Marchi, Juliana Pelissari;
Lívero, Francislaine Aparecida dos Reis;
Soare, Andreia Assuncao;
da Silva, Glacy Jaqueline;
Soares, Ana Karina Vargas;
Giarolo, Camila Moreno;
Jacomassi, Ezilda;
de Souza, Lauro Mera;
Bartolucci, Wanessa de Campos;
Gazim, Zilda Cristiani;
Campos, Caio Franco de Araújo Almeida;
Goncalves, José Eduardo;
Araújo, Cintia de Souza Alferes;
Wietzikoski, Samantha;
Lovato, Evellyn Claudia Wietzikoski.
Epidemiological evidence indicates that plant antioxidants activity can treat or help to prevent the development of various diseases. One species with great potential as an antioxidant is Curcuma longa. However, different extraction techniquescan influence isolated chemical compounds. This study invest...
Curcuma/química,
Antioxidantes/farmacología,
Antioxidantes/química,
Suplementos Dietéticos,
Compuestos Fenólicos/análisis,
Radicales Libres,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Fitoterapia,
Cromatografía de Gases y Espectrometría de Masas,
Diarilheptanoides/química
Melastoma malabathricum (M. malabathricum) extracts have been reported to exert various pharmacological activities including antioxidants, anti-inflammatory and antiproliferative activities. The objective of the present study was to determine the anticarcinogenic activity of its methanol extract (MEMM)...
Melastomataceae/química,
Extractos Vegetales/administración & dosificación,
Anticarcinógenos/administración & dosificación,
Hojas de la Planta,
Metanol,
Neoplasias del Colon/tratamiento farmacológico,
Cromatografía Líquida de Alta Presión,
Ratas Sprague-Dawley,
Colon/patología,
Focos de Criptas Aberrantes,
Peso Corporal/efectos de los fármacos,
Tamaño de los Órganos/efectos de los fármacos,
Antioxidantes,
Compuestos Fenólicos,
Carcinogénesis/efectos de los fármacos
Escherichia coli is a pathogen associated with infections in piglets in the post-weaning phase, its pathogenicity is related to the animal's susceptibility to bacterial enterotoxins. The objective of the present study was to determine the EOs activity against E. colistrain, in the form planktonic and se...
Extractos Vegetales/farmacología,
Aceites Volátiles/farmacología,
Escherichia coli/efectos de los fármacos,
Diarrea/microbiología,
Antibacterianos/farmacología,
Pruebas de Sensibilidad Microbiana,
Biopelículas/efectos de los fármacos,
Escherichia coli/aislamiento & purificación,
Escherichia coli/citología,
Porcinos,
Cromatografía de Gases y Espectrometría de Masas,
Ionización de Llama,
Extractos Vegetales/química,
Aceites Volátiles/química,
Antibacterianos/química,
Ocimum basilicum,
Cymbopogon
Cancer is an abnormal and uncontrolled growth of cells that spreads through cell division. There are different types of medicines available to treat cancers, but no drug is found to be fully effective and safe for humans. The major problem involved in the cancer treatments is the toxicity of the establi...
Solanum nudum Dunal (Solanaceae) is most commonly known andused by the population of the colombian Pacific coast as an antimalarial treatment. This article study into optimization and quantitative analysis of compounds steroidal over time of development of this species when grown in vitro and wild. A n...
Abstract In the present study, the metabolite profiling of methanolic extract from aerial parts of Satureja khuzistanica Jamzad, as an endemic medicinal plant from Iran, was evaluated using HPLC-PDA-ESI. Then, the main compound from the extract was isolated and purified by using extensive chromatographic...
Abstract Essential oils from four Ocotea species collected in southern Brazil were evaluated for chemical composition using gas chromatography coupled with mass spectrometry. The primary compound identified in O. acutifolia essential oil was an unsaturated tetracyclic diterpene, phyllocladene (67.7%), f...
Dentre os subtipos de câncer de mama, o triplo negativo (TNBC) é o que apresenta as maiores taxas de mortalidade, sendo, portanto, considerado um enorme desafio para a clínica. O uso de moléculas como marcadores tumorais vem auxiliando o clínico no diagnóstico, no prognóstico e, até mesmo, no tra...
The solar ultraviolet (UV) radiation that reaches the Earth is composed of 95% of UVA (320 to 400 nm) and 5% of UVB (280 to 320 nm) radiation. UVB is carcinogenic, generating potentially mutagenic DNA lesions. The solar UVA radiation also causes DNA damage, but this fact does not fully account for its bi...
Proteómica/clasificación,
Queratinocitos/química,
Rayos Ultravioleta/efectos adversos,
Antioxidantes/efectos adversos,
Células Epiteliales/clasificación,
Células HaCaT/clasificación,
ADN,
Dosis de Radiación,
Espectrometría de Masas/métodos,
Genotoxicidad/efectos adversos,
Piel
O neuroblastoma é um tumor sólido muito comum em crianças. O estágio mais avançado da doença é altamente agressivo e invasivo, além de pouco responsivo à terapia, que é limitada por mecanismos de resistência e reincidência relacionados à metástase. Muitos estudos tem sido feitos para identi...
