SUMMARY: Herbal extracts used for treatment of diabetes has focused mostly on the hypoglycaemic and anti-oxidant property.There are no studies which focused on its effect on dendritic architecture of pyramidal neurons of hippocampus caused by diabetes. This study was taken up to explore the effect of adm...
Abstract Introduction: The 72 kDa heat shock protein, HSP72, located intracellularly provides cochlear cytoprotective and anti-inflammatory roles in the inner ear during stressful noise challenges. The expression of intracellular HSP72 (iHSP72) can be potentiated by alanyl-glutamine dipeptide supplement...
Serra, T. L;
Santos, F. E;
Coelho, M. P. R. C;
Silva, C. M. O;
Melo, F. G;
Souza, A. C. S;
Primo, J. V. C;
Rodrigues, D. S;
Gomez, M. V;
Glória, J. R;
Ocarino, N. M;
Serakides, R;
Melo, E. G.
O objetivo deste estudo foi avaliar o efeito da ω-conotoxina MVIIC e das células-tronco mesenquimais (CTM) de forma isolada e sua associação nos ratos submetidos ao trauma medular agudo (TMA). Trinta Rattus novergicus, linhagem Wistar, três meses de idade, foram distribuídos igualmente em cinco gru...
Abstract Background and objectives: Sugammadex is an alternative pharmacological drug capable of reversing neuromuscular blockades without the limitations that are presented by anticholinesterase drugs. Coagulation disorders that are related to treatment with sugammadex were reported. The exact mechanis...
Anestesia/métodos,
Anestésicos por Inhalación,
Coagulación Sanguínea/efectos de los fármacos,
Combinación de Medicamentos,
Fibrinógeno/análisis,
Isoflurano,
Bloqueo Neuromuscular,
Fármacos Neuromusculares no Despolarizantes/administración & dosificación,
Fármacos Neuromusculares no Despolarizantes/farmacología,
Tiempo de Tromboplastina Parcial,
Recuento de Plaquetas,
Tiempo de Protrombina,
Distribución Aleatoria,
Ratas Wistar,
Rocuronio/administración & dosificación,
Rocuronio/farmacología,
Sugammadex/administración & dosificación,
Sugammadex/farmacología
Abstract The purpose of this investigation was to evaluate the effects of lithium chloride (LiCl) on the socket healing of estrogen-deficient rats. Seventy-two rats were allocated into one of the following groups: Control, Ovariectomy and LiCl (150 mg/kg/2 every other day orally) + Ovariectomy. Animals r...
Abstract Objective: To investigate the cardiovascular effects produced by transthoracic application of low-intensity pulsed ultrasound therapy (LIPUST). Methods: Three-month-old male Wistar rats (± 300 g, N=16) were randomly allocated in two groups, namely SHAM (control group, faked procedures) and US...
Resumo Fundamento O modelo de hipertensão arterial pulmonar induzida por monocrotalina (MCT) é um dos mais reproduzidos atualmente, apresentando como limitação a ausência de lesões plexiformes, manifestações típicas da doença grave em humanos. Objetivo Avaliar a gravidade da arteriopatia pu...
Abstract Introduction: This study presents the effect of cypermethrin on the cochlear function in Wistar rats post-subchronic inhalation exposure. Worldwide several pesticides are described as causing health disorders. Cypermethrin is currently one of the most commonly used, however, little is known abo...
SUMMARY: Repeated stress is a risk factor for memory impairment and neurological abnormalities in both humans and animals. We sought to investigate the extent of (i) brain tissue injury; (ii) nitrosative and oxidative stress in brain tissue homogenates; (iii) apoptotic and survival biomarkers in brain ti...
Estrés Psicológico/complicaciones,
Enfermedad Crónica,
Daño Encefálico Crónico/patología,
Apoptosis,
Estrés Nitrosativo,
Estrés Oxidativo,
Modelos Animales de Enfermedad,
Ratas Wistar,
Depresión,
Lesiones Encefálicas/metabolismo,
Óxido Nítrico Sintasa/análisis,
Malondialdehído/análisis,
Superóxido Dismutasa/análisis,
Caspasa 3/análisis,
Proteínas Proto-Oncogénicas c-bcl-2,
Análisis de Varianza,
Conducta Animal,
Biomarcadores,
Corteza Cerebral
SUMMARY: The aim of this study was to evaluate the effects of stretching and therapeutic ultrasound (TUS) on desmin and laminin contents of rat muscle after contusion. Male Wistar rats (n = 35, 8-9 weeks of age, 271 ± 14g body weight) were divided into five groups: Control group (CG) (n= 03); Injured gr...
