Intoxicação acidental por metadona em paciente pediátrico
BioSCI. (Curitiba, Online); 81 (1), 2023
Results: 183
The effects of magnesium sulfate added to epidurally administered local anesthetic on postoperative pain: a systematic review
Braz. J. Anesth. (Impr.); 73 (4), 2023
Abstract Background This study evaluated the efficacy of epidurally administered magnesium associated with local anesthetics on postoperative pain control. Methods The study protocol was registered in PROSPERO as CRD42021231910. Literature searches were conducted on Medline, Cochrane, EMBASE, CENTRAL, ...
Continuous flow Aza-Michael reaction for preparing the fast-acting synthetic opioid drug Remifentanil
Braz. J. Pharm. Sci. (Online); 59 (), 2023
Abstract Remifentanil is a modern fentanyl analogue with ultrashort-action granted by an esterase-labile methyl propanoate chain. Here, we present the development of a continuous flow methodology for the key N-alkylation step of remifentanil preparation in a biphasic, "slug-flow" regime. We screened para...
Comparison of ultrasound-guided thoracic erector spinae plane block versus paravertebral block for analgesia after pediatric cardiac surgery
Rev. chil. anest; 52 (2), 2023
BACKGROUND: In pediatric cardiac surgery, the use of multimodal analgesia, including a regional analgesic technique reduces opioid consumption and adverse effects. OBJECTIVE: This study aimed to compare the effect of the ultrasound-guided bilateral thoracic erector spinae plane block (ESPB) and paraverte...
Procedimientos Quirúrgicos Cardíacos/efectos adversos, Analgesia/métodos, Bloqueo Nervioso/métodos, Ultrasonografía Intervencional, Dolor Postoperatorio/prevención & control, Esternotomía, Músculos Paraespinales, Vértebras Torácicas, Método Doble Ciego, Estudios Prospectivos, Analgésicos Opioides/administración & dosificación, Fentanilo/administración & dosificación, Dimensión del Dolor, Extubación Traqueal, Dolor Postoperatorio/tratamiento farmacológico
Chronic non-cancer pain in adolescents: a narrative review
Braz. J. Anesth. (Impr.); 72 (5), 2022
Abstract Introduction Chronic pain is defined as a pain lasting more than 3-6 months. It is estimated that 25% of the pediatric population may experience some kind of pain in this context. Adolescence, corresponding to a particular period of development, seems to present the ideal territory for the appe...
Efficacy of opioids and non-opioid analgesics in the treatment of post procedure pain of burned patients: a narrative review
Braz. J. Anesth. (Impr.); 72 (5), 2022
Abstract Introduction Burns are a common trauma that cause acute severe pain in up to 80% of patients. The objective of this narrative review is to evaluate the efficacy of opioids, non-steroidal anti-inflammatory drugs, paracetamol, gabapentinoids, ketamine, and lidocaine in the treatment of acute pain...
Acetaminofén, Dolor Agudo/tratamiento farmacológico, Dolor Agudo/etiología, Analgésicos, Analgésicos no Narcóticos, Analgésicos Opioides/uso terapéutico, Antiinflamatorios no Esteroideos/uso terapéutico, Quemaduras/complicaciones, Fentanilo, Gabapentina, Ketamina/uso terapéutico, Lidocaína, Nalbufina/uso terapéutico, Dolor Asociado a Procedimientos Médicos, Ensayos Clínicos Controlados Aleatorios como Asunto
Comparison of three intraoperative analgesic strategies in laparoscopic bariatric surgery: a retrospective study of immediate postoperative outcomes
Braz. J. Anesth. (Impr.); 72 (5), 2022
Abstract Introduction and objectives Multimodal Analgesia (MMA) has shown promising results in postoperative outcomes across a broad spectrum of surgeries, including bariatric surgery. We compared the analgesic effect immediately after Laparoscopic Bariatric Surgery (LBS) of the combined effect of MMA a...
Effect of continuous intra-incisional bupivacaine on postoperative pain in non-traumatic spinal fixation surgeries: a randomized controlled trial
Braz. J. Anesth. (Impr.); 72 (5), 2022
Abstract Background Continuous injection of local anesthetics by using surgical wound catheters for postoperative pain relief has gained acceptance in recent years. However, whether this method can be alternatively used instead of systemic opioids in different surgical procedures has not yet been elucid...
Analgesic effect of continuous adductor canal block versus continuous femoral nerve block for knee arthroscopic surgery: a randomized trial
Braz. J. Anesth. (Impr.); 72 (5), 2022
Abstract Background and objectives Anterior cruciate ligament reconstruction (ACLR) is one of the most frequently performed orthopedic procedures. The ability to perform ACLR on an outpatient basis is largely dependent on an effective analgesic regimen. The aim of the study was to compare the analgesic ...
Etiopathogenesis of drug dependence: an explanatory synthesis from an epigenetic perspective
Medicina UPB; 41 (2), 2022
The use of substances with addictive potential is a relevant health problem. Scientific evidence suggests that the underlying mechanisms that regulate behavioral processes in addictions involve a complex interplay between genetic and environmental factors. Therefore, this narrative review aims to provide...