Results: 30

Infliximab in patients with psoriasis and other inflammatory diseases: evaluation of adverse events in the treatment of 168 patients

An. bras. dermatol; 91 (3), 2016
Abstract: Background: Psoriasis is immune-mediated chronic inflammatory disease with preference for skin and joints. The skin involvement occurs by hyperproliferation and abnormal differentiation of keratinocytes. It is associated with comorbidities, mainly related to the clinical manifestations of the ...

Effects of platelet rich plasma on fascial healing in rats with fecal peritonitis

Acta cir. bras; 31 (5), 2016
ABSTRACT PURPOSE : To evaluate the effects of platelet rich plasma (PRP) on the healing of fascia wherein peritonitis has been created. METHODS: Twenty eight Wistar Albino rats were divided into four groups. Only a primary fascial repair following laparotomy was performed on Group 1, a primary fascial...

Avaliação do papel do sistema canabidiol em um modelo de lesão renal por isquemia/reperfusão em animais

RESUMO Objetivo: Investigar os efeitos da administração de canabidiol em um modelo de isquemia/reperfusão renal em animais. Métodos: Foi induzida uma lesão renal, por meio de 45 minutos de isquemia renal seguida por reperfusão. Administrou-se canabidiol (5mg/kg) imediatamente após a reperfusão. R...

Ethanol during adolescence decreased the BDNF levels in the hippocampus in adult male Wistar rats, but did not alter aggressive and anxiety-like behaviors

Objective:To investigate the effects of ethanol exposure in adolescent rats during adulthood by assesssing aggression and anxiety-like behaviors and measuring the levels of inflammatory markers.Methods:Groups of male Wistar rats (mean weight 81.4 g, n = 36) were housed in groups of four until postnatal d...

Effects of Er-Miao-San extracts on TNF-alpha-indueed MMP-1 expression in human dermal fibroblasts

Biol. Res; 48 (), 2015
BACKGROUND: Various health benefits have been attributed to Er-Miao-San (EMS), a traditional Chinese herbal formulation that contains equal amounts of cortex phellodendri (Phellodendron amurense Ruprecht) and rhizoma atractylodis (Atractylodes lancea D.C). However, its effect on the anti-inflammatory act...

Lipoaspiração: atualização dos fatores de riscos metabólicos e sua importância clínico-cirúrgica

Rev. bras. cir. plást; 29 (3), 2014
A lipoaspiração permanece como um dos procedimentos mais realizados pelos cirurgiões plásticos (1-3). O aumento da segurança no ambiente cirúrgico, o refinamento da técnica e a satisfação das pacientes contribuem para a popularidade desta intervenção idealizada por Ilouz, em 1979 (4). Tem-se o...

Diabetic retinopathy: could the alpha-1 antitrypsin be a therapeutic option?

Biol. Res; 47 (), 2014
Diabetic retinopathy is one of the most important causes of blindness. The underlying mechanisms of this disease include inflammatory changes and remodeling processes of the extracellular-matrix (ECM) leading to pericyte and vascular endothelial cell damage that affects the retinal circulation. In turn, ...

Apoptosis in HEp-2 cells infected with Ureaplasma diversum

Biol. Res; 47 (), 2014
BACKGROUND: Bacterial pathogens have many strategies for infecting and persisting in host cells. Adhesion, invasion and intracellular life are important features in the biology of mollicutes. The intracellular location ofUreaplasma diversum may trigger disturbances in the host cell. This includes activat...

Normalization of the levels of inflammatory molecules in Mycobacterium smegmatis-infected U937 cells by fibrate pretreatment

Biol. Res; 47 (), 2014
BACKGROUND: Tuberculosis (TB) is a respiratory tract disease caused by Mycobacterium tuberculosis infection. M. tuberculosis exploits immune privilege to grow and divide in pleural macrophages. Fibrates are associated with the immune response and control lipid metabolism through glycolysis with β-oxidat...

Correlación entre factor de crecimiento insulínico tipo 1 (IGF-1), citoquinas proinflamatorias y activación neurohumoral en pacientes con isuficiencia cardíaca crónica avanzada
Correlation of insulin like growth factor (IGF-1), cytokines and neurohumoral activation in patiens with advanced congestive heart failure

Rev. chil. cardiol; 17 (2), 1998
Hemos demostrado previamente que la actividad del eje hormona de crecimiento (GH) y su mediador activo, el factor de crecimiento insulínico tipo 1 (IGF-1) se encuentra disminuido en pacientes (pts) con insuficiencia cardíaca crónica (ICC). Por otra parte, se ha reportado que otras moléculas biológic...