Results: 57

Evaluation of 6-Gingerol and its modified analogues as therapeutic candidates against Schistosoma mansoni phosphofructokinase

The African most prevalent tropical disease after malaria is schistosomiasis and this disease in the developing countries is a massive socio-economic and public health burden. The disease also caused over 200,000 deaths. The development and design of new and novel antischistosomal drugs is now very impor...

Expansão da circulação do vírus Zika da África à América, 1947-2018: revisão da literatura

Epidemiol. serv. saúde; 28 (2), 2019
Objetivo: descrever as expansões temporal e geográfica da circulação do vírus Zika (ZIKV) em países e territórios, desde seu isolamento até 2018. Métodos: revisão não sistemática da literatura do período entre 1947 e 2018, utilizando a base MEDLINE e estimativas da Organização Mundial da ...

A Review of Traditional Vaccine-Preventable Diseases and the Potential Impact on the Otolaryngologist

Abstract Introduction A majority of otolaryngologists have not had direct experience with many vaccine-preventable diseases since the creation of national vaccination programs. Despite the elimination of endemic transmission of some of these diseases in the United States, outbreaks can occur anywhere a...

CYP1A1, CYP1B1, GSTM1 and GSTT1 genetic variants and breast cancer risk in Mexican women

Salud pública Méx; 59 (5), 2017
Abstract: Objective: To evaluate if variants in the genes CYP1A1 (T3801C and A4889G), CYP1B1 (G119T), GSTM1 (indel) and GSTT1 (indel) are associated with breast cancer (BC) among Mexican women. Materials and methods: 952 incident cases with histologically confirmed BC were matched by age (± 5 years)...

Enfermedad por el virus del Ébola en el Centro de Tratamiento Coyah
Ebola virus disease at the Coyah Treatment Center

Rev. cuba. med. mil; 46 (3), 2017
Introducción: la enfermedad por Ébola tiene elevada letalidad y no existe tratamiento efectivo. Es necesario su estudio y estar preparados para el enfrentamiento de futuras epidemias. Objetivo: describir la distribución espacio-temporal y relación con variables de persona, lugar y tiempo, de los paci...

Efficacy and safety of a four-drug fixed-dose combination regimen versus separate drugs for treatment of pulmonary tuberculosis: a systematic review and meta-analysis

Braz. j. microbiol; 48 (2), 2017
Abstract Introduction: Tuberculosis, particularly multi-drug-resistant tuberculosis, is a major cause of morbidity and mortality worldwide. To the best of our knowledge, however, no study to date has assessed the combined use of the four available drugs for tuberculosis treatment, which is an issue of g...

Long-wavelength sensitive opsin (LWS) gene variability in Neotropical cichlids (Teleostei: Cichlidae)

An. acad. bras. ciênc; 89 (1), 2017
ABSTRACT Cichlid fishes are an important group in evolutionary biology due to their fast speciation. This group depends widely of vision for feeding and reproduction. During the evolutionary process it plays a significant role in interspecific and intraspecific recognition and in its ecology. The molecul...

Lepra: doença, isolamento e segregação no contexto colonial em Moçambique

Resumo A partir de documentação produzida entre a primeira metade do século XIX e a primeira metade do século XX, prioritariamente relatórios médicos, o artigo aponta as concepções vigentes na comunidade médica colonial e entre as populações locais sobre a lepra, suas manifestações e seu enf...

Relações contemporâneas entre o envelhecer, a religião e cultura, sob a luz junguiana dentro da Mitologia Africana

Rev. Kairós; 19 (4), 2016
Este trabalho visa a proporcionar, para estudiosos da gerontologia, psicólogos, e profissionais das diversas áreas, uma análise do envelhecimento, da velhice, articulada à questão da religião e cultura, levando em conta os pressupostos da psicologia analítica de Carl Gustav Jung, da mitologia jung...