Tourinho-Barbosa, Rafael;
Srougi, Victor;
Nunes-Silva, Igor;
Baghdadi, Mohammed;
Rembeyo, Gregory;
Eiffel, Sophie S;
Barret, Eric;
Rozet, Francois;
Galiano, Marc;
Cathelineau, Xavier;
Sanchez-Salas, Rafael.
ABSTRACT Background Radical prostatectomy (RP) has been used as the main primary treatment for prostate cancer (PCa) for many years with excellent oncologic results. However, approximately 20-40% of those patients has failed to RP and presented biochemical recurrence (BCR). Prostatic specific antigen (P...
Adenocarcinoma/sangre,
Adenocarcinoma/diagnóstico,
Adenocarcinoma/economía,
Antígenos de Neoplasias/sangre,
Biomarcadores de Tumor/sangre,
Región del Caribe,
Análisis Costo-Beneficio,
Países en Desarrollo/economía,
Detección Precoz del Cáncer/economía,
América Latina,
Proteínas de Neoplasias/sangre,
Neoplasias de la Próstata/sangre,
Neoplasias de la Próstata/diagnóstico,
Neoplasias de la Próstata/economía,
Sensibilidad y Especificidad
Prostate cancer imaging has become an important diagnostic modality for tumor evaluation. Prostate-specific membrane antigen (PSMA) positron emission tomography (PET) has been extensively studied, and the results are robust and promising. The advent of the PET/magnetic resonance imaging (MRI) has added m...
O carcinoma epidermóide do pênis (CEP) representa 95% dos tipos de câncer de pênis. No Brasil, a incidência é de 2,7%, mas em algumas áreas do país, a incidência pode chegar a 17% dos casos diagnosticados de câncer por ano. É uma doença agressiva cuja sobrevida em 5 anos pode variar entre 85%...
ABSTRACT Purpose To find any influence on prognostic factors of index tumor according to predominant location. Materials and Methods Prostate surgical specimens from 499 patients submitted to radical retropubic prostatectomy were step-sectioned. Each transverse section was subdivided into 2 anterolat...
Estudios de Seguimiento,
Estimación de Kaplan-Meier,
Persona de Mediana Edad,
Clasificación del Tumor,
Estadificación de Neoplasias,
Pronóstico,
Antígeno Prostático Específico/sangre,
Prostatectomía,
Neoplasias de la Próstata/sangre,
Neoplasias de la Próstata/mortalidad,
Neoplasias de la Próstata/patología,
Neoplasias de la Próstata/cirugía,
Estudios Retrospectivos
Albuquerque, George A. M. Lins de;
Guglielmetti, Giuliano B;
Barbosa, João Arthur B. A;
Pontes J, José;
Fazoli, Arnaldo J. C;
Cordeiro, Maurício D;
Coelho, Rafael F;
Carvalho, Paulo Afonso de;
Gallucci, Fábio P;
Padovani, Guilherme P;
Park, Rubens;
Cury, José;
Nonemacher, Henrique;
Srougi, Miguel;
Nahas, William C.
Summary Objective: To evaluate the relation between serum total testosterone (TT) and prostate cancer (PCa) grade and the effect of race and demographic characteristics on such association. Method: We analyzed 695 patients undergoing radical prostatectomy (RP), of whom 423 had serum TT collected. Patie...
Hipogonadismo/sangre,
Hipogonadismo/complicaciones,
Hipogonadismo/etnología,
Clasificación del Tumor,
Pronóstico,
Antígeno Prostático Específico/sangre,
Neoplasias de la Próstata/sangre,
Neoplasias de la Próstata/complicaciones,
Neoplasias de la Próstata/etnología,
Neoplasias de la Próstata/patología,
Estudios Retrospectivos,
Factores de Riesgo,
Testosterona/sangre,
Testosterona/deficiencia
Summary Screening of prostate cancer with prostate-specific antigen (PSA) is a highly controversial issue. One part of the controversy is due to the confusion between population screening and early diagnosis, another derives from problems related to the quality of existing screening studies, the results ...
ABSTRACT Background Prostate-specific antigen densities have limited success in diagnosing prostate cancer. We emphasise the importance of the peripheral zone when considered with its cellular constituents, the “prostatocrit”. Objective Using zonal volumes and asymmetry of glandular acini...
Células Acinares/patología,
Biopsia,
Modelos Logísticos,
Persona de Mediana Edad,
Clasificación del Tumor,
Valor Predictivo de las Pruebas,
Próstata/patología,
Antígeno Prostático Específico/sangre,
Neoplasias de la Próstata/sangre,
Neoplasias de la Próstata/patología,
Curva ROC,
Estándares de Referencia,
Reproducibilidad de los Resultados,
Células del Estroma
ABSTRACT Introduction To assess predictive value of new tumor markers, precursor of prostate specific antigen (p2PSA) and its derivates-%p2PSA and prostate health index (PHI) in detection of patients with indolent and aggressive prostate cancer (PC) in a subcohort of man whose total PSA ranged from 2 t...
Biopsia,
Estudios Transversales,
Modelos Logísticos,
Persona de Mediana Edad,
Clasificación del Tumor,
Valor Predictivo de las Pruebas,
Próstata/patología,
Antígeno Prostático Específico/sangre,
Neoplasias de la Próstata/sangre,
Neoplasias de la Próstata/patología,
Precursores de Proteínas/sangre,
Curva ROC,
Valores de Referencia,
Reproducibilidad de los Resultados,
Estadísticas no Paramétricas
Abstract Introduction: Data from animal, clinical and prevention studies support the role of androgens in prostate cancer growth, proliferation and progression. Results of serum based epidemiologic studies in humans, however, have been inconclusive. The present study aims to define whether serum testost...
Biomarcadores de Tumor/sangre,
Biopsia/métodos,
Persona de Mediana Edad,
Valor Predictivo de las Pruebas,
Próstata/patología,
Antígeno Prostático Específico/sangre,
Neoplasia Intraepitelial Prostática/sangre,
Neoplasia Intraepitelial Prostática/patología,
Neoplasias de la Próstata/sangre,
Neoplasias de la Próstata/patología,
Estándares de Referencia,
Valores de Referencia,
Factores de Riesgo,
Testosterona/sangre
