Gastric cancer (GC) is the third most lethal type of cancer worldwide. Single nucleotide polymorphisms (SNPs) in regulatory sites or coding regions can modify the expression of genes involved in gastric carcinogenesis, as ERBB2, which encodes for the tyrosine-kinase receptor HER-2. The aim of this work w...
Although rare, CALM/AF10 is a chromosomal rearrangement found in immature T-cell acute lymphoblastic leukemia (T-ALL), acute myeloid leukemia, and mixed phenotype acute leukemia of T/myeloid lineages with poor prognosis. Moreover, this translocation is detected in 50% of T-ALL patients with gamma/delta T...
Enfermedad Aguda,
Proteína alfa Potenciadora de Unión a CCAAT/genética,
Citometría de Flujo,
Genotipo,
Haploinsuficiencia/genética,
Hematopoyesis/genética,
Leucemia Mieloide Aguda/genética,
Ratones Transgénicos,
Fenotipo,
Factores de Transcripción/genética,
Translocación Genética/genética
Abstract: Specific variants in genes that encode adipokines and their mRNA and protein expression were previously studied in type 2 diabetes mellitus (T2DM) and obesity, and similar studies have been performed for chronic periodontitis (CP). The aim of this case-control study was to investigate the possi...
Adipoquinas/sangre,
Adipoquinas/genética,
Análisis de Varianza,
Biomarcadores/sangre,
Estudios de Casos y Controles,
Periodontitis Crónica/sangre,
Periodontitis Crónica/genética,
Diabetes Mellitus Tipo 2/sangre,
Diabetes Mellitus Tipo 2/genética,
Variación Genética,
Genotipo,
Persona de Mediana Edad,
Polimorfismo de Nucleótido Simple,
Valores de Referencia,
Estadísticas no Paramétricas
El oomicete Phytophthora infestans (Mont) DeBary es el patógeno responsable de causar la enfermedad denominada comúnmente como tizón tardío. Dicho patógeno afecta cultivos de importancia económica para el país, entre ellos el tomate, cultivo en el cual puede generar pérdidas totales en la producc...
Abstract INTRODUCTION Mozambique is one of three countries with high prevalence of tuberculosis (TB), TB/human immunodeficiency virus coinfection, and multidrug-resistant TB. We aimed to describe Mycobacterium tuberculosis spoligotypes circulating among drug resistant (DR) strains from Beira, Mozambiqu...
Oliveira, Manoel Marques E;
Almeida-Paes, Rodrigo;
Corrêa-Moreira, Danielly;
Borba, Cintia de Moraes;
Menezes, Rodrigo Caldas;
Freitas, Dayvison Francis Saraiva;
do Valle, Antonio Carlos Francesconi;
Schubach, Armando de Oliveira;
Barros, Monica Bastos de Lima;
Nosanchuk, Joshua D;
Gutierrez-Galhardo, Maria Clara;
Zancopé-Oliveira, Rosely Maria.
BACKGROUND Sporotrichosis is a subcutaneous mycosis caused by dimorphic pathogenic fungi belonging to the Sporothrix genus. Pathogenic Sporothrix species typically produce melanin, which is known to be a virulence factor. OBJECTIVES The aim of this study was to perform phenotypic, genotypic, and virule...
Antifúngicos/farmacología,
Dermatoglifia del ADN,
Modelos Animales de Enfermedad,
Genotipo,
Ratones Endogámicos BALB C,
Pruebas de Sensibilidad Microbiana,
Fenotipo,
Reacción en Cadena de la Polimerasa,
Sporothrix/efectos de los fármacos,
Sporothrix/genética,
Sporothrix/patogenicidad,
Esporotricosis/patología,
Esporotricosis/virología,
Virulencia
Tauro, Laura B;
Cardoso, Cristiane W;
Souza, Raquel L;
Nascimento, Leile CJ;
Santos, Daniela R dos;
Campos, Gubio S;
Sardi, Silvia;
Reis, Olivete B dos;
Reis, Mitermayer G;
Kitron, Uriel;
Ribeiro, Guilherme S.
A localized Chikungunya virus (CHIKV; East/Central/South African genotype) outbreak (50 cases, 70% laboratory-confirmed; attack rate: 5.3 confirmed cases/100 people) occurred in a Salvador, Brazil neighborhood, between Apr-Jun/2017. Highly clustered cases in space and time, mostly along a single street, ...
Brasil/epidemiología,
Fiebre Chikungunya/diagnóstico,
Fiebre Chikungunya/epidemiología,
Fiebre Chikungunya/virología,
Virus Chikungunya/genética,
Virus Chikungunya/inmunología,
Brotes de Enfermedades/estadística & datos numéricos,
Ensayo de Inmunoadsorción Enzimática,
Genotipo,
Persona de Mediana Edad,
Filogenia,
Reacción en Cadena de la Polimerasa,
Estaciones del Año
BACKGROUND In recent years, South America has suffered the burden of continuous high impact outbreaks of dengue, chikungunya and Zika. Aedes aegypti is the main mosquito vector of these arboviruses and its control is the only solution to reduce transmission. OBJECTIVES In order to improve vector contr...
Aedes/efectos de los fármacos,
Aedes/genética,
Biodiversidad,
Brasil,
Guyana Francesa,
Genotipo,
Resistencia a los Insecticidas/efectos de los fármacos,
Resistencia a los Insecticidas/genética,
Mosquitos Vectores/efectos de los fármacos,
Mosquitos Vectores/genética,
Mutación/genética
Abstract Porphyromonas gingivalis is one of the most important Gram-negative anaerobe bacteria involved in the pathogenesis of periodontitis. P. gingivalis has an arsenal of specialized virulence factors that contribute to its pathogenicity. Among them, fimbriae play a role in the initial attachment and ...
ADN Bacteriano,
Proteínas Fimbrias/genética,
Proteínas Fimbrias/aislamiento & purificación,
Genotipo,
Persona de Mediana Edad,
Índice Periodontal,
Periodontitis/microbiología,
Periodontitis/patología,
Periodontitis/terapia,
Reacción en Cadena de la Polimerasa,
Porphyromonas gingivalis/genética,
Porphyromonas gingivalis/aislamiento & purificación,
Fumar/efectos adversos,
Estadísticas no Paramétricas,
Factores de Tiempo
The resistance of plants to pests is a feature of great importance for agriculture, as it reduces costs with insecticides and promotes increased yield resulting in higher profits. This work aimed to evaluate the feeding preference of the Spodoptera frugiperda caterpillar by different sorghum genotypes. T...
