Results: 125

Conduta terapêutica em pacientes com doença pulmonar obstrutiva crônica: monoterapia ou terapia cominada?

Objetivo: Comparar a dupla terapia broncodilatadora com glicopirrônio mais indacaterol à monoterapia com glicopirrônio em pacientes portadores de doença pulmonar obstrutiva crônica. Métodos: Estudo clínico prospectivo, unicêntrico, controlado, cruzado, randomizado e duplo-cego realizado com 14...

Características clínicas e fatores associados à asma grave em Salvador, Brasil

J. bras. pneumol; 46 (3), 2020
RESUMO Objetivo Descrever características clínicas e identificar fatores associados a maior gravidade da asma, em uma amostra de pacientes acompanhados em um centro de referência em Salvador. Métodos Estudo transversal de 473 adultos, acompanhados regularmente no Programa para Controle da Asma na B...

Quality of life evaluation and associated factorsin asthmatic children and adolescents attended in a specialized outpatient clinic

ABSTRACT Objective: To evaluate the quality of life and its association with disease control, severity, allergic comorbidities and adherence to treatment in children and adolescents with asthma. Methods: A cross-sectional study that included children and adolescents aged seven to 17. The Paediatric Ast...

Legal demands of the tiotropium bromide for treatment of chronic obstructive pulmonary disease and their financial impact for the State of Paraná, Brazil

ABSTRACT Objective To analyze the legal demands of tiotropium bromide to treat chronic obstructive pulmonary disease. Methods We included secondary data from the pharmaceutical care management systems made available by the Paraná State Drug Center. Results Public interest civil action and ordinary...

Corticosteroides inhalados en pacientes con asma leve intermitente
Inhaled corticosteroids in mild intermittent asthma

Una joven de 23 años con asma leve intermitente se presenta a la consulta médica. Se plantea cuál es la mejor alternativa para su tratamiento: el uso de broncodilatadores de acción corta a demanda (SABA, por sus iniciales en inglés) o de broncodilatadores de acción rápida en asociación con cortic...

Bronchodilator test in extreme old age: Adverse effects of short-acting beta-2 adrenergic agonists with clinical repercussion and bronchodilator response

SUMMARY OBJECTIVE: To evaluate chronological age as a limiting factor to perform the bronchodilator test, determine significant adverse effects of short-acting beta 2 agonists with clinical repercussions, and assess bronchodilator response in extreme-old-age patients who undergo the spirometry test. ME...

Conclusiones finales del desarrollo clínico de la terapia doble de broncodilatadores de acción prolongada de una vez al día en combinación fija en EPOC
Final conclusions of the clinical development of double therapy of long-acting once-daily bronchodilators in a fixed combination in COPD

Rev. am. med. respir; 19 (3), 2019
Este año se publicó el último de los estudios clínicos FASE III pendientes de una de las tres combinaciones fijas de broncodilatadores de acción prolongada de una vez al día, anticolinérgicos (LAMA: long-acting muscarinic antagonist) asociada a agonistas β2 adrenérgicos (LABA: long-acting β2 ...

Broncodilatadores en pacientes con bronquiolitis
Bronchodilators for bronchiolitis

La bronquiolitis es una infección respiratoria aguda baja de causa viral, de aparición invernal, que es común en bebés de 0a 12 meses de edad. Conduce a que las vías respiratorias pequeñas se inflamen y se llenen de desechos, obstruyéndose.El bebé tiene una tos fuerte, secreción nasal, generalme...

Controversies and limitations in the diagnosis of chronic obstructive pulmonary disease

Rev. invest. clín; 71 (1), 2019
Abstract Chronic obstructive pulmonary disease (COPD) is a major cause of chronic morbidity and mortality worldwide. While the cut-off point to define airflow obstruction has been controversial, it is widely accepted that the spirometry test is vital, as well as performing it after using a bronchodilator...