Os ácidos micólicos, principais componentes da parede celular do M. tuberculosis, são alvos específicos para o planejamento de novos agentes potenciais contra a tuberculose (TB) e o estudo de seu processo biossintético é de importância fundamental no desenvolvimento de inibidores mais seletivos. �...
The telomerase is a ribonucleoprotein enzyme to which multiple functions have been attributed, the most important of these is the maintenance of the telomere which is related with cellular immortalization and cancer. 85 of human tumors have telomerase activity, that in normal cells goes undetected. These...
Search of new activity substances starting from chemotherapeutic agents, continously appears in international literature. Perhaps this search has been done more frequently in the field of anti-tumor chemotherapy on account of the unsuccess in saving advanced stage patients. The new point in this matter d...
