The current study was conducted to determine the neuroprotective role and mechanism of action of Linalool (LIN) in SCI. The SCI in Sprague-Dawley (SD) rats was induced by weight-drop contusion model. Results of the suggested that LIN showed improvement in the locomo...
Monoterpenos Acíclicos/administración & dosificación,
Monoterpenos Acíclicos/farmacología,
Traumatismos de la Médula Espinal/tratamiento farmacológico,
Ratas Sprague-Dawley,
Estrés Oxidativo/efectos de los fármacos,
Inflamación,
Western Blotting,
FN-kappa B/antagonistas & inhibidores,
Receptor Toll-Like 4/antagonistas & inhibidores,
Transducción de Señal/efectos de los fármacos,
Ensayo de Inmunoadsorción Enzimática
El periodo postnatal temprano se caracteriza por rápido crecimiento cerebral, posiblemente relacionado con variaciones del oxígeno tisular. Esto ha motivado el estudio de protocolos que suministran diferentes concentraciones de oxígeno intermitentes, para observar sus efectos morfológicos y cerebrale...
Este estudio tuvo como objetivo demostrar la existencia de variaciones morfológicas en el tejido conectivo de la glándula submandibular de ratas obesas expuestas a glutamato monosódico (GMS). Se utilizaron 12 ratas Sprague Dawley machos recién nacidas (6 ratas para el grupo 1, control; 6 ratas para e...
SUMMARY: Paracetamol (known as acetaminophen, or APAP) poisoning causes acute liver damage that can lead to organ failure and death. We sought to determine that APAP overdose can augment tumor necrosis factor-alpha (TNF-α)/ nuclear factor kappa B (NF-kB)/induced nitic oxide synthase (iNOS) axis-medi...
Enfermedad Hepática Crónica Inducida por Sustancias y Drogas/tratamiento farmacológico,
Acetaminofén/toxicidad,
Quercetina/administración & dosificación,
Resveratrol/administración & dosificación,
Enfermedad Aguda,
Factor de Necrosis Tumoral alfa/antagonistas & inhibidores,
FN-kappa B/antagonistas & inhibidores,
Óxido Nítrico Sintasa/antagonistas & inhibidores,
Quimioterapia Combinada,
Sobredosis de Droga,
Ratas Sprague-Dawley,
Sustancias Protectoras
Purpose: It was aimed to investigate the biochemical and immunohistochemical effects of ephedrine (EPH) in bilateral ovariectomized rats. Methods: Twenty-four Sprague Dawley female rats were divided into three groups: control group: The abdomen was opened and closed without any treatment; ischemia-reperf...
Abstract Consuming a high-fat diet causes a harmful accumulation of fat in the liver, which may not reverse even after switching to a healthier diet. Different reports dealt with the role of purslane as an extract against high-fat diet; meanwhile, it was necessary to study the potential role of fresh pur...
Wu, Qiaoyun;
Cai, Chenchen;
Ying, Xinwang;
Zheng, Yujun;
Yu, Jiaying;
Gu, Xiaoxue;
Tu, Wenzhan;
Lou, Xinfa;
Yang, Guanhu;
Li, Ming;
Jiang, Songhe.
Previous studies have shown that peripheral nerve injury can lead to abnormal dendritic spine remodeling in spinal dorsal horn neurons. Inhibition of abnormal dendritic spine remodeling can relieve neuropathic pain. Electroacupuncture (EA) has a beneficial effect on the treatment of neuropathic pain, but...
Quintana Villar, Carlos;
Labarca Prado, Pedro;
Fresno Joannon, Ana María;
Cid Paz, Ricardo;
Cavagnaro Santa María, Felipe;
Guiraldes Camerati, Ernesto;
Quintana Fresno, Juan Carlos;
Bezanilla Mena, Felipe;
Wolf Zabalaga, Alex;
Accatino Locatelli, Luigi.
The intestine has a very important role in the homeostasis of the internal medium. Bile acids play a regulatory role in the digestion and absorption of nutrients. Among them, deoxycholic acid, when its luminal concentration increases due to bacterial overgrowth, modifies hydroelectrolytic transport, prod...
La mandíbula de rata es una de las estructuras anatómicas de mayor interés en la investigación en las ciencias odontológicas, esto debido a su similitud con la mandíbula humana. El objetivo de este estudio fue caracterizar morfometricamente la mandíbula de ratas mediante CBCT. Se analizó el exame...
SUMMARY: Diabetic nephropathy (DN) is the most common complication of diabetes. Several studies have been done in a trial to protect against this problem at the ultrastructure level. This study investigates the protective effect of oral administration of Acacia senegal (AS) against the development of DN....
