ABSTRACT BACKGROUND: Aging is a complex process marked by alterations on gut functioning and physiology, accompanied by an increase on the inflammatory status, leading to a scenario called "inflammaging". OBJECTIVE: To evaluate the effects of a synbiotic substance on systemic inflammation, gut functi...
The potential inhibitory effect of the insulin mimicking agent, vanadium on type 2 diabetes mellitus (T2DM)induced alterations to the aorta ultrastructure associated with the suppression of dyslipedima and biomarkers of inflammation has not been investigated before. Therefore, we tested whether vanadium ...
Vanadio/administración & dosificación,
Aorta/ultraestructura,
Aorta/efectos de los fármacos,
Diabetes Mellitus Tipo 2/complicaciones,
Enfermedades de la Aorta/etiología,
Dislipidemias/tratamiento farmacológico,
Vanadio/farmacología,
Inflamación/tratamiento farmacológico,
Modelos Animales de Enfermedad,
Microscopía Electrónica de Transmisión,
Aorta/lesiones,
Ratas Sprague-Dawley
Lee, Eun;
Choi, Kil Yong;
Kang, Mi-Jin;
Lee, So-Yeon;
Yoon, Jisun;
Cho, Hyun-Ju;
Jung, Sungsu;
Lee, Si Hyeon;
Suh, Dong In;
Shin, Youn Ho;
Kim, Kyung Won;
Ahn, Kangmo;
Hong, Soo-Jong.
Abstract Objective Mold exposure in early life may be associated with development of atopic dermatitis; however, studies of this link are inconclusive and evidence for the underlying mechanism(s) is lacking. This study identified the association between the time of mold exposure and development of atopi...
Akarsu, Murat;
Hurşitoğlu, Mehmet;
Toprak, Zeki;
Yoldemir, Şengül Aydin;
Altun, Özgür;
Toprak, Ilkim Deniz;
Özcan, Mustafa;
Yürüyen, Gülden;
Uğurlukişi, Bilal;
Erdem, Mahmut Genco;
Kirna, Kerem;
Demir, Pinar;
Çapar, Gazi;
Arman, Yücel;
Tükek, Tufan.
ABSTRACT Objective Activated macrophages (M1-type macrophages) in adipose tissue secrete many proinflammatory cytokines that induce insulin resistance (IR). Oncostatin M (OSM), a member of the interleukin-6 (IL-6) family of Gp130 cytokines, plays an important role in a variety of biological functions, ...
Breder, J S C;
Pires, A L R;
Azevedo, F F;
Apolinário, P P;
Cantaruti, T;
Jiwani, S I;
Moraes, Â M;
Consonni, S R;
Araújo, E P;
Adams, G G;
Saad, M J A;
Lima, M H M.
The use of specially designed wound dressings could be an important alternative to facilitate the healing process of wounds in the hyperglycemic state. Biocompatible dressings combining chitosan and alginate can speed up wound healing by modulating the inflammatory phase, stimulating fibroblast prolifera...
Alginatos/administración & dosificación,
Vendajes,
Materiales Biocompatibles/administración & dosificación,
Biomarcadores/sangre,
Proliferación Celular/efectos de los fármacos,
Quitosano/administración & dosificación,
Colágeno/efectos de los fármacos,
Diabetes Mellitus Experimental/fisiopatología,
Inflamación/prevención & control,
Ratones Endogámicos C57BL,
Factores de Tiempo,
Cicatrización de Heridas/efectos de los fármacos
Abstract Background: The emergence of coronary heart disease is increased with menopause, physical inactivity and with dyslipidemia. Physical training is known to promote the improvement of cardiovascular functions. Objective: To investigate the effects of aerobic physical training on the left ventricl...
Colágeno Tipo I/metabolismo,
Colágeno Tipo III/metabolismo,
Inmunohistoquímica,
Inflamación/fisiopatología,
Metaloproteinasa 2 de la Matriz/metabolismo,
Metaloproteinasa 9 de la Matriz/metabolismo,
Ratones Noqueados,
Modelos Animales,
Miocardio/metabolismo,
Ovariectomía,
Estrés Oxidativo/fisiología,
Condicionamiento Físico Animal/fisiología
Abstract Background: People living with HIV are at increased risk of cardiovascular disease and carotid thickness, due to the inflammation caused by the virus, the antiretroviral therapy, and other risk factors. However, few studies have observed the occurrence of cardiovascular diseases and carotid thi...
Antirretrovirales/administración & dosificación,
Terapia Antirretroviral Altamente Activa,
Biomarcadores/sangre,
Enfermedades Cardiovasculares/sangre,
Grosor Intima-Media Carotídeo,
Estudios Transversales,
Infecciones por VIH/sangre,
Infecciones por VIH/complicaciones,
Infecciones por VIH/tratamiento farmacológico,
Inflamación/sangre,
Carga Viral
Antecedentes: la colecistectomía laparoscópica es uno de los procedimientos quirúrgicos más frecuentemente realizados. Las diferencias en la anatomía y en el grado de inflamación vesicular suelen causar dificultades técnicas intraoperatorias. Objetivo: determinar el valor de la proteína C reactiv...
