Abstract A few investigations of caries biofilms have identified Scardovia spp.; however, little is known about its involvement in caries pathogenesis. The purpose of this study was to assess the gene expression profile of Scardovia spp. in root caries, and compare it with other microorganisms. Clinical ...
Actinobacteria/genética,
Actinobacteria/aislamiento & purificación,
Biopelículas,
Mapeo Cromosómico,
ADN Bacteriano,
Perfilación de la Expresión Génica,
Expresión Génica,
Persona de Mediana Edad,
Valores de Referencia,
Caries Radicular/microbiología,
Análisis de Secuencia de ADN,
Estadísticas no Paramétricas,
Transcriptoma
BACKGROUND: Pigmentation development, is a complex process regulated by many transcription factors during development. With the development of the RNA sequencing (RNA-seq), non-coding RNAs, such as miRNAs, lncRNAs, and circRNAs, are found to play an important role in the function detection of related reg...
Myocardial ischemia/reperfusion (MI/R) injury is a complex phenomenon that causes severe damage to the myocardium. However, the potential molecular mechanisms of MI/R injury have not been fully clarified. We identified potential molecular mechanisms and therapeutic targets in MI/R injury through analysis...
Pereira, Leandro de Mattos;
Messias, Elisa Alves;
Sorroche, Bruna Pereira;
Oliveira, Angela das Neves;
Arantes, Lidia Maria Rebolho Batista;
Carvalho, Ana Carolina de;
Tanaka-Azevedo, Anita Mitico;
Grego, Kathleen Fernandes;
Carvalho, André Lopes;
Melendez, Matias Eliseo.
Lack of complete genomic data of Bothrops jararaca impedes molecular biology research focusing on biotechnological applications of venom gland components. Identification of full-length coding regions of genes is crucial for the correct molecular cloning design. Methods: RNA was extracted from the venom ...
BACKGROUND The leishmaniases are complex neglected diseases caused by protozoan parasites of the genus Leishmania. Leishmania braziliensis is the main etiological agent of cutaneous leishmaniasis in the New World. In recent studies, genomic changes such as chromosome and gene copy number variations (CNV...
García, Patricia;
Bizama, Carolina;
Rosa, Lorena;
Espinoza, Jaime A;
Weber, Helga;
Cerda-Infante, Javier;
Sánchez, Marianela;
Montecinos, Viviana P;
Lorenzo-Bermejo, Justo;
Boekstegers, Felix;
Dávila-López, Marcela;
Alfaro, Francisca;
Leiva-Acevedo, Claudia;
Parra, Zasha;
Romero, Diego;
Kato, Sumie;
Leal, Pamela;
Lagos, Marcela;
Roa, Juan Carlos.
BACKGROUND: Gallbladder cancer (GBC) is the most common tumor of the biliary tract. The incidence of GBC shows a large geographic variability, being particularly frequent in Native American populations. In Chile, GBC represents the second cause of cancer-related death among women. We describe here the es...
Antígenos de Carbohidratos Asociados a Tumores/genética,
Neoplasias de la Vesícula Biliar/genética,
Indígenas Sudamericanos/genética,
Antineoplásicos/farmacología,
Líquido Ascítico/metabolismo,
Carcinogénesis/genética,
Línea Celular Tumoral/efectos de los fármacos,
Línea Celular Tumoral/metabolismo,
Cisplatino/farmacología,
Células Clonales/efectos de los fármacos,
Células Clonales/metabolismo,
Desoxicitidina/análogos & derivados,
Desoxicitidina/farmacología,
Células Epiteliales/metabolismo,
Neoplasias de la Vesícula Biliar/metabolismo,
Genes erbB-2/genética,
Queratina-19/genética,
Queratina-7/genética,
Receptor ErbB-2/genética,
Proteína p53 Supresora de Tumor/genética,
Pruebas de Carcinogenicidad,
Chile,
Dermatoglifia del ADN,
Perfilación de la Expresión Génica,
Ratones Endogámicos NOD,
Análisis de Secuencia de ARN,
Células Tumorales Cultivadas
Abstract Cysticercus ovis or sheep measles is the larval stage of Taenia ovis, which is the intestinal tapeworm of dogs. It is found in the cardiac and skeletal muscles of sheep and can be the cause of partial or total condemnation of carcasses at abattoirs. The aim of the current work was to determine t...
Mataderos,
Cisticercosis/epidemiología,
Cisticercosis/veterinaria,
Cysticercus/genética,
Cysticercus/aislamiento & purificación,
Egipto/epidemiología,
Complejo IV de Transporte de Electrones/genética,
Perfilación de la Expresión Génica,
Filogenia,
Prevalencia,
Factores de Riesgo,
Ovinos/parasitología,
Enfermedades de las Ovejas/epidemiología,
Enfermedades de las Ovejas/parasitología
Abstract Synthetic polyploids are key breeding materials for watermelon. Compared with diploid watermelon, the tetraploid watermelon often exhibit wide phenotypic differences and differential gene expression. Digital gene expression (DGE) profile technique was performed in this study to present gene exp...
Introdução: Linfoma de Hodgkin (LH) é um dos linfomas mais frequentes no mundo ocidental, com cerca de 3 a 4 novos casos a cada 100 mil pessoas. Os microRNAs são pequenas moléculas que regulam a transcrição gênica e estão associadas ao desenvolvimento e progressão das neoplasias. Em LH clássic...
Pancreaticobiliary maljunction (PBM) is associated with high risk of epithelial atypical growth and malignant transformation of the bile duct or gallbladder. However, overall changes in genetic expression have not been examined in children with PBM. Genome-wide expression was analyzed using peripheral bl...
Neoplasias de los Conductos Biliares/etiología,
Conductos Biliares/anomalías,
Proteínas Portadoras/genética,
Estudios de Casos y Controles,
Dilatación Patológica/complicaciones,
Dilatación Patológica/congénito,
Fucosiltransferasas/genética,
Neoplasias de la Vesícula Biliar/etiología,
Perfilación de la Expresión Génica,
Análisis por Micromatrices,
Conductos Pancreáticos/anomalías,
Regulación hacia Arriba/genética
