Results: 53

Protocol of nursing care on zero day of the transplantation of hematopoetic stem cells: collective construction

ABSTRACT Objective: to construct a protocol of nursing care to the patient on day zero of hematopoietic stem cell transplantation. Method: a convergent care research was developed from August to December 2016 in a Bone Marrow Transplant Service. The participants were twenty-two nurses from this service...

CD47 expression is decreased in hematopoietic progenitor cells in patients with myelofibrosis

Braz. j. med. biol. res; 52 (1), 2019
Myelofibrosis (MF) is characterized by increased circulating hematopoietic progenitor cells (HPCs), abnormal cytokine levels, and the survival advantage of neoplastic progenitors over their normal counterparts, which leads to progressive disappearance of polyclonal hematopoiesis. CD47 is a surface glycop...

Detecção e manejo de disfunções cardíacas em pacientes com esclerose sistêmica tratados com altas doses de ciclofosfamida seguidas por transplante de células-tronco hematopoéticas

O transplante autólogo de células-tronco hematopoéticas (TACTH) é efetivo para o tratamento da esclerose sistêmica (ES), com controle do acometimento pulmonar, e melhora da fibrose cutânea, da qualidade de vida e aumento da sobrevida global, quando comparado a pacientes não transplantados. Neste t...

A participação da autofagia na regulação da célula-tronco hemopoética em camundongos knockouts para Atg7 e transglutaminase 2

A desnutrição é um dos principais problemas de saúde pública do mundo, que contribui significativamente para o aumento da morbidade e mortalidade. Estima-se um total de 815 milhões de pessoas subnutridas no mundo, e apesar da melhoria dos recursos alimentares o número de pessoas desnutridas ainda ...

Single-cell qPCR facilitates the optimization of hematopoietic differentiation in hPSCs/OP9 coculture system

Braz. j. med. biol. res; 51 (5), 2018
Human pluripotent stem cells (hPSCs)/OP9 coculture system is a widely used hematopoietic differentiation approach. The limited understanding of this process leads to its low efficiency. Thus, we used single-cell qPCR to reveal the gene expression profiles of individual CD34+ cells from different stages o...

Bone marrow stem cell applied in the canine veterinary clinics

Pesqui. vet. bras; 37 (10), 2017
Cell therapy represents an old therapeutic practice initiated with the transfusion of whole blood in different clinical situations. There is now a breakthrough in the study of multipotent stem cell therapy because of its functionality in regeneration of tissues, which promotes attention of the scientific...

Protocolo de cuidados de enfermagem no dia zero do transplante de células-tronco hematopoéticas

Objetivo: Construir um protocolo de cuidados de enfermagem para o dia zero do transplante de células-tronco hematopoéticas. Metodologia: Trata-se de uma Pesquisa Convergente Assistencial, realizada no Laboratório de Manipulação celular e Criobiologia e no Serviço de Transplante de Medula Óssea do ...

Nutritional status and hyperglycemia in the peritransplant period: a review of associations with parenteral nutrition and clinical outcomes

ABSTRACT Hematopoietic stem cell transplantation is an established treatment option for various hematological diseases. This therapy involves complex procedures and is associated with several systemic complications. Due to the toxic effects of the conditioning regimen used in allogeneic transplantations,...