Evaluar los efectos de la terapia hormonal (TH) con Drospírenona (DRSP)/17 β -estradiol (E2), sobre los parámetros
del Síndrome Metabólico (SM) en pacientes postmenopáusicas. Métodos: Investigación comparativa y aplicada, con diseño cuasi experimental, de casos y controles a simple ciego, prospe...
Un tercio de la población mundial tiene niveles anormalmente altos de presión arterial, hipertensión, responsable de casi el 50% de las muertes por accidente cerebrovascular y enfermedad coronaria. La sensibilidad a la sal es un factor de riesgo para la morbilidad y mortalidad cardiovascular y tambié...
Eosinophils are abundant in the reproductive tract, contributing to the remodeling and successful implantation of the embryo. However, the mechanisms by which eosinophils migrate into the uterus and their relationship to edema are still not entirely clear, since there are a variety of chemotactic factors...
Considering that female sexual hormones may modulate the inflammatory response and also exhibit direct effects on the cells of the immune system, herein, we intend to discuss the sex differences and the role of estradiol in modulating the lung and systemic inflammatory response, focusing on its possible ...
Betacoronavirus,
COVID-19,
Infecciones por Coronavirus/terapia,
Estradiol/uso terapéutico,
Inmunidad Innata,
Inflamación/tratamiento farmacológico,
Inflamación/virología,
Pandemias,
Neumonía Viral/terapia,
SARS-CoV-2,
Factores Sexuales
Abstract Menopause induces oral bone loss, leading to various oral diseases. Mastication importantly affects bone metabolism in the jawbone. Objective: To analyze the effect of enhanced masticatory force on osteoprotegerin (OPG), receptor activator of nuclear factor kappa B ligand (RANKL), and mechano-g...
Fosfatasa Alcalina/sangre,
Proceso Alveolar/fisiopatología,
Fuerza de la Mordida,
Western Blotting,
Ensayo de Immunospot Ligado a Enzimas,
Estradiol/sangre,
Factor I del Crecimiento Similar a la Insulina/análisis,
Osteocalcina/sangre,
Osteoprotegerina/análisis,
Ovariectomía,
Ligando RANK/análisis,
Ratas Sprague-Dawley,
Reacción en Cadena de la Polimerasa,
Microtomografía por Rayos X
ABSTRACT Objective: To present a case of bilateral gynecomastia in a prepubertal boy with autism spectrum disorder, diagnosed with myotonic dystrophy type 1. Case description: A 12-year-old boy with autism spectrum disorder presented at a follow-up visit with bilateral breast growth. There was a fami...
Trastorno del Espectro Autista,
Estradiol/química,
Genitales Masculinos/anatomía & histología,
Ginecomastia/sangre,
Ginecomastia/etiología,
Distrofia Miotónica/sangre,
Distrofia Miotónica/complicaciones,
Distrofia Miotónica/diagnóstico,
Distrofia Miotónica/genética,
Proteína Quinasa de Distrofia Miotónica/genética,
Linaje,
Pubertad,
Testosterona/sangre
Durante o climatério, período em que as gônadas femininas cessam sua função, a deficiência de estrógenos, especialmente do estradiol, provoca alterações importantes na cavidade bucal, interferindo em mecanismos inflamatórios, secreção salivar, metabolismo do colágeno, entre outros. Por meio ...
Abstract Objective To investigate the action of testosterone (T), isolated or associated with estradiol benzoate (EB), on the proliferation markers and apoptosis of breasts of ovariectomized rats. Methods A total of 48 castrated female Wistar rats were divided into 6 groups, and each of them were sub...
Apoptosis/efectos de los fármacos,
Biomarcadores/análisis,
Mama/citología,
Mama/patología,
Calcinosis/patología,
Caspasa 3/análisis,
Proliferación Celular/efectos de los fármacos,
Estradiol/análogos & derivados,
Estradiol/farmacología,
Ovariectomía,
Antígeno Nuclear de Célula en Proliferación/análisis,
Ratas Wistar,
Testosterona/farmacología
ABSTRACT: Tooth eruption requires resorption of the alveolar bone interposed between the tooth germ and the oral mucosa (coronal bone). The cells responsible for bone resorption are the osteoclasts and their activity can be reduced or inactivated by estrogen hormone. We aimed to investigate the effects o...
Erupción Dental/fisiología,
Proceso Alveolar/fisiología,
Remodelación Ósea/fisiología,
Osteoclastos,
Resorción Ósea/fisiopatología,
Ratas Wistar,
Estrógenos/administración & dosificación,
Estrógenos/efectos adversos,
Comités de Ética,
Inmunohistoquímica/métodos,
Estradiol/farmacología,
28599,
Estrógenos/uso terapéutico,
Receptores de Estrógenos,
Experimentación Animal
Abstract Cheirodon interruptus is a ubiquitous small characid that inhabits the Pampean region and commonly used as bait. Its vast market is supplied from the wild population causing a significant environmental impact. In this study, we assess the effect of photoperiod on ovarian maturation in order to e...
