SUMMARY: The geese's tongue filiform papillae are particularly long, and exhibit the same morphology of a tooth, evoking the lingual teeth of several fishes. In adult animals, they contain numerous mechanical Herbst's corpuscles but no taste buds. In the embryo, they appear since stage 38 and acquire the...
SUMMARY: Colon adenocarcinoma (COAD) is a prevalent disease worldwide, known for its high mortality and morbidity rates. Despite this, the extent of investigation concerning the correlation between COAD's CLCA1 expression and immune cell infiltration remains insufficient. This study seeks to examine the ...
Canales de Cloruro/metabolismo,
Neoplasias del Colon/inmunología,
Adenocarcinoma/inmunología,
Biología Computacional,
Pronóstico,
Análisis de Supervivencia,
Análisis de Regresión,
Análisis Multivariante,
Inmunohistoquímica,
Canales de Cloruro/inmunología,
Neoplasias del Colon/metabolismo,
Adenocarcinoma/metabolismo
SUMMARY: The aim of this study is to reveal the gonadoprotective effects of myricetin (MYC), which has many biological properties, on cisplatin (CP)-induced testicular damage in rats. For this purpose, 40 male Wistar albino rats were divided into 4 groups as Control (group given no treatment), MYC (group...
Flavonoides/administración & dosificación,
Flavonoides/farmacología,
Testículo/lesiones,
Testículo/efectos de los fármacos,
Cisplatino/toxicidad,
Antineoplásicos/toxicidad,
Respuesta al Choque Térmico,
Inflamación,
Ratas Wistar,
Receptor Toll-Like 4,
FN-kappa B,
Inmunohistoquímica,
Etiquetado Corte-Fin in Situ
SUMMARY: The therapeutic effect of a granulocyte-colony stimulating factor (G-CSF) biosimilar drug, zarzio, on non-alcoholic fatty liver disease (NAFLD) in a rat model was investigated in this study. Thirty-two rats were randomly divided into four groups. Groups I and II were fed a standard laboratory di...
Factor Estimulante de Colonias de Granulocitos/administración & dosificación,
Biosimilares Farmacéuticos/administración & dosificación,
Enfermedad del Hígado Graso no Alcohólico/tratamiento farmacológico,
Modelos Animales de Enfermedad,
Inmunohistoquímica,
Factor de Necrosis Tumoral alfa/efectos de los fármacos,
Células Secretoras de Insulina/efectos de los fármacos,
Factor 2 Relacionado con NF-E2,
d0009750,
Dieta Alta en Grasa/efectos adversos,
Caspasa 3
INTRODUCCIÓN. El gen Tp53 proporciona instrucciones para producir proteína tumoral 53. El Tp53 es un gen supresor tumoral que protege el ciclo celular, reparando el ADN o activando la apoptosis. Es clave en la carcinogénesis del carcinoma basocelular, patología que cobra relevancia en Ecuador, debido...
Elkattawy, Hany A;
El-Sayed-Hassan, Ahmed;
Ebrahim-Alsemeh, Amira;
Abdelwahab, Ola A;
Eldesoqui, Mamdouh;
El-Sherbiny, Mohamed;
Ebrahim, Hasnaa Ali;
Nosseir, Nermine Samir;
Veeraraghavan, Vishnu Priya;
Ghazala, Mohamed;
Attia, Mohammed A;
Hadhoud, Shimaa.
SUMMARY: The main cause of mortality and disability globally is myocardial infarction (MI). Isoproterenol (ISO), a β-adrenoceptor agonist, has been used to induce rat myocardial necrosis. Whereas interleukin-37 (IL-37) has anti-inflammatory and cytoprotective properties. The study aimed to investiga...
SUMMARY: Cisplatin (Cis) is an important chemotherapeutic agent used in cancer treatment. Males exposed to Cis were reported to exhibit testicular toxicity. Cis-induced testicular toxicity is mediated by oxidative stress, inflammation, testosterone inhibition and apoptosis. Accordingly, this study was co...
Camellia sinensis/química,
Extractos Vegetales/farmacología,
Té/química,
Infliximab/farmacología,
Cisplatino/toxicidad,
Testículo/efectos de los fármacos,
Recuento de Espermatozoides,
Factor de Necrosis Tumoral alfa/antagonistas & inhibidores,
Apoptosis,
Estrés Oxidativo,
Inflamación,
Ratas Sprague-Dawley,
Extractos Vegetales/química,
Inmunohistoquímica,
Malondialdehído/análisis,
Glutatión/análisis,
Testículo/patología
SUMMARY: Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is highly expressed in various types of cancers including breast cancer. However, the role of AhR with its endogenous ligand 2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE) on the progression...
Indoles/administración & dosificación,
Tiazoles/administración & dosificación,
Receptores de Hidrocarburo de Aril/efectos de los fármacos,
Neoplasias de la Mama/patología,
Indoles/farmacología,
Tiazoles/farmacología,
Receptores de Estrógenos,
Inmunohistoquímica,
Proliferación Celular/efectos de los fármacos,
Citometría de Flujo,
Ensayos de Migración Celular,
Western Blotting,
Línea Celular Tumoral/efectos de los fármacos,
Citocromo P-450 CYP1A1/genética,
Citocromo P-450 CYP1B1/genética
SUMMARY: In solid and malignant tumors, innate and adaptive immunity are combined in antitumor responses. This study aimed to analyze the activation of plasma cells and the correlation between the infiltration of B and T lymphocytes with the degree of malignancy or Gleason grade in human prostate biopsie...
Objective: The present study aims to evaluate the viability of adult human neural cells in culture obtained from traumatized brain tissues collected in emergency surgery procedures. Methods: Exploratory, descriptive, quantitative and cross-sectional study evaluating samples obtained from patients who und...
Inmunohistoquímica,
d0034300,
Técnicas de Cultivo de Célula,
Neuronas,
Heridas y Lesiones,
Lesiones Encefálicas,
Traumatología,
d0024770,
d0019210,
d0000706420,
d0094170
