Results: 46

Informe diário de evidências COVID-19: busca realizada em 30 de junho de 2020
COVID-19 daily evidence report: search conducted on June 30, 2020

O Informe Diário de Evidências é uma produção do Ministério da Saúde que tem como objetivo acompanhar diariamente as publicações científicas sobre tratamento farmacológico e vacinas para a COVID-19. Dessa forma, são realizadas buscas estruturadas em bases de dados biomédicas, referente ao di...

Association between statin use and mortality risks during the acute phase of ischemic stroke in patients admitted to an intensive care unit

Arq. neuropsiquiatr; 78 (3), 2020
Abstract Ischemic stroke is a common cause of death. The role of statins in the secondary prevention of the chronic ischemic stroke phase has been established. However, evidence regarding their efficacy in this phase is limited and contradictory. Objective: To evaluate the association between statin us...

Aspirin with or without statin in the treatment of endotheliitis, thrombosis, and ischemia in coronavirus disease

Abstract INTRODUCTION: In the genesis of coronavirus disease (COVID-19), there is a process of endotheliitis associated with thrombotic changes, no studies have reported the use of acetylsalicylic acid (ASA) as a possible therapeutic approach. Statins could potentiate the ASA therapy. METHODS: This i...

New 2018 ACC/AHA Guidelines on Cholesterol Management: Key Changes and Implications

Should all patients with psoriasis receive statins? Analysis according to different strategies

An. bras. dermatol; 94 (6), 2019
Abstract Background: Different strategies have been proposed for the cardiovascular risk management of patients with psoriasis. Objective: To estimate the cardiovascular risk and evaluate two cardiovascular prevention strategies in patients with psoriasis, analyzing which proportion of patients would b...

Elegibilidad para la indicación de inhibidores de PCSK9 según las recomendaciones de diferentes sociedades científicas
Eligibility for the indication of PCSK9 inhibitors according to the recommendations of different scientific societies

Medicina (B.Aires); 79 (2), 2019
La reducción del colesterol-LDL (C-LDL) es un objetivo primordial en prevención cardiovascular. Estudios recientes demostraron beneficio clínico al administrar inhibidores de la proprotein convertase subtilisin/kexin-9 (iPCSK9) a pacientes que no habían logrado la meta de C-LDL con estatinas de alta ...

An atypical presentation of a severe and massive atheroembolic disease

J. bras. nefrol; 41 (1), 2019
ABSTRACT Atheroembolic renal disease (AERD) is a kidney manifestation of atherosclerosis as a systemic disease. AERD is defined as a renal impairment secondary to embolization of cholesterol crystals with consequent occlusion of renal vascularization. The current case report describes one patient with mu...

Lipid profile and statin use in critical care setting: implications for kidney outcome

Einstein (Säo Paulo); 17 (3), 2019
ABSTRACT Objective: To determine whether pre-hospital statin use is associated with lower renal replacement therapy requirement and/or death during intensive care unit stay. Methods: Prospective cohort analysis. We analyzed 670 patients consecutively admitted to the intensive care unit of an academic t...

Estatinas, drogas de amplio espectro de acción y beneficios
Statins, drugs with a wide spectrum of action and benefits

Prevention and treatment of dyslipidemia should therefore be considered as an integral part of individual cardiovascular prevention interventions, which should be addressed primarily to those at higher risk who will benefit most. Statins are the most commonly used options for the pharmacologic treatment ...