Objetivos. Proponer compuestos fenólicos presentes en el extracto metanólico de hojas de Clinopodium pulchellum (Kunth) Govaerts «panisara». Materiales y métodos. Se preparó un extracto metanólico de las hojas de Clinopodium pulchellum (Kunth) Govaerts «panisara», se determinó la solubilidad po...
Abstract This study aimed to carry out an ethnobotanical survey of medicinal plants used by inhabitants of the Rodeadouro Island, Jatoba Island and Massangano Island, located in The Submedium São Francisco River Valley. Also phytochemicals and preliminary pharmacological tests were performed to species...
Abstract Metallic nanoparticles have great potential as a chemotherapeutic agent. The aim of this study was to develop and characterize silver and gold nanoparticles using a simple method, as well as evaluating the potential cytotoxic activity in relation to the K-562 cell line. For the synthesis, a solu...
The composition of the essential oil obtained by hydrodistillation from Minthostachys mollis Griseb (Lamiaceae) aerial parts was determined by GC and GC/MS. Menthone (13.2%), pulegone (12.4%), cis-dihydrocarvone (9.8%) and carvacrol acetate (8.8%) were the main essential oil components. The cytotoxic act...
Lamiaceae,
Aceites Volátiles/farmacología,
Aceites Volátiles/química,
Cromatografía de Gases y Espectrometría de Masas,
Antioxidantes/farmacología,
Antioxidantes/química,
Supervivencia Celular/efectos de los fármacos,
Depuradores de Radicales Libres,
Compuestos de Bifenilo,
Picratos,
Perú,
Terpenos/análisis,
Bioensayo,
Calorimetría,
Línea Celular Tumoral/efectos de los fármacos
Abstract INTRODUCTION: In the present study, we determined the chemical composition of Clinopodium macrostemum essential oil obtained by microwave-assisted hydrodistillation and its effect on the growth and development of Culex quinquefasciatus mosquito larvae. METHODS: The essential oil compounds wer...
Bioensayo,
Culex/clasificación,
Culex/efectos de los fármacos,
Cromatografía de Gases y Espectrometría de Masas,
Lamiaceae/química,
Lamiaceae/clasificación,
Larva/efectos de los fármacos,
Dosificación Letal Mediana,
Microondas,
Aceites Volátiles/química,
Aceites Volátiles/aislamiento & purificación,
Aceites Volátiles/farmacología
Justus, Barbara;
Almeida, Valter Paes de;
Gonçalves, Melissa Marques;
Assunção, Daniele Priscila da Silva Fardin de;
Borsato, Debora Maria;
Arana, Andres Fernando Montenegro;
Maia, Beatriz Helena Lameiro Noronha Sales;
Paula, Josiane de Fátima Padilha de;
Budel, Jane Manfron;
Farago, Paulo Vitor.
ABSTRACT Lavandula dentata, popularly known as lavender, is commonly used in traditional medicine for the treatment of digestive and inflammatory disorders. The objective of this study was to analyzed the chemical oil composition, antioxidant and antimicrobial activities of the essential oil and anatomic...
GONÇALVES, REGIANE;
AYRES, VANESSA F S;
CARVALHO, CARLOS E;
SOUZA, MARIA G M;
GUIMARÃES, ANDERSON C;
CORRÊA, GEONE M;
MARTINS, CARLOS H G;
TAKEARA, RENATA;
SILVA, ELIANE O;
CROTTI, ANTÔNIO E M.
ABSTRACT Abnormal multiplication of oral bacteria causes dental caries and dental plaque. These diseases continue to be major public health concerns worldwide, mainly in developing countries. In this study, the chemical composition and antimicrobial activity of the essential oil of Vitex agnus-castus lea...
Antibacterianos/aislamiento & purificación,
Antibacterianos/farmacología,
Brasil,
Caries Dental/tratamiento farmacológico,
Cromatografía de Gases y Espectrometría de Masas,
Lacticaseibacillus casei/efectos de los fármacos,
Lamiaceae/química,
Aceites Volátiles/aislamiento & purificación,
Aceites Volátiles/farmacología,
Extractos Vegetales/farmacología,
Plantas Medicinales,
Sesquiterpenos Policíclicos,
Sesquiterpenos/clasificación,
Sesquiterpenos/farmacología,
Streptococcus mutans,
Vitex/química
Clinopodium gilliesii (Benth.) Kuntze, harvested in the Chilean highlands, contains a surprising 93.87% of the toxic monoterpene pulegone in the essential oil. These results show remarkable differences with studies of the same species carried out in Argentina and Peru. These dissimilarities in the monote...
ABSTRACT Natural steroids and triterpenes such as b-sitosterol, stigmasterol, lupeol, ursolic and betulinic acids were transformed into its hexanoic and oleic esters, to evaluate the influence of chemical modification towards the cytotoxic activities against tumor cells. The derivatives were evaluated ag...
Antineoplásicos/química,
Antineoplásicos/aislamiento & purificación,
Antineoplásicos/farmacología,
Línea Celular Tumoral,
Ensayos de Selección de Medicamentos Antitumorales,
Ésteres,
Fabaceae/química,
Fabaceae/clasificación,
Concentración 50 Inhibidora,
Lamiaceae/química,
Lamiaceae/clasificación,
Triterpenos Pentacíclicos/química,
Triterpenos Pentacíclicos/aislamiento & purificación,
Triterpenos Pentacíclicos/farmacología,
Triterpenos/química,
Triterpenos/aislamiento & purificación,
Triterpenos/farmacología
Rosmarinus officinalis L. (rosemary) and Origanum vulgare L. (oregano) are known to have antimicrobial properties, but studies on sporotrichosis are scarce. This study aimed to evaluate the anti-Sporothrix spp. activity of essential oils from commercial products and oils extracted from aerial parts of th...
