Results: 1561

Pharmacological evaluation of the hydro-alcoholic extract of Campomanesia phaea fruits in rats

Braz. j. biol; 80 (3), 2020
Abstract Campomanesia phaea (Myrtaceae), popularly known as cambuci, is one of several species of plants producing comestible fruits, largely used in human nutrition. Despite its consumption and economic potential, limited scientific research is available on the Campomanesia, especially those related to ...

Suspensão oral de rutina interfere na hiperplasia hepática em ratos

Arq. gastroenterol; 57 (3), 2020
ABSTRACT BACKGROUND: Rutin is a flavonol glycoside that can be found in a wide variety of vegetables and has activity, anti-cancer, anti-inflammatory and anti-diabetic properties. OBJECTIVE: This study investigated the effect of rutin oral administration on Wistar rats submitted to hepatic hyperplasi...

Changes of tyrosine phosphorylation in liver and kidney of polycystic ovarian rats induced by letrozole

Int. j. morphol; 38 (4), 2020
Letrozole (Letro) is a drug commonly used for breast cancer treatment since it can decrease estrogen level. In experimental animal, the Letro has been used to induce the polycystic ovarian syndrome (PCOS) model. Tyrosine phosphorylation (TyrPho) is an essential process in various biological functions bot...

Antiulcerogenic effects of selected African nightshades (Solanum nigrum Linn. ) genotypes on the rat stomach: a morphologic and morphometric study

Int. j. morphol; 38 (4), 2020
Solanum nigrum (SLN), commonly known as African nightshade, is used as a vegetable as well as in the management and treatment of various ailments including gastric ulcers. We analyzed, both grossly and microscopically using H&E, Masson's trichrome and PSA staining methods, the protective effects of a...

Monosodium glutamate alters the function and morphology of the parotid gland in Sprague Dawley rats

Int. j. morphol; 38 (4), 2020
Monosodium glutamate (MSG) is a flavor enhancer widely used in the food industry, with obesogenic properties, in addition to causing alterations in the oral cavity. The aim of the study was to observe the morphofunctional changes in the parotid gland after the administration of MSG in rats. 18 newborn ma...

The role of vaccinium myrtillus in the prevention of renal injury in an experimental model of ruptured abdominal aortic aneurysm

Abstract Objective: To examine the biochemical and histopathological renal effects of ischemia/reperfusion (I/R) injury using a ruptured abdominal aortic aneurysm (RAAA) model in rats and to investigate the potential protective effects of whortleberry (Vaccinium myrtillus). Methods: Thirty-two male Spr...

Comparison of tru-cut biopsy and fine-needle aspiration cytology in an experimental alcoholic liver disease model

SUMMARY INTRODUCTION Liver biopsies such as tru-cut (sharp needle) and fine-needle aspiration cytology (FNAC) are the most commonly preferred techniques to detect the grade and stage of certain liver diseases. In this study, we aimed to compare the efficiency of USG-guided tru-cut biopsy and fine-needl...

Healing effects of natural latex serum 1% from Hevea brasiliensis in an experimental skin abrasion wound model

An. bras. dermatol; 95 (4), 2020
Abstract Background Dermabrasion is related with mechanical and surgical traumas on the skin; usually topical antiseptics and/or saline have been used for healing. Natural products for wound healing can also be used for abrasions, such as latex from Hevea brasiliensis. Objective This study aimed to eva...

Dieta Intermitente Atenua a Remodelação Cardíaca Causada pelo Exercício Físico

Arq. bras. cardiol; 115 (2), 2020
Resumo Fundamento A influência de intervenções não farmacológicas como restrição calórica e exercício físico sobre a saúde e prevenção de enfermidades cardíacas tem sido documentada em estudos clínicos e experimentais. Objetivo Analisar a influência da combinação entre dieta intermi...

Effects of chronic stretching on soleus muscle of Wistar female rats

Int. j. morphol; 38 (4), 2020
The purpose of this study was to evaluate the chronic effects of stretching exercise on soleus muscle histomorphology and histomorphometry of young and aged rats. Thirty-eight female rats were divided into young control group (YCG, n=10;274±50 g); young stretching group (YSG, n=8;274±12 g); aged contro...