Introducción: El cáncer gástrico constituye la segunda causa de muerte en la población mundial. En Cuba ocupa el octavo lugar. La etiología es multifactorial. La infección por Helicobacter pylori, el tipo de alimentación, la susceptibilidad genética y los antecedentes familiares son algunos de su...
SUMMARY The occurrence of fractures in young individuals is frequently overlooked by physicians, especially when associated with exercise or trauma. Nevertheless, multiple fractures should always be investigated since underlying conditions can predispose to such events. We describe here the case of a you...
ABSTRACT Objective: Globally developing metabolic syndrome (MetS) prevalence as a major health problem can be related to multiple factors of genetic and environmental. Dimethylaminohydrolase 2 (DDAH2) is the main enzyme implicated in the cardiovascular system, which regulates the nitric oxide pathway. T...
SUMMARY OBJECTIVE The aim of this study was to investigate whether TCF7L2 gene mutation rs7903146 is in association with polycystic ovary syndrome (PCOS). METHODS A total of 44 PCOS and 48 control participants were recruited for this study. After DNA extraction from peripheral blood, quantitative PCR m...
Abstract Objectives The study aimed to evaluate the link between the IL-4-C590T polymorphism and asthma susceptibility in children by meta-analysis. Sources The study collected all the case-control studies found in PubMed, Embase, CNKI, Wanfang, VIP, and other databases until September 2019. Stata v. 1...
RESUMEN La aerofagia es la estereotipia clásica más común en los equinos, con una etiología poca entendida; sin embargo, se reconoce por ser de naturaleza multifactorial. Además, se ha asociado con efectos negativos sobre la salud de los equinos portadores. El objetivo de este estudio fue describir ...
Pacheco-Romero, José;
Acosta, Oscar;
Huerta, Doris;
Cabrera, Santiago;
Vargas, Marlene;
Mascaro, Pedro;
Huamán, Moisés;
Sandoval, José;
López, Rudy;
Mateus, Julio;
Gil, Enrique;
Guevara, Enrique;
Butrica, Nitza;
Catari, Diana;
Bellido, David;
Custodio, Gina;
Naranjo, Andrea.
Abstract Background: Preeclampsia is a multiorgan disorder associated with maternal and perinatal morbi-mortality. In Peru, incidence is 10% and accounts for 22% of maternal deaths. Genome and genetic epidemiological studies have found an association between preeclampsia and genetic polymorphisms. Obj...
Preeclampsia,
Estudios de Casos y Controles,
Frecuencia de los Genes,
Marcadores Genéticos,
Predisposición Genética a la Enfermedad,
Genotipo,
Perú/epidemiología,
Polimorfismo de Nucleótido Simple,
Preeclampsia/epidemiología,
Preeclampsia/genética,
Factor A de Crecimiento Endotelial Vascular/genética
Introdução: O novo coronavírus causou uma pandemia e desafio na saúde pública em todo o mundo. Até hoje muitos mecanismos do vírus no hospedeiro foram desvendados, cujo conhecimento é essencial para entender a evolução clínica e desenvolver uma estratégia de terapia adequada para a infecção...
Estudios Retrospectivos,
COVID-19,
Coronavirus,
Enfermedades Raras,
Estrategias de Salud,
Evolución Clínica,
Inmunidad,
Infecciones,
Pacientes,
Predisposición Genética a la Enfermedad,
SARS-CoV-2,
Terapéutica,
Urticaria,
Vasculitis,
Síndrome de Dificultad Respiratoria
Abstract Matrix degradation is an important event in the progression, invasion and metastasis of malignant head and neck lesions. Imbalances, mutations and polymorphisms of MMPs and their inhibitors are observed in several cancer subtypes. The aim of this study was to evaluate the association of the MMP-...
