Abstract Malaria, a disease of public health concern is a known cause of kidney failure, and dependence on herbal medicines for its treatment is increasing due to the high cost of drugs. So this study is designed to evaluate the ameliorating effect of ethanol extract from Salacia nitida root bark on elec...
Salacia/efectos adversos,
Raíces de Plantas/efectos adversos,
Malaria/patología,
Electrólitos/agonistas,
Artesunato/antagonistas & inhibidores,
Costos y Análisis de Costo/clasificación,
d0041940,
Insuficiencia Renal/inducido químicamente,
d0018060,
Preparaciones Farmacéuticas/análisis,
d0145080
Abstract Chagas disease is a neglected parasitic disease caused by Trypanosoma cruzi, whose treatment has remained unsatisfactory for over 50 years, given that it is limited to two drugs. Benznidazole (BZN) is an efficient antichagasic drug used as the first choice, although its poor water-solubility, i...
Trypanosoma cruzi/aislamiento & purificación,
Enfermedades Desatendidas/clasificación,
Análisis Espectral/instrumentación,
Difracción de Rayos X/instrumentación,
Enfermedad de Chagas/patología,
Enfermedades Parasitarias/patología,
Esguinces y Distensiones/clasificación,
Espectroscopía Infrarroja por Transformada de Fourier/métodos,
Preparaciones Farmacéuticas/análisis,
d0129950,
Termogravimetría/métodos,
Técnicas In Vitro/métodos
Abstract Remifentanil is a modern fentanyl analogue with ultrashort-action granted by an esterase-labile methyl propanoate chain. Here, we present the development of a continuous flow methodology for the key N-alkylation step of remifentanil preparation in a biphasic, "slug-flow" regime. We screened para...
Abstract Epilepsy is a disorder of the central nervous system, in which the nerve cell activity in the brain is disturbed causing seizures. The objective was to develop an RP-HPLC method for consistent simultaneous quantitation of four antiepileptic drugs Levetiracetam (LVT), Lamotrigine (LTG), Phenobarb...
Abstract The aim of this study was to compare the dissolution properties of ibuprofen solid oral dosage forms commercially available in Bosnia and Herzegovina and to estimate the influence of dissolution medium composition on the drug release. Eight products (A-H) were subjected to in vitro dissolution t...
Abstract Over the years, a handful of drugs have been approved to be used in the fight against Alzheimer's Disease but unfortunately none of these drugs have proven to be solid-treatments. Alzheimer's Disease is one of the most prominent diseases observed in the elderly population. In this review article...
Abstract This study aimed to develop and evaluate the stability of sulfadiazine sugar-free extemporaneous oral suspensions, focusing on treating congenital toxoplasmosis. The excipients were carefully chosen to obtain safe products for the pediatric population. Sulfadiazine suspensions (100 mg/ mL) were ...
A doença de Chagas causada pelo parasita Trypanosoma cruzi acomete milhões de pessoas no mundo e não conta com um medicamento de ação efetiva para o seu tratamento etiológico. As drogas disponíveis, o nifurtimox e o benznidazol possuem índices de cura baixos com efeitos colaterais e toxidade que ...
O Diabetes Mellitus (DM) é uma doença crônica, que tem elevada prevalência na sociedade e representa um problema de saúde pública devido à natureza de suas complicações, acredita-se que a dificuldade na manutenção do tratamento, pode estar relacionada a deficiência ou falta de adesão. O estu...
Ejercicio Físico/fisiología,
Accesibilidad a los Servicios de Salud,
Atención Primaria de Salud/organización & administración,
Autocuidado/instrumentación,
Cumplimiento y Adherencia al Tratamiento,
Diabetes Mellitus/tratamiento farmacológico,
Enfermedad Crónica/tratamiento farmacológico,
Preparaciones Farmacéuticas/análisis,
Promoción de la Salud,
Salud Pública,
Sistema Único de Salud,
Quimioterapia,
Dieta Saludable,
Pacientes,
Diabetes Mellitus/diagnóstico,
Atención de Enfermería/métodos
Com o avanço da medicina e o aumento do uso de antimicrobianos, a resistência microbiana vem se tornando um problema sério na saúde pública. Para que uma bactéria se torne resistente, são necessários vários fatores, entre eles, o uso indiscriminado e prolongado de antimicrobianos e as resistênc...
Biopelículas/efectos de los fármacos,
Preparaciones Farmacéuticas/análisis,
Bacterias/efectos de los fármacos,
Antibacterianos/farmacología,
Antiinfecciosos/análisis,
Salud Pública,
Farmacorresistencia Bacteriana/efectos de los fármacos,
Farmacorresistencia Microbiana/efectos de los fármacos,
Resistencia a Medicamentos/efectos de los fármacos,
Pared Celular/efectos de los fármacos,
Bibliotecas Digitales,
Revisión
