Results: 428

Papel dos receptores purinérgicos em modelo animal de doença de Parkinson

A Doença de Parkinson é uma doença altamente incapacitante e de grande prevalência. Pouco se sabe sobre sua etiologia e os tratamentos atuais consistem na diminuição dos sintomas, uma vez que ainda não foi encontrada uma maneira de reverter o déficit de neurônios dopaminérgicos observados nos p...

Papel do receptor B2 de cininas na terapia da neurodegeneração dopaminérgica em modelo animal

A Doença de Parkinson (DP) é um distúrbio neurodegenerativo, caracterizada em parte pela perda de neurônios dopaminérgicos da via nigroestriatal, originada na substância negra com projeções para o estriado, causando vários déficits motores. Atualmente, o tratamento mais utilizado é a administr...

The effects of functional training and stationary cycling on respiratory function of elderly with Parkinson disease: a pilot study

Abstract Introduction: Respiratory function changes in patients with Parkinson's disease (PD) contribute to aspiration pneumonia, the main cause of mortality in PD population. Objective: To compare the effects of functional training and cycle exercise in respiratory function of elderly with PD. Method...

Using the spirometry to indicate respiratory exercises for elderly with Parkinson's disease

Abstract Introduction: Respiratory dysfunction is the main cause of death in Parkinson's disease (PD) patients and bronchoaspiration pneumonia is the most common clinical respiratory complication. Objective: To assess respiratory function of elderly with PD in mild to moderate phase of the disease. Me...

Effects of virtual rehabilitation on cognition and quality of life of patients with Parkinson's disease

Abstract Introduction: Parkinson's disease causes progressive decline of motor and cognitive functions leading to a decrease in the independence and quality of life of people affected. Training through virtual reality is proving effective, as it promotes cognitive and motor stimuli, which can be benefi...

¿Es efectivo el tratamiento con células madre en la enfermedad de Parkinson?

Medwave; 18 (5), 2018
Resumen INTRODUCCIÓN: Muchos pacientes con enfermedad de Parkinson tienen una respuesta limitada con el tratamiento farmacológico convencional. Se ha postulado el uso de células madre como una alternativa, aunque su efectividad sigue siendo un tema de controversia. MÉTODOS: Para responder esta pregu...

Efficacy of neurofunctional versus resistance training in improving gait and quality of life among patients with Parkinson's disease: a randomized clinical trial

Motriz (Online); 24 (2), 2018
Abstract AIMS to compare the efficacy of neurofunctional training versus resistance training in improving gait and quality of life among patients with PD METHODS This randomized controlled trial included 40 participants randomly assigned to two groups through random number table generator: resistance t...

Impact of levodopa treatment in the voice pattern of Parkinson's disease patients: a systematic review and meta-analysis

CoDAS; 30 (5), 2018
Abstract Purpose Investigate the association between levodopa therapy and vocal characteristics in Parkinson's disease patients. Search strategy Studies published at MEDLINE, LILACS, and SciELO, from 1960 to December 2016. A systematic review and meta-analysis was performed using the following keywor...