ABSTRACT Objective: To investigate the anti-hyperglycemic effects of Plathymenia reticulata hydroalcoholic extract and related changes in body weight, lipid profile and the pancreas. Methods: Diabetes was induced in 75 adult male Wistar rats via oral gavage of 65mg/Kg of streptozotocin. Rats were alloc...
Glucemia/análisis,
Peso Corporal/efectos de los fármacos,
Colesterol,
Diabetes Mellitus Experimental/inducido químicamente,
Diabetes Mellitus Experimental/tratamiento farmacológico,
Modelos Animales de Enfermedad,
Fabaceae,
Hiperplasia/patología,
Hipoglucemiantes/farmacología,
Fitoterapia,
Extractos Vegetales/farmacología,
Hojas de la Planta,
Ratas Wistar,
Estreptozocina
OBJECTIVE: To test whether swimming training benefits femoral neck strength in young diabetic rats under insulin therapy. METHODS: A total of 60 male Wistar rats (age: 40 days) were divided equally into the following six groups: control sedentary, control exercise, diabetic sedentary, diabetic exercise,...
Glucemia/análisis,
Peso Corporal/fisiología,
Hueso Esponjoso/fisiopatología,
Colágeno/análisis,
Diabetes Mellitus Experimental/tratamiento farmacológico,
Diabetes Mellitus Experimental/fisiopatología,
Terapia por Ejercicio/métodos,
Cuello Femoral/fisiopatología,
Fracturas Óseas/fisiopatología,
Fracturas Óseas/prevención & control,
Hipoglucemiantes/uso terapéutico,
Insulina/uso terapéutico,
Condicionamiento Físico Animal/fisiología,
Ratas Wistar,
Reproducibilidad de los Resultados,
Estreptozocina,
Natación/fisiología,
Factores de Tiempo
Abstract Purpose: To investigate the effects of exenatide on renal injury in streptozotocin-induced diabetic rats. Methods: Fifty SD rats were randomly divided into normal control, model, exenatide-1, exenatide-2 and exenatide-3 groups, 10 rats in each group. The diabetic nephropathy model was constr...
This study was aimed to search the effect of wheatgrass on the Total Antioxidan (TAS)-Oxidan Status (TOS) and DNA damage in rat with diabetes. The rats used in the study were randomly divided into 4 groups that each of has 10 rats: Control group; 1 ml single dose phosphate-citrate buffer injected i.p (pH...
Triticum/química,
Extractos Vegetales/administración & dosificación,
Diabetes Mellitus Experimental/tratamiento farmacológico,
Antioxidantes/análisis,
Estrés Oxidativo/efectos de los fármacos,
Páncreas/efectos de los fármacos,
Ratas Wistar,
Daño del ADN/efectos de los fármacos,
Oxidantes/sangre,
Células Secretoras de Insulina/efectos de los fármacos,
Extractos Vegetales/farmacología,
Glucemia/efectos de los fármacos
Kidney injury secondary to diabetes is the most common cause of kidney failure. We sought to determine whether pretreatment with the insulin-sensitizing drug metformin prior to the induction of diabetes can protect the kidney against the development of diabetic nephropathy (DN) induced by a combination o...
Ulomoides dermestoides is a beetle traditionally consumed to treat diabetes. In this study, we performed a composition analysis of U. dermestoides to obtain the principal fractions, which were used to assess the effect on glycemia, liver and pancreatic architecture, and PPARγ and GLUT4 expression. N...
Escarabajos/química,
Diabetes Mellitus Experimental/tratamiento farmacológico,
Diabetes Mellitus Experimental/metabolismo,
Diabetes Mellitus Experimental/patología,
Cuerpo Adiposo/química,
Cromatografía de Gases y Espectrometría de Masas,
Regulación de la Expresión Génica,
Transportador de Glucosa de Tipo 4/efectos de los fármacos,
Transportador de Glucosa de Tipo 4/metabolismo,
Hipoglucemiantes/aislamiento & purificación,
Hipoglucemiantes/uso terapéutico,
Hígado/efectos de los fármacos,
Hígado/metabolismo,
Hígado/patología,
PPAR gamma/efectos de los fármacos,
PPAR gamma/metabolismo,
Páncreas/efectos de los fármacos,
Páncreas/metabolismo,
Páncreas/patología,
ARN Mensajero/efectos de los fármacos,
ARN Mensajero/metabolismo,
Extractos de Tejidos/aislamiento & purificación,
Extractos de Tejidos/uso terapéutico
BACKGROUND: Diabetic nephropathy (DN) is the leading cause of end-stage renal failure, contributing to severe morbidity and mortality in diabetic patients. Berberine (BBR) has been well characterized to exert renoprotective effects in DN progression. However, the action mechanism of BBR in DN remains to ...
SUMMARY: Diabetes mellitus is a common metabolic disease. There are many natural agents available to control and treat diabetes. Crab shell extract has antioxidant properties. The aim of present study was to investigate the effect of crab shell hydroalcoholic extract on blood glucose, liver enzymes, nitr...
Diabetes mellitus is a common serious metabolic illness occurring worldwide that may lead to male infertility. Various plants have been used in the treatment of diabetes. In this study, the effect of garden cress (Lepidium sativum) seed extract on fasting blood sugar is assessed for its protective effect...
Diabetes mellitus is a frequent and serious metabolic illness all over the world and plants have been a desirable source of medicine recently. Diabetes has unpleasant effect on male reproductive system and it may lead to male infertility. It causes erectile dysfunction and reduces ejaculate volume by aff...
