Mechanisms and biomarker candidates in pterygium development
Arq. bras. oftalmol; 83 (3), 2020
Results: 143
Carnitine analysis in pterygium
Arq. bras. oftalmol; 83 (1), 2020
ABSTRACT Purpose: The aim of the present study was to measure the free carnitine and acylcarnitine levels in pterygium tissue and normal conjunctival tissue at the metabolomics level using tandem mass spectrometry. Methods: In this prospective, clinical randomized study, pterygium tissues and normal co...
Effects of antibiotics and antiseptics on conjunctival bacterial flora in patients undergoing intravitreal injections
Arq. bras. oftalmol; 82 (5), 2019
Extensive bulbar conjunctival Kaposi's sarcoma as initial symptom of human immunodeficiency virus
Arq. bras. oftalmol; 82 (5), 2019
ABSTRACT Here, we present a case in which extensive bulbar conjunctival Kaposi's sarcoma was the initial presentation of human immunodeficiency virus in a 36-year-old man. The patient had a 3-month history of recurrent self-limited inferior conjunctiva hyperemia in the right eye, and presented with a pai...
Expression of specificity protein 1 and collagen I in primary pterygial tissues
Arq. bras. oftalmol; 82 (5), 2019
ABSTRACT Purpose: To determine the expression profiles of the transcription factor specificity protein 1 and collagen I in primary pterygial and normal conjunctival tissues, and to explore the role of specificity protein 1 and collagen I in pterygial development. Methods: The pterygial tissues of 20 pa...
Topical cyclosporine A 0. 05% before and after surgery to prevent pterygium recurrence
Arq. bras. oftalmol; 82 (5), 2019
ABSTRACT Purpose: We evaluated the role of the conjunctival flap rotation technique using 5-fluorouracil and adjuvant therapy with topical cyclosporine A at 0.05% during short pre- and postoperative periods for the prevention of primary pterygium recurrence. Methods: In this prospective study, 76 patie...
Terapia Combinada, Conjuntiva/anomalías, Conjuntiva/cirugía, Enfermedades de la Córnea/tratamiento farmacológico, Ciclosporina/administración & dosificación, Fluorouracilo/uso terapéutico, Inmunosupresores/administración & dosificación, Soluciones Oftálmicas/administración & dosificación, Cuidados Posoperatorios, Cuidados Preoperatorios, Estudios Prospectivos, Pterigion/tratamiento farmacológico, Pterigion/prevención & control, Pterigion/cirugía, Recurrencia, Colgajos Quirúrgicos
Ocular findings in Fabry disease in Colombian patients
Biomédica (Bogotá); 39 (3), 2019
ABSTRACT Fabry disease is a rare X-linked disorder caused by an alpha-galactosidase enzyme deficiency, which leads to a progressive lysosomal glycosphingolipids accumulation, mainly globotriaosylceramide, in multiple organism tissues including the eye. This case series describes the first ophthalmologica...
Oftalmopatías/diagnóstico, Enfermedad de Fabry/complicaciones, Ambliopía/diagnóstico, Catarata/diagnóstico, Colombia, Conjuntiva/anomalías, Conjuntiva/irrigación sanguínea, Enfermedad de Fabry/genética, Heterocigoto, Aparato Lagrimal/anomalías, Errores de Refracción/diagnóstico, Vasos Retinianos/anomalías
Ocular surface evaluation in pediatric Hashimoto's thyroiditis without thyroid-associated ophthalmopathy
Arq. bras. oftalmol; 82 (4), 2019
ABSTRACT Purpose: We aimed to assess ocular surface characteristics in children with Hashimoto's thyroiditis without thyroid-associated ophthalmopathy and compare the results with those of healthy children. Methods: Twenty-two children with Hashimoto's thyroiditis (Group 1) and 20 healthy children with...
Estudios de Casos y Controles, Conjuntiva/patología, Síndromes de Ojo Seco/etiología, Síndromes de Ojo Seco/patología, Enfermedad de Hashimoto/complicaciones, Enfermedad de Hashimoto/patología, Enfermedad de Hashimoto/fisiopatología, Glándulas Tarsales/patología, Estudios Prospectivos, Valores de Referencia, Índice de Severidad de la Enfermedad, Encuestas y Cuestionarios, Lágrimas/fisiología
Effects of benzalkonium chloride and cyclosporine applied topically to rabbit conjunctiva: a histomorphometric study
Arq. bras. oftalmol; 82 (4), 2019
ABSTRACT Purpose: Chronic instillation of benzalkonium chloride, a preservative, has inflammatory effects on the ocular surface. However, addition of the anti-inflammatory agent cyclosporine to a therapeutic protocol may mitigate these effects. This study compared the toxic effects of a 0.1% benzalkoniu...
Inductores de la Angiogénesis/farmacología, Antiinflamatorios/farmacología, Compuestos de Benzalconio/efectos adversos, Conjuntiva/efectos de los fármacos, Conjuntiva/patología, Ciclosporina/farmacología, Células Caliciformes/efectos de los fármacos, Conservadores Farmacéuticos/efectos adversos, Sustancias Protectoras/farmacología, Distribución Aleatoria, Reproducibilidad de los Resultados, Factores de Tiempo, Resultado del Tratamiento
Brimonidine-induced unilateral ocular lichen planus: a case report
Arq. bras. oftalmol; 82 (3), 2019
ABSTRACT This report was written to describe a case of unilateral brimonidine-induced conjunctival lichen planus. Because the ophthalmic examination indicated chronic conjunctivitis or drug-induced pseudopemphigoid, the patient underwent thorough ophthalmic and systemic examinations, as well as conjuncti...
Antihipertensivos/efectos adversos, Biopsia, Tartrato de Brimonidina/efectos adversos, Conjuntiva/patología, Enfermedades de la Conjuntiva/inducido químicamente, Enfermedades de la Conjuntiva/tratamiento farmacológico, Enfermedades de la Conjuntiva/patología, Ciclosporina/uso terapéutico, Inmunosupresores/uso terapéutico, Liquen Plano/inducido químicamente, Liquen Plano/tratamiento farmacológico, Liquen Plano/patología