CONTEXTO: Os PCDT são documentos que visam garantir o melhor cuidado de saúde diante do contexto brasileiro e dos recursos disponíveis no SUS. Podem ser utilizados como materiais educativos aos profissionais de saúde, auxílio administrativo aos gestores, regulamentação da conduta assistencial pera...
Miastenia Gravis/diagnóstico,
Acetilcolina/sangre,
Protocolos Clínicos/normas,
Estimulación Eléctrica/métodos,
Diagnóstico Diferencial,
Miastenia Gravis/tratamiento farmacológico,
Inhibidores de la Colinesterasa/uso terapéutico,
Inmunosupresores/uso terapéutico,
Inmunoglobulinas/uso terapéutico,
Plasmaféresis/instrumentación,
Timectomía/instrumentación,
Sistema Único de Salud,
Brasil
This study aimed to identify, by means of thromboelastometry assessment, altered thrombotic risk in dogs with primary and secondary IMHA by E. canis infection after initiating the immunosuppressive therapy with mycophenolate mofetil. The animals’ screening was based on complete blood count (CBC), bioch...
ABSTRACT A 45-year-old female patient presented with a complaint of right eye redness and pain for 7 days. She was under investigation for urinary abnormalities and reported a previous history of recurrent oral ulcers and ocular hyperemia in both eyes. Best-corrected visual acuity was 20/30 and 20/20 in ...
Tacrolimus (TAC), a calcineurin inhibitor, and everolimus (EVL), an mTOR inhibitor, have been used as immunosuppressive (ISS) drugs in post-kidney transplantation therapy. The objective of this study was to compare the efficacy of EVL vs TAC in the ISS maintenance triple therapy. Ninety-seven kidney tran...
ABSTRACT OBJECTIVE To estimate the prevalence and variability of nonadherence to immunosuppressives and nonpharmacological treatment across kidney transplantation centers and two health access-disparate regions in Brazil. METHODS In a cross-sectional design, a random multistage sample of 1,105 patien...
ABSTRACT BACKGROUND: Autoimmune hepatitis (AIH) is a chronic liver disease, characterized by necroinflammation and autoimmune etiology. Studies evaluating the characteristics of patients with AIH are scarce in Brazil. OBJECTIVE: Our objective was to evaluate the profile of patients with AIH in a spec...
Instituciones de Atención Ambulatoria,
Azatioprina/uso terapéutico,
Brasil/epidemiología,
Estudios de Cohortes,
Hepatitis Autoinmune/diagnóstico,
Hepatitis Autoinmune/tratamiento farmacológico,
Hepatitis Autoinmune/epidemiología,
Inmunosupresores/uso terapéutico,
Ictericia/epidemiología,
Hígado/patología,
Cirrosis Hepática/epidemiología,
Persona de Mediana Edad,
Prednisona/uso terapéutico,
Estudios Retrospectivos
Abstract This is a narrative review of azathioprine. This medication is immunomodulatory and immunosuppressive, and it has been used widely through different medical specialties to modify disease. It has been proven useful for several dermatoses and it has encountered success when used as an off-label in...
Al igual que en las enfermedades autoinmunes y reumáticas, las infecciones por virus pueden ser disparadores de mecanismos inmunopatogénicos. El SARSCoV-2 puede causar la liberación de citocinas y provocar un daño tisular grave, sobre todo pulmonar, con peligro para la vida. Se suma a ello el riesgo ...
La alopecia areata es un tipo común de alopecia no cicatricial. Aunque la patogénesis exacta permanece sin dilucidar, se piensa que la alopecia areata tiene una etiología multifactorial en donde se interrelacionan predisposición genética y factores ambientales. En pacientes susceptibles, se han docu...