OBJECTIVES: The intrathecal route has not yet been thoroughly standardized and evaluated in an experimental model of spinal cord injury (SCI) in Wistar rats. The objective of this study was to standardize and evaluate the effect of intradural injection in this animal model. METHOD: The animals were divi...
The objective of this study was to examine the safety of multiple repeated percutaneous punctures of cisterna magna for collecting cerebrospinal fluid (CSF) and preliminarily determine the optimal time interval and volume at each collection. Sixty Wistar rats were randomly assigned to six groups: 10 d-0 ...
Hartmann, D D;
Martins, R P;
Silva, T C da;
Stefanello, S T;
Courtes, A A;
Gonçalves, D F;
Furtado, A B V;
Duarte, B S L;
Signori, L U;
Soares, F A A;
Puntel, G O.
The skin injury healing process involves the main phases of homoeostasis, inflammation, proliferation, and remodeling. The present study aimed to analyze the effects of low-level laser therapy (LLLT) on hematological dynamics, oxidative stress markers, and its relation with tissue healing following skin ...
Trevisan, C S C;
Garcia-Araújo, A S;
Duarte, A C G O;
Furino, V O;
Russo, T L;
Fujimoto, A;
Souza, H C D;
Jaenisch, R B;
Arena, R;
Borghi-Silva, A.
This study verified the effects of respiratory muscle training (RMT) on hemodynamics, heart rate (HR) variability, and muscle morphology in rats with streptozotocin-induced diabetes mellitus (DM). Thirty-six male Wistar rats were randomized into 4 groups and 34 completed the study: i) sham-sedentary (Sha...
OBJECTIVES: The current study compared the impact of pretreatment with melatonin and N-acetylcysteine (NAC) on the prevention of rat lung damage following intestinal ischemia-reperfusion (iIR). METHODS: Twenty-eight Wistar rats were subjected to intestinal ischemia induced by a 60 min occlusion of the s...
Nascimento, Jéssica Junia Aparecida Cardoso;
Machado, Alex Sander Dias;
Della-Santa, Giovanna Moura Lamas;
Fernandes, Danielle Cristina;
Ferreira, Marcílio Coelho;
Machado, Gustavo Augusto Pereira;
Chaves, Bruna Carolina Garcia;
Costa, Karine Beatriz;
Rocha-Vieira, Etel;
Oliveira, Murilo Xavier;
Gaiad, Thais Peixoto;
Santos, Ana Paula.
ABSTRACT Objective: To evaluate the effects of photobiomodulation therapy in redox status, angiogenesis marker - vascular endothelial growth factor - and in the functional recovery in denervated muscle. Methods: A total of 32 female Wistar rats underwent a crush injury and were randomly divided into fo...
ABSTRACT Objective To analyze whether passive inhalation of cigarette smoke causes morphological, structural, and functional changes in kidneys of rats. Methods Wistar rats, aged eight weeks, weighing on average 260g, were divided into Control Group and Smoking Group. Each group was subdivided into f...
Cabral, Diego Arthur Castro;
Campos, Fernanda Myllena Sousa;
Silva, Maria Clara Pinheiro da;
Medeiros, João Paulo do Vale;
Batista, Paula dos Santos;
Jardim, Giovanna Coutinho;
Machado, Jéssica Lígia Picanço;
Cabral, Leonardo Giovanni Castro;
Mello, Vanessa Joia de;
Hamoy, Moises.
ABSTRACT Objective: To describe electrocorticographic, electromyographic and electrocardiographic profiles to report the electrophysiological effects of caffeine in Wistar rats. Methods: Male adult Wistar rats weighing 230g to 250g were used. Rats were allocated to one of two groups, as follows: Group ...
Objetivo: Analizar cualitativamente la biocompatibilidad
y la capacidad osteogénica de dos selladores endodónticos
a base de silicato de calcio: el biocerámico Bio-C Sealer
(BIOc) y MTA Densell Sealer (MTAd).
Materiales y métodos: En la tibia izquierda de 30
ratas Wistar macho se implantó un tubo de...
Sarraipo, Vagner Schiavoni;
Lizarte Neto, Fermino Sanches;
Carvalho, Camila Albuquerque Mello de;
Silva, Jairo Pinheiro da;
Durand, Marina Toledo;
Schimming, Bruno Cezar;
Martinez, Marcelo;
Galli, Maria de Fátima Tazima Sorita;
Buono, Fabianna de Oliveira;
Tiezzi, Maria Fernanda Barbirato da Mata;
Novais, Paulo Cezar;
Gula, Isabella Stracieri;
Thomazini, José Antônio;
Fazan, Valeria Paula Sassoli;
Rodrigues, Andressa Romualdo;
Tirapelli, Daniela Pretti da Cunha;
Cirino, Mucio Luiz de Assis;
Molina, Carlos Augusto Fernandes;
Junior, Silvio Tucci;
Tirapelli, Luis Fernando.
SUMMARY: Previous studies from our group described the consequences of using ethanol on penile erection. Nevertheless, the molecular mechanisms surrounding microRNAs, apoptosis process and their relationship with erectile dysfunction associated with alcohol consumption are still poorly understood. The ob...
Alcoholismo/metabolismo,
Disfunción Eréctil/metabolismo,
Apoptosis,
MicroARNs/metabolismo,
Factor Inductor de la Apoptosis/metabolismo,
Pene/química,
Modelos Animales de Enfermedad,
Inmunohistoquímica,
Ratas Wistar,
MicroARNs/análisis,
Factor Inductor de la Apoptosis/análisis,
Alcoholismo/fisiopatología,
Disfunción Eréctil/fisiopatología,
Pene/fisiopatología,
Reacción en Cadena en Tiempo Real de la Polimerasa,
MicroARNs/genética,
Factor Inductor de la Apoptosis/genética
