Bauhinia
genus comprises 300 diferent species distributed in tropical and subtropical forests.
Infusions of some species have been frequently used in folk medicine to treat several ailments, especially
diabetes. S
tudies are focused on the extracts and little is reported about their esse...
Triterpenes are very important secondary metabolites with wide structural diversity and
significant role in pharmacy and medicine.
In the present research, a comparative study of
pharamacological activities of the triterpene fractions obtained from several pla...
SUMMARY: Cisplatin (Cis) is an important chemotherapeutic agent used in cancer treatment. Males exposed to Cis were reported to exhibit testicular toxicity. Cis-induced testicular toxicity is mediated by oxidative stress, inflammation, testosterone inhibition and apoptosis. Accordingly, this study was co...
Camellia sinensis/química,
Extractos Vegetales/farmacología,
Té/química,
Infliximab/farmacología,
Cisplatino/toxicidad,
Testículo/efectos de los fármacos,
Recuento de Espermatozoides,
Factor de Necrosis Tumoral alfa/antagonistas & inhibidores,
Apoptosis,
Estrés Oxidativo,
Inflamación,
Ratas Sprague-Dawley,
Extractos Vegetales/química,
Inmunohistoquímica,
Malondialdehído/análisis,
Glutatión/análisis,
Testículo/patología
The purpose of this work was to evaluate the antioxidant capacity of Prosopis pallida (Fabaceae) fruits “algarrobo”, in addition to determine their main chemical components. Fruit purified extracts from the regions of Tumbes, Piura, Lambayeque, and La Libertad (Peru) were eval...
Prosopis/química,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Antioxidantes/farmacología,
Perú,
Medicina Tradicional,
Plantas Medicinales,
Antioxidantes/química,
Polifenoles/análisis,
Flavonoides/análisis,
Cromatografía Líquida de Alta Presión,
Cromatografía Líquida con Espectrometría de Masas
dos Santos, Jymmys Lopes;
Silva, Ana Mara de Oliveira e;
Souza, Lúcio Marques Vieira;
Pereira, Raquel Oliveira;
Lima, Clésio Andrade;
Abreu, Lucas Silva;
Montalvao, Monalisa Martins;
Correa, Cristiane Bani;
Rabelo, Thallita Kelly;
Duarte, Marcelo Cavalcante;
Aidar, Felipe Jose;
Tavares, Josean Fechine;
Estevam, Charles dos Santos;
Marçal, Anderson Carlos.
In order to understand antidiabetic potential and toxicity, this study aimed to evaluate the acute toxicity and antidiabetic activity of ethanolic extract and ethyl acetate fraction obtained from Coutoubea spicata “nicolau” shoots. Chemical constituents and acute toxicity were investigated. In alloxa...
Extractos Vegetales/química,
Extractos Vegetales/toxicidad,
Extractos Vegetales/farmacología,
Etanol,
Diabetes Mellitus/tratamiento farmacológico,
Gentianaceae/química,
Hiperglucemia/tratamiento farmacológico,
Hipoglucemiantes/química,
Hipoglucemiantes/farmacología,
Cromatografía Líquida de Alta Presión,
Flavonoides/análisis,
Fenoles/análisis,
Supervivencia Celular,
Ratas Wistar,
Peso Corporal/efectos de los fármacos,
Oxidación-Reducción/efectos de los fármacos,
Hipoglucemiantes/toxicidad
Venegas-Casanova, Edmundo;
Gavidia-Valencia, José G;
Curo-Vallejos, Yuri F;
Ríos, Miguel;
Chavez-Abanto, Luis A;
Aro-Díaz, Ruben J;
Escobar, Jorge;
Rubio-López, Felipe Ruben;
Uribe-Villarreal, José;
Martinez, José L;
Rengifo-Penadillos, Roger A.
The conversion factor of nitrogen to proteins and isoflavones present in Glycine max was determined. For the determination of the conversion factor, we worked with solubilizing the proteins at alkaline pH and then extracting them with acidic pH. The proteins were iden...
Phytochemical bio-guided studies are used to find compounds with biological activity. Flavonoids from seeds of Leucaena species have antimicrobial activity in strains of medical interest, therefore, fresh seeds were collected from the town of Tlayacapan, Morelos, Mexico. ...
Fabaceae/química,
Extractos Vegetales/química,
Antiinfecciosos/química,
Inositol/aislamiento & purificación,
Inositol/análogos & derivados,
Cromatografía Líquida de Alta Presión,
Escherichia coli/efectos de los fármacos,
Semillas/química,
Flavonoides/aislamiento & purificación,
Pruebas de Sensibilidad Microbiana,
Extractos Vegetales/farmacología,
México
Annona muricata Linn. (Annonaceae) is a tropical plant with multiple beneficial health effects including anticancer properties. In breast cancer patients, overexpression of the HER2 oncoprotein corresponds to a poor prognosis, thus the main purpose of this study was to evaluate the cytotoxici...
Annona/química,
Plantas Medicinales,
Antineoplásicos Fitogénicos/uso terapéutico,
Neoplasias de la Mama/tratamiento farmacológico,
Antineoplásicos Fitogénicos/farmacología,
Células MCF-7/efectos de los fármacos,
Leucocitos Mononucleares,
Proliferación Celular/efectos de los fármacos,
Extractos Vegetales/uso terapéutico,
Extractos Vegetales/farmacología,
Antineoplásicos Fitogénicos/química,
Extractos Vegetales/química,
Fenoles/análisis,
Concentración 50 Inhibidora
Objetivo: Obtener un fitofármaco a base de extracto seco de limón con estándares de calidad, procesamiento amigable con el medio ambiente y con antecedentes de efectividad y seguridad, evaluando sus efectos en pacientes hipertensos con frecuentes crisis hipertensivas. Métodos y resultados: Se selecci...
Citrus/química,
Crisis Hipertensiva/tratamiento farmacológico,
Flavonoides/análisis,
Medicamento Fitoterápico,
Jugos de Frutas y Vegetales,
Ácido Ascórbico/análisis,
Espectrofotometría,
Cromatografía Líquida de Alta Presión,
Extractos Vegetales/uso terapéutico,
Extractos Vegetales/farmacología,
Presión Arterial/efectos de los fármacos,
Factores de Tiempo,
d0056120,
d0112080
The neuroprotective effect of flower and fruit parts of Capparis ovata Desf. var. palaestina Zoh. plant was investigated in H2O2-induced cytotoxicity in SH-SY5Y cells. The cells were treated with H2O2 alone or pretreated with flower (COMFL) and fruit extract (COMFR) of C. ovatavar. palaesti...
Capparis/química,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Fármacos Neuroprotectores/farmacología,
Fármacos Neuroprotectores/química,
Peróxido de Hidrógeno/toxicidad,
Cromatografía Líquida con Espectrometría de Masas,
Espectrometría de Masas en Tándem,
Neuroblastoma,
Estrés Oxidativo/efectos de los fármacos,
Muerte Celular/efectos de los fármacos,
Ácidos Cafeicos/análisis,
Flavonoides/análisis,
Fenoles/análisis,
Ácidos Grasos Monoinsaturados/análisis,
Enfermedades Neurodegenerativas/prevención & control
