical properties of the tibia in rats with glucocorticoid-induced-osteoporosis. After osteoporosis induction, the rats were divided into five groups: Osteoporosis; EGb1 (28 mg/...
ABSTRACT Mentha pulegium (Lamiaceae) tea has been used as a traditional medicine; however, the modulatory effect of M. pulegium extracts on damage to human erythrocytes associated to t-butyl hydroperoxide (t-BHP) exposure remains to be investigated. Accordingly, we perform this study in order to test the...
ABSTRACT The purpose of this study was to determine the effects of the high consumption of sucrose on the levels of DNA damage in blood, hippocampus and bone marrow of rats. Male Wistar rats were treated for 4 months with sucrose (10% for 60 initial days and 34% for the following 60 days) in drinking wat...
Médula Ósea/efectos de los fármacos,
Médula Ósea/patología,
Ensayo Cometa,
Daño del ADN,
Diabetes Mellitus Tipo 2/complicaciones,
Sacarosa en la Dieta/efectos adversos,
Modelos Animales de Enfermedad,
Hipocampo/efectos de los fármacos,
Hipocampo/patología,
Pruebas de Micronúcleos,
Ratas Wistar
ABSTRACT Casearia genus (Salicaceae) is found in sub-tropical and tropical regions of the world and comprises about 160-200 species. It is a medicinal plant used in South America, also known as "guaçatonga", "erva-de-tiú", "cafezinho-do-mato". In Brazil, there are about 48 species and 12 are registered...
ESTEVAM, ELISÂNGELA B B;
DEUS, ISABELLA P B DE;
SILVA, VANESSA P DA;
SILVA, ELIZABETH A J DA;
ALVES, CASSIA C F;
ALVES, JOSÉ MILTON;
CAZAL, CRISTIANE M;
MAGALHÃES, LIZANDRA G;
PAGOTTI, MARIANA C;
ESPERANDIM, VIVIANE R;
SOUZA, ALEX F;
MIRANDA, MAYKER L D.
ABSTRACT Leishmaniasis and trypanosomiasis are globally widespread parasitic diseases which have been responsible for high mortality rates. Since drugs available for their treatment are highly hepatotoxic, nephrotoxic and cardiotoxic, adherence to therapy has been affected. Thus, the search for new, more...
ABSTRACT 6-Gingerol is the major active constituent of ginger. In the current study, we aimed to investigate the mechanisms underlying the effects of 6-Gingerol on hair growth. Mice were randomly divided into five groups; after hair depilation (day 0), mice were treated with saline, or different concentr...
Catecoles/farmacología,
Inducción Enzimática,
Alcoholes Grasos/farmacología,
Factor 7 de Crecimiento de Fibroblastos/biosíntesis,
Folículo Piloso/efectos de los fármacos,
Folículo Piloso/patología,
Factor I del Crecimiento Similar a la Insulina/biosíntesis,
Metaloproteinasa 2 de la Matriz/biosíntesis,
Metaloproteinasa 9 de la Matriz/biosíntesis,
Ratones Endogámicos C57BL,
Extractos Vegetales/farmacología,
Distribución Aleatoria,
Factor de Crecimiento Transformador beta/biosíntesis,
Factor A de Crecimiento Endotelial Vascular/biosíntesis
