Results: 200

Methylophiopogonanone A, an Ophiopogon homoisoflavonoid, alleviates high-fat diet-induced hyperlipidemia: assessment of its potential mechanism

Braz. j. med. biol. res; 53 (3), 2020
Methylophiopogonanone A (MO-A), a homoisoflavonoid extracted from Ophiopogon japonicus, has been shown to attenuate myocardial apoptosis and improve cerebral ischemia/reperfusion injury. However, the hypolipidemic effects remain unknown. This study was performed to investigate a potential hypolipidemic e...

Exploring the shared genes of hypertension, diabetes and hyperlipidemia based on microarray

Given their relationship with metabolic syndrome and systematic inflammatory diseases, the pathogenesis of hypertension, hyperglycemia, and hyperlipidemia is closely related. To explore the common genes among these three conditions, spontaneous hypertensive rats (SHR), spontaneous diabetic Goto-Kakizaki ...

Xantoma del tendón de aquiles bilateral: debut de xantomatosis cerebrotendinosa

OBJETIVO Presentación de un inusual caso de xantomatosis cerebrotendinosa en un paciente de edad cuya primera manifestación fueron xantomas bilaterales del tendón de Aquiles. MATERIAL Y MÉTODOS Mujer de 62 años, que presenta tumoraciones, que presenta tumoraciones sólidas y polilobuladas, en la...

Perfil lipídico mínimo para el diagnóstico del riesgo de enfermedad vascular periférica de los miembros inferiores
Minimum lipid profile for the diagnostic of the peripheral vascular disease's risk

Introducción: El perfil lipídico mínimo está relacionado con la enfermedad vascular de tipo aterosclerótica, pero se desconoce cuál es el tipo de perfil más frecuente en los adultos y el tipo de riesgo que representan para la enfermedad vascular periférica de los miembros inferiores. Objetivo: ...

Comparación de puntajes de riesgo para predecir aterosclerosis subclínica
Comparison of risk scores to predict subclinical atherosclerosis

Medicina (B.Aires); 79 (5), 2019
La aterosclerosis subclínica es un potente predictor de eventos cardiovasculares, aunque se desconoce cuál de los puntajes de riesgo es más eficaz para predecir su presencia en una población latinoamericana. El objetivo fué comparar la performance de los puntajes de riesgo: Framingham, Regicor y Ath...

Effect of Hydro-alcoholic Extract from Prosopis Farcta Leaves on Liver Injury Caused by High-fat Diet in Rats

West Indian med. j; 68 (1), 2019
ABSTRACT Objective: To determine the hepatoprotective and antioxidant effects of hydro-alcoholic extract of Prosopis farcta (P farcta) leaves on high fat diet-fed (HFDF) rats. Methods: In this experimental study, 40 male Wistar rats were divided into four groups - group 1: normal control group; group 2...

Vitamin D deficiency is not associated with higher levels of syntax score

Abstract Objective: To evaluate the association between serum vitamin D (vitD) level and SYNTAX (synergy between percutaneous coronary intervention with taxus and cardiac surgery) score (SS). Methods: The medical records of consecutive patients, who underwent coronary artery bypass graft surgery, were ...

Nuevas guías europeas sobre el control de la dislipidemia afrontan el reto C-LDL
New European guidelines on dyslipidemia control face the LDL-C challenge

Med. interna (Caracas); 35 (3), 2019

Association of Severity of Coronary Lesions with Bone Mineral Density in Postmenopausal Women

Arq. bras. cardiol; 110 (3), 2018
Abstract Background: Coronary artery disease (CAD) and osteoporosis (OP) are common diseases in postmenopausal women. In both cross-sectional and longitudinal epidemiologic studies, low bone mass has been related to increased frequency of CAD. However, available data on the relationship between bone min...

Large Accumulation of Collagen and Increased Activation of Mast Cells in Hearts of Mice with Hyperlipidemia

Arq. bras. cardiol; 109 (5), 2017
Abstract Background: Hyperlipidemia, which is characterized by an elevation of lipids in the bloodstream, is a major risk factor for cardiac disease. Objectives: The present study investigated the role of fibrosis in the progression of hyperlipidemia in the mice heart, and whether mast cell activation ...