SUMMARY: The toxic effects of acetaminophen appear primarily in the liver and kidney. The protective effect of blue green alga Arthrospira platensis on hepato-renal toxicity caused by acetaminophen was evaluated in male rats. The obtained results showed that subcutaneous injection of acetaminophen at a d...
Hígado/efectos de los fármacos,
Riñón/efectos de los fármacos,
Acetaminofén/toxicidad,
Spirulina,
Preparaciones de Plantas/administración & dosificación,
Peroxidación de Lípido,
Alanina Transaminasa/análisis,
Fosfatasa Alcalina/análisis,
Aspartato Aminotransferasas/análisis,
Interleucinas,
Ratas Wistar,
Superóxido Dismutasa
SUMMARY: To evaluate the histological adverse effects of alendronate administered systemically and topically in combination with orthodontic movement by intense force. Thirty-six 24-week-old female Wistar rats, ovariectomized, were used and divided into three groups (n = 12/group): control, locally treat...
Maxilar/patología,
Conservadores de la Densidad Ósea/efectos adversos,
Alendronato/efectos adversos,
Técnicas de Movimiento Dental/instrumentación,
Métodos de Anclaje en Ortodoncia,
Ratas Wistar,
Análisis de Varianza,
Ovariectomía,
Resorción Ósea/inducido químicamente,
Inflamación/inducido químicamente,
d0041640
SUMMARY: The preserved form of all components of the nerve fiber is a prerequisite for the proper conduction of the nerve impulse. various factors can change the shape of nerve fibers. In everyday practice, qualitative histological analysis is the gold standard for detecting changes in shape. Geometric m...
SUMMARY: It is known that diabetes mellitus has late complications, including microvascular and macrovascular diseases. Diabetes can affect bones through biochemical markers of bone structure, density, and turnover. This study aimed to biomechanically investigate the bone-protective effects of angiotensi...
SUMMARY: Magnolia bark extract supplementation has an anti-oxidative role in mammalians. However, its role in physiological aged-associated heart insufficiency is not known yet. Therefore, we investigated the effects of a magnolia bark complex, including magnolol and honokiol components (MAHOC), in elder...
Amaral, Eduarda Carolina;
da Silva, Gustavo Ratti;
Braga, Fernanda de Abreu;
Palozi, Rhanany Alan Calloi;
Lorençone, Bethânia Rosa;
Marques, Aline Aparecida Macedo;
Moreno, Karyne Garcia Tafarelo;
Leite, Patrícia Regina Terço;
Barboza, Lorena Neris;
Souza, Roosevelt Isaias Carvalho;
dos Santos, Ariany Carvalho;
Lovato, Evellyn Claudia Wietzikoski;
Ribeiro-Paes, João Tadeu;
Junior, Arquimedes Gasparotto;
Lívero, Francislaine Aparecida dos Reis.
This study proposes an unpreceded model of cardiovascular disease by combining alcohol and energy drink intake with hookah smoking to investigate the cardiovascular effects of Baccharis trimera (Less.) DC., a medicinal plant used to treat dyslipidemia. For 10 weeks, Wistar rats (n=8) re...
The objective of this work was to evaluate the gastroprotective activity of the crude ethanolic extract (CEE) from the stem barks of Piptadenia viridiflora using the acute models of inducing gastric ulcers by ethanol, ethanol-acidified, and ischemia-reperfusion, and correlating thi...
SUMMARY: Changes in the microcirculation of multiple tissues and organs have been implicated as a possible mechanism in physiological aging. In particular, vascular endothelial growth factor is a secretory protein responsible for regulating angiogenesis via altering endothelial proliferation, survival, m...
Vasos Coronarios/fisiología,
Riñón/fisiología,
Riñón/irrigación sanguínea,
Microcirculación,
Envejecimiento,
Factores de Crecimiento Endotelial Vascular/metabolismo,
Capilares/anatomía & histología,
Vasos Coronarios/anatomía & histología,
Riñón/anatomía & histología,
Corazón/anatomía & histología,
Corazón/fisiología,
Inmunohistoquímica,
Técnica del Anticuerpo Fluorescente,
Ratas Wistar
SUMMARY: Cadmium (Cd) is the industrial and environmental toxic heavy metal which is found in air, water and soil. Cd, adversely affects many organs in humans such as kidney, intestine, liver, testis and lungs. L-carnitine (LC) is an important agent that plays essential role in energy metabolism. In our ...
SUMMARY: Rheumatoid arthritis (RA) that affects the synovial knee joint causes swelling of the synovial membrane and tissue damage. Interleukin-17A (IL-17A) and the enzyme glycogen synthase kinase-3β (GSK3β) are involved in the pathogenesis of RA. The link between IL-17A, GSK3β, the oxidat...
Artritis Reumatoide,
Tiadiazoles/administración & dosificación,
Interleucina-17,
Modelos Animales de Enfermedad,
Glucógeno Sintasa Quinasa 3 beta,
Fibrosis,
Especies Reactivas de Oxígeno,
Actinas,
Ratas Wistar,
Western Blotting,
Colágeno Tipo II/administración & dosificación,
Inmunohistoquímica,
d0077190,
d0154150,
Inmunización
