Campos, Raquel Munhoz da Silveira;
Masquio, Deborah Cristina Landi;
Corgosinho, Flávia Campos;
Carvalho-Ferreira, Joana Pereira de;
Molin Netto, Bárbara Dal;
Clemente, Ana Paula Grotti;
Tock, Lian;
Tufik, Sergio;
Mello, Marco Túlio de;
Dâmaso, Ana Raimunda.
ABSTRACT Objectives: Obesity is a multifactorial disease characterized by the presence of the pro-inflammatory state associated with the development of many comorbidities, including bone turnover marker alterations. This study aimed to investigate the role of the inflammatory state on bone turnover mark...
Adiponectina/sangre,
Biomarcadores/sangre,
Índice de Masa Corporal,
Densidad Ósea,
Remodelación Ósea,
Terapia Combinada,
Dieta Reductora,
Terapia por Ejercicio,
Leptina/sangre,
Obesidad/sangre,
Obesidad/terapia,
Osteocalcina/sangre,
Entrenamiento de Fuerza,
Pérdida de Peso
ABSTRACT Objective Adipose tissue, particularly visceral adipose tissue, secretes a variety of cytokines, among which progranulin is a glycoprotein related to the immune system. Along with other secreted proteins, progranulin may be associated with bone mineral density. The aim of this study was to find...
Absorciometría de Fotón,
Tejido Adiposo/metabolismo,
Antropometría,
Composición Corporal,
Densidad Ósea/fisiología,
Proteína C-Reactiva/análisis,
Estudios Transversales,
Péptidos y Proteínas de Señalización Intercelular/sangre,
Interleucinas/sangre,
Lipoproteínas LDL/sangre,
Obesidad/sangre,
Osteoporosis/sangre,
Hormona Paratiroidea/sangre,
Progranulinas,
Valores de Referencia,
Factores Sexuales,
Factor de Necrosis Tumoral alfa/sangre,
Vitamina D/sangre
OBJECTIVES: To evaluate biomarkers associated with early cardiometabolic risk in obese adolescents. METHODS: This cross-sectional study included 137 adolescents of both sexes aged 10 to 19 years divided into a normal weight group (NW) (n=69) and an obese group (OB) (n=68). RESULTS: As expected, obesity...
Biomarcadores/sangre,
Índice de Masa Corporal,
Enfermedades Cardiovasculares/sangre,
Enfermedades Cardiovasculares/etiología,
Estudios de Casos y Controles,
Estudios Transversales,
Lipoproteínas LDL/sangre,
Obesidad/sangre,
Obesidad/complicaciones,
Factores de Riesgo,
Circunferencia de la Cintura
Castro, Adham do Amaral e;
Skare, Thelma Larocca;
Yamauchi, Fernando Ide;
Tachibana, Adriano;
Ribeiro, Suheyla Pollyana Pereira;
Fonseca, Eduardo Kaiser Ururahy Nunes;
Sakuma, Andressa Tamy;
Peixoto, Milena Rocha;
Rodrigues, Mariana Athaniel Silva;
Barreiros, Maria Angela M.
ABSTRACT Background: The C reactive protein (CRP) is one of the most accurate inflammatory markers in acute appendicitis (AA). Obesity leads to a pro-inflammatory state with increased CRP, which may interfere with the interpretation of this laboratory test in AA. Aim: To assess sensitivity, specifici...
Apendicitis/sangre,
Apendicitis/complicaciones,
Índice de Masa Corporal,
Proteína C-Reactiva/análisis,
Estudios de Casos y Controles,
Grasa Intraabdominal,
Obesidad/sangre,
Obesidad/complicaciones,
Valor Predictivo de las Pruebas,
Estudios Retrospectivos,
Sensibilidad y Especificidad
ABSTRACT Background : Obesity is one of the main causes of glycemic change. Failure of clinical obesity treatment may lead to an increase in bariatric surgery. Dietary guidance, in conjunction with disabsorptive and hormonal factors resulting from the anatomical and physiological changes provoked by the...
Glucemia/análisis,
Diabetes Mellitus Tipo 2/sangre,
Diabetes Mellitus Tipo 2/complicaciones,
Ingestión de Alimentos,
Derivación Gástrica,
Estudios Longitudinales,
Obesidad/sangre,
Obesidad/complicaciones,
Obesidad/metabolismo,
Obesidad/cirugía,
Estudios Retrospectivos,
Factores de Tiempo
ABSTRACT Background: PCR (C-reactive protein), produced in the liver after stimuli of inflammatory mediators, is determined as a marker of inflammatory activity (adipocytokines) and is present within adipocyte cells; besides being an inflammatory product, many studies have shown to be a predictor of com...
Proteína C-Reactiva/análisis,
Enfermedad Crónica,
Derivación Gástrica/métodos,
Inflamación/sangre,
Obesidad/sangre,
Obesidad/cirugía,
Periodo Posoperatorio,
Periodo Preoperatorio,
Estudios Prospectivos,
Valores de Referencia,
Factores de Tiempo,
Resultado del Tratamiento,
Pérdida de Peso/fisiología
ABSTRACT Objective: Thus, the aim of this study was to compare if higher or smaller fibronectin type 3 domain-containing protein 5 (FNDC5)/irisin levels are associated with inflammatory and metabolic markers, caloric/macronutrient intake, physical fitness and type 2 diabetes mellitus (T2DM) risk in obes...
Biomarcadores/sangre,
Presión Sanguínea/fisiología,
Capacidad Cardiovascular/fisiología,
Estudios Transversales,
Diabetes Mellitus Tipo 2/sangre,
Diabetes Mellitus Tipo 2/etiología,
Diabetes Mellitus Tipo 2/fisiopatología,
Ingestión de Energía/fisiología,
Prueba de Esfuerzo,
Fibronectinas/sangre,
Lipopolisacáridos/sangre,
Obesidad/sangre,
Obesidad/complicaciones,
Obesidad/fisiopatología,
Factores de Riesgo
ABSTRACT Objective: The aim of this study was to evaluate the association between insulin resistance and thyroid pathology in obese patients, and compare the results between insulin-resistant and noninsulin-resistant patients. Subjects and methods: Obese/nondiabetic patients, aged 18-70 years, attendin...
ABSTRACT Objective Adipokines are mediators of body composition and are involved in obesity complications. This study aimed to assess the association of circulating omentin-1, vaspin, and RBP-4 with body composition indices and metabolic health status (MHS) in different phenotypes of body size. Subjec...
Composición Corporal,
Índice de Masa Corporal,
Tamaño Corporal,
Estudios Transversales,
Citocinas/sangre,
Ensayo de Inmunoadsorción Enzimática,
Proteínas Ligadas a GPI/sangre,
Lectinas/sangre,
Obesidad/sangre,
Obesidad/metabolismo,
Fenotipo,
Proteínas Plasmáticas de Unión al Retinol/análisis,
Serpinas/sangre
ABSTRACT Objective This study aimed to investigate the association of plasma TNF-α, IL-6, and lL-10 levels and cytokine gene polymorphisms [TNF-α (-308 G→A), IL-6 (-174 C→G) and IL-10 (-1082 A→G, -819 T→C and -592 A→C)] in type 2 diabetes mellitus (T2DM) and obes...
Biomarcadores/sangre,
Índice de Masa Corporal,
Estudios de Casos y Controles,
Estudios Transversales,
Diabetes Mellitus Tipo 2/sangre,
Diabetes Mellitus Tipo 2/genética,
Frecuencia de los Genes,
Genotipo,
Interleucina-10/sangre,
Interleucina-10/genética,
Interleucina-6/genética,
Obesidad/sangre,
Obesidad/genética,
Reacción en Cadena de la Polimerasa,
Polimorfismo Genético,
Factor de Necrosis Tumoral alfa/sangre,
Factor de Necrosis Tumoral alfa/genética
