Results: 1018

Genomic detection of a virus lineage replacement event of dengue virus serotype 2 in Brazil, 2019

BACKGROUND Despite efforts to mitigate the impact of dengue virus (DENV) epidemics, the virus remains a public health problem in tropical and subtropical regions around the world. Most DENV cases in the Americas between January and July 2019 were reported in Brazil. São Paulo State in the southeast of B...

Burden of dengue in the State of Meta, Colombia (2010-2016)

Abstract: In Colombia, dengue is a disease of great impact due to its morbidity and mortality, however, studies on the effects of the economic burden at the local level are scarce. Therefore, our study sought to describe the economic burden of dengue epidemics between 2010 and 2016 in the State of Meta, ...

Dengue in northeastern Brazil: a spatial and temporal perspective

Abstract INTRODUCTION: The state of Ceará (Brazilian Northeast) has a high incidence of dengue. Therefore, we aimed to characterize the temporal patterns and spatial distribution of dengue cases in Ceará during 2001-2019. METHODS: A spatiotemporal ecological study was performed with secondary data....

Avaliação da qualidade metodológica de diretrizes de vigilância e manejo clínico de dengue e chikungunya

Resumo: A pesquisa objetivou avaliar a qualidade metodológica de diretrizes do Ministério da Saúde brasileiro, da Organização Pan-Americana da Saúde (OPAS) e da Organização Mundial da Saúde (OMS) sobre vigilância e manejo clínico de dengue e chikungunya. Trata-se de um estudo descritivo, no qu...

Características da epidemia de dengue em Pinhalzinho, Santa Catarina, 2015-2016

Epidemiol. serv. saúde; 29 (4), 2020
Objetivo: Descrever as características da epidemia da dengue em Pinhalzinho, Santa Catarina, Brasil, e investigar os efeitos das variáveis climáticas sobre a infestação pelo mosquito Aedes aegypti. Métodos: Estudo ecológico, com dados sobre casos de dengue, hospitalizações e óbitos pela doenç...

Dengue, Yellow Fever, Zika and Chikungunya epidemic arboviruses in Brazil: ultrastructural aspects

Mem. Inst. Oswaldo Cruz; 115 (), 2020
BACKGROUND The impact of arbovirus cocirculation in Brazil is unknown. Dengue virus (DENV) reinfection may result in more intense viraemia or immunopathology, leading to more severe disease. The Zika virus (ZIKV) epidemic in the Americas provided pathogenicity evidence that had not been previously obser...

Dengue diagnostics: serious inaccuracies are likely to occur if pre-analytical conditions are not strictly followed

Mem. Inst. Oswaldo Cruz; 115 (), 2020
BACKGROUND The heat-labile nature of Dengue virus (DENV) in serum samples must be considered when applying routine diagnostic tests to avoid issues that could impact the accuracy of test results with direct implications for case management and disease reporting. OBJECTIVES To check if pre-analytical v...

Genomic detection of a virus lineage replacement event of dengue virus serotype 2 in Brazil, 2019

Mem. Inst. Oswaldo Cruz; 115 (), 2020
BACKGROUND Despite efforts to mitigate the impact of dengue virus (DENV) epidemics, the virus remains a public health problem in tropical and subtropical regions around the world. Most DENV cases in the Americas between January and July 2019 were reported in Brazil. São Paulo State in the southeast of ...

Prevention and control of Aedes transmitted infections in the post-pandemic scenario of COVID-19: challenges and opportunities for the region of the Americas

Mem. Inst. Oswaldo Cruz; 115 (), 2020
The coronavirus disease of 2019 (COVID-19) pandemic challenges public health systems around the world. Tropical countries will face complex epidemiological scenarios involving the simultaneous transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with viruses transmitted by Aedes a...

Low risk of serological cross-reactivity between dengue and COVID-19

Mem. Inst. Oswaldo Cruz; 115 (), 2020
In the near future, the overlap of Coronavirus disease 2019 (COVID-19) and dengue epidemics is a concrete threat in tropical regions. Co-epidemics of COVID-19 and dengue could be an overwhelming challenge for health systems in low- and middle-income countries. In this work, we investigated potential sero...