Summary Objective: To investigate the changes in serum cardiac myosin light chain 1 (CMLC-1) levels in children with fulminant myocarditis (FM) during continuous blood purification (CBP), as well as to analyze its correlation with other laboratory indexes. Method: Twenty-four (24) children with FM who ...
Biomarcadores/sangre,
Forma MB de la Creatina-Quinasa/sangre,
Ensayo de Inmunoadsorción Enzimática,
Hemofiltración/métodos,
Miocarditis/sangre,
Miocarditis/terapia,
Mioglobina/sangre,
Cadenas Ligeras de Miosina/sangre,
Péptido Natriurético Encefálico/sangre,
Fragmentos de Péptidos/sangre,
Valores de Referencia,
Estadísticas no Paramétricas,
Factores de Tiempo,
Troponina/sangre
BACKGROUND There is a lack of straightforward tests for field application and known biomarkers for predicting leprosy progression in infected individuals. OBJECTIVE The aim was to analyse the response to infection by Mycobacterium leprae based on the reactivity of specific antigens: natural disacchari...
Objective: To investigate plasma concentrations of S100B (a calcium-binding protein derived primarily from the glia) and inflammatory cytokines in children with autism and the relationship between S100B and cytokine concentrations. Methods: Plasma levels of S100B, tumor necrosis factor alpha (TNF-α...
RESUMEN El objetivo del estudio fue determinar la frecuencia de marcadores de infección para hepatitis B, hepatitis C y conocer los factores asociados en los donantes de sangre. El estudio se realizó con datos del registro de donantes de un hospital público de Lima. De 28 263 sujetos analizados entre ...
Abstract Background: Little has been studied on heart rate and its relationship with metabolic disorders. Objective: To identify possible association between heart rate (HR) and metabolic disorders in children and adolescents. Methods: This cross-sectional study evaluated 2.098 subjects, aged between ...
Biomarcadores/sangre,
Presión Sanguínea/fisiología,
Estudios Transversales,
Índice Glucémico/fisiología,
Frecuencia Cardíaca/fisiología,
Lípidos/sangre,
Enfermedades Metabólicas/sangre,
Enfermedades Metabólicas/diagnóstico,
Enfermedades Metabólicas/fisiopatología,
Esfuerzo Físico/fisiología,
Descanso/fisiología,
Ácido Úrico/sangre
Céspedes, Nora;
Valencia, Angela;
Echeverry, Carlos Alberto;
Arce-Plata, Maria Isabel;
Colón, Cristóbal;
Castiñeiras, Daisy E;
Hurtado, Paula Margarita;
Cocho, Jose Angel;
Herrera, Sócrates;
Arévalo-Herrera, Myriam.
Abstract Introduction: Inborn errors of metabolism (IEM) represent an important public health problem due to current diagnosis and treatment limitations, poor life quality of affected patients, and consequent untimely child death. In contrast to classical methods, tandem mass spectrometry (MS/MS) has al...
Aminoácidos/Sangre,
Carnitina/análogos & derivados,
Heptanoatos/Sangre,
Errores Innatos del Metabolismo/diagnóstico,
Espectrometría de Masas en Tándem/Métodos,
Biomarcadores/Sangre,
Carnitina/Sangre,
Colombia,
Estudios Transversales,
Reacciones Falso Positivas,
Errores Innatos del Metabolismo/Sangre,
Valores de Referencia,
Sensibilidad y Especificidad
ABSTRACT Objective This study aimed to investigate the association of plasma TNF-α, IL-6, and lL-10 levels and cytokine gene polymorphisms [TNF-α (-308 G→A), IL-6 (-174 C→G) and IL-10 (-1082 A→G, -819 T→C and -592 A→C)] in type 2 diabetes mellitus (T2DM) and obes...
Biomarcadores/sangre,
Índice de Masa Corporal,
Estudios de Casos y Controles,
Estudios Transversales,
Diabetes Mellitus Tipo 2/sangre,
Diabetes Mellitus Tipo 2/genética,
Frecuencia de los Genes,
Genotipo,
Interleucina-10/sangre,
Interleucina-10/genética,
Interleucina-6/genética,
Obesidad/sangre,
Obesidad/genética,
Reacción en Cadena de la Polimerasa,
Polimorfismo Genético,
Factor de Necrosis Tumoral alfa/sangre,
Factor de Necrosis Tumoral alfa/genética
ABSTRACT Objective To report the results of initial investigation and after 5 years of patients with a suspicious clinical scenario for acromegaly, elevated IGF-1, and nadir GH during an oral glucose tolerance test (OGTT) > 0.4 µg/L but < 1 µg/L. Subjects and methods Seventeen patients who ha...
Acromegalia/sangre,
Adenoma/sangre,
Adenoma/diagnóstico por imagen,
Biomarcadores/sangre,
Estudios de Seguimiento,
Prueba de Tolerancia a la Glucosa,
Hormona de Crecimiento Humana/sangre,
Factor I del Crecimiento Similar a la Insulina/análisis,
Imagen por Resonancia Magnética,
Fenotipo,
Neoplasias Hipofisarias/sangre,
Neoplasias Hipofisarias/diagnóstico por imagen,
Factores de Tiempo
ABSTRACT Objective The aim of this study was to evaluate the use of prophylactic oral calcium after total thyroidectomy in the prevention of symptomatic hypocalcemia, and to develop a rational strategy of oral calcium supplementation following this type of surgery. Subjects and methods Prospective st...
ABSTRACT Objective To investigate serum nesfatin-1 levels at 24-28 weeks of pregnancy in women newly diagnosed with gestational diabetes and determine the association of nesfatin-1 with several metabolic parameters. Subjects and methods Forty women newly diagnosed with gestational diabetes at 24-28 w...
Biomarcadores/sangre,
Índice de Masa Corporal,
Proteínas de Unión al Calcio/sangre,
Estudios de Casos y Controles,
Estudios Transversales,
Proteínas de Unión al ADN/sangre,
Diabetes Gestacional/sangre,
Diabetes Gestacional/diagnóstico,
Ensayo de Inmunoadsorción Enzimática,
Ayuno/sangre,
Edad Gestacional,
Prueba de Tolerancia a la Glucosa,
Proteínas del Tejido Nervioso/sangre,
Nucleobindinas
