Results: 444

Translation, cross-cultural adaptation, and reliability of the Understanding COPD questionnaire for use in Brazil

J. bras. pneumol; 44 (4), 2018
ABSTRACT Objective: To translate the Understanding COPD (UCOPD) questionnaire into Portuguese, adapt it for use in Brazil, and assess its reliability. Methods: The UCOPD questionnaire consists of two sections, designated section A and section B. Section A comprises 18 items divided into three domains: ...

Asma e DPOC: está na hora de mudar conceitos e o foco do tratamento

A asma e a doença pulmonar obstrutiva crônica (DPOC) compõem um grupo de doenças respiratórias obstrutivas crônicas nas quais as disfunções refletem múltiplos processos inflamatórios do trato respiratório. Os mecanismos patogenéticos envolvidos em ambas são influenciados por uma interação ...

Clasificación de EPOC GOLD 2018: ¿otra oportunidad perdida?
Classification of EPOC GOLD 2018: Another missed opportunity?

Rev. am. med. respir; 18 (2), 2018
Recientemente se ha publicado la actualización de las guías GOLD (Global Initiative for Chronic Obstructive Lung Disease) correspondiente al año 2018. Las guías son producto de un gran esfuerzo de expertos para actualizar, en base a la evidencia científica publicada en el año previo, toda la inform...

Características de enfermedad pulmonar obstructiva crónica por consumo de tabaco en pacientes de servicios de neumología de Lima y Callao

RESUMEN El objetivo del estudio fue describir las características clínicas de pacientes con enfermedad pulmonar obstructiva crónica (EPOC), atendidos en los servicios de Neumología de centros especializados de Lima y Callao. Se realizó un estudio transversal en 196 pacientes, con una mediana de edad...

The triad of obstructive sleep apnea syndrome, COPD, and obesity: sensitivity of sleep scales and respiratory questionnaires

J. bras. pneumol; 44 (3), 2018
ABSTRACT Objective: To investigate whether the presence of obstructive sleep apnea syndrome (OSAS) alters the perception of respiratory symptoms and quality of life in COPD patients, by using specific questionnaires, as well as to determine whether scales for assessing daytime sleepiness and for screeni...

Is the COPD Assessment Test sensitive for differentiating COPD patients from active smokers and nonsmokers without lung function impairment? A population-based study

J. bras. pneumol; 44 (3), 2018
ABSTRACT Objective: To assess COPD Assessment Test (CAT) scores in adults with and without COPD, as well as to compare the CAT scores for nonsmokers, former smokers, and smokers without COPD with those for patients with COPD. Methods: This was a cross-sectional population-based study (the Respira Flori...

Cambios en la puntuación del índice BODE en pacientes con enfermedad pulmonar obstructiva crónica antes y después de rehabilitación pulmonar

Resumen Introducción: la rehabilitación pulmonar ha sido avalada como herramienta de tratamiento en la enfermedad pulmonar obstructiva crónica (EPOC). Aunque existen varios programas en nuestro medio, son escasos los reportes que evalúen el impacto de estos. El índice BODE es una escala multidimen...

Variables clínicas y funcionales asociadas al riesgo de muerte en el seguimiento a largo plazo en pacientes con enfermedad pulmonar obstructiva crónica

Rev. méd. Chile; 146 (4), 2018
Background: Identifying risk factors for long-term mortality in patients with chronic obstructive pulmonary disease (COPD) could improve their clinical management. Aim: To examine the clinical variables associated to long-term mortality in a cohort of COPD patients. Patients and Methods: A clinical and...

Expressions of TOLL-like receptor 4 (TLR-4) and matrix metalloproteinase 9 (MMP-9)/Tissue inhibitor of metalloproteinase 1 (TIMP-1) in pulmonary blood vessels with chronic obstructive pulmonary diseases and their relationships with pulmonary vascular remodelling

SUMMARY OBJECTIVE: This study aims at investigating the expressions of TOLL-like receptor 4 (TLR-4) and matrix metalloproteinase 9 (MMP-9)/ tissue inhibitor of metalloproteinase 1 (TIMP-1) in pulmonary blood vessels with chronic obstructive pulmonary disease (COPD) and their relationships with pulmonary...

Association between multidrug resistance-1 C3435T gene polymorphism and right ventricular dysfunction in patients with chronic obstructive pulmonary disease: cross-sectional study

Säo Paulo med. j; 136 (2), 2018
ABSTRACT BACKGROUND: Right ventricular (RV) dysfunction may develop over the course of chronic obstructive pulmonary disease (COPD) and is an important predictor of morbidity and mortality. Polymorphism of the multidrug resistance-1 (MDR-1) gene has been correlated with worse clinical findings among pat...