Background Although classical human T-cell lymphocyte virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis syndrome is the most frequent HTLV-1-associated neurological disorder, some "minor" neurological disorders can be seen in "asymptomatic" carriers. These disorders, including cog...
Análisis de Varianza,
Estudios de Casos y Controles,
Disfunción Cognitiva/fisiopatología,
Disfunción Cognitiva/virología,
Estudios Transversales,
Escolaridad,
Infecciones por HTLV-I/fisiopatología,
Infecciones por HTLV-I/psicología,
Trastornos de la Memoria/fisiopatología,
Trastornos de la Memoria/virología,
Pruebas Neuropsicológicas,
Valores de Referencia,
Estadísticas no Paramétricas,
Encuestas y Cuestionarios
Objective: In schizophrenia, scores reflecting deficits in different cognitive processes are strongly correlated, making it difficult to establish a solid relationship between different cognitive mechanisms and other features of this disorder. The objective of this study was to explore whether three freq...
Abstract We evaluated the involvement of the serotonergic system on memory formation and learning processes in healthy adults Wistar rats. Fifty-seven rats of 5 groups had one serotonergic nuclei damaged by an electric current. Electrolytic lesion was carried out using a continuous current of 2mA during ...
Conducta Animal,
Modelos Animales de Enfermedad,
Hipocampo/lesiones,
Hipocampo/fisiopatología,
Aprendizaje,
Aprendizaje por Laberinto,
Memoria,
Trastornos de la Memoria/fisiopatología,
Plasticidad Neuronal,
Ratas Wistar,
Neuronas Serotoninérgicas
Boa, Izadora Nogueira Fonte;
Rimkus, Carolina de Medeiros;
Campanholo, Kenia Repiso;
Pereira, Samira Luisa Apóstolos;
Junqueira, Thiago de Faria;
Machado, Melissa de Almeida Rodrigues;
Callegaro, Dagoberto;
Otaduy, Maria Concepción García;
Leite, Claudia da Costa;
Miotto, Eliane Correa.
ABSTRACT Objective: A 4.5-year follow-up study was conducted to characterize baseline verbal episodic memory (VEM) and its behavior and to assess the effects of relapsing-remitting multiple sclerosis (RRMS) on this domain. Methods: Twenty-nine patients with RRMS underwent two neuropsychological assessm...
ABSTRACT The present study investigated the effects of carvacrol on motor and memory deficits as well as hyperalgesia in the 6-OHDA-lesioned rat model of Parkinson's disease. The animals were subjected to unilateral microinjection of 6-OHDA into the medial forebrain bundle and treated with carvacrol (25,...
Antioxidantes/farmacología,
Antioxidantes/uso terapéutico,
Antiparkinsonianos/farmacología,
Antiparkinsonianos/uso terapéutico,
Cimenos,
Modelos Animales de Enfermedad,
Peroxidación de Lípido/efectos de los fármacos,
Trastornos de la Memoria/tratamiento farmacológico,
Trastornos de la Memoria/fisiopatología,
Memoria a Corto Plazo/efectos de los fármacos,
Monoterpenos/farmacología,
Monoterpenos/uso terapéutico,
Actividad Motora/efectos de los fármacos,
Neuralgia/tratamiento farmacológico,
Neuralgia/fisiopatología,
Oxidopamina,
Enfermedad de Parkinson/tratamiento farmacológico,
Enfermedad de Parkinson/fisiopatología,
Distribución Aleatoria,
Ratas Wistar,
Reproducibilidad de los Resultados,
Compuestos de Sulfhidrilo/análisis
ABSTRACT In this study, the effect of thymoquinone (TQ) on propylthiouracil (PTU)-induced memory impairment was investigated in juvenile rats. The rats were grouped into control, Hypo, Hypo-TQ5 and Hypo-TQ10. Propylthiouracil increased latency time in the Morris water maze test and decreased delay in ent...
Antioxidantes/farmacología,
Antitiroideos,
Reacción de Prevención/efectos de los fármacos,
Benzoquinonas/farmacología,
Lesiones Encefálicas/metabolismo,
Catalasa/análisis,
Modelos Animales de Enfermedad,
Hipocampo/efectos de los fármacos,
Hipotiroidismo/inducido químicamente,
Hipotiroidismo/complicaciones,
Discapacidades para el Aprendizaje/inducido químicamente,
Discapacidades para el Aprendizaje/tratamiento farmacológico,
Malondialdehído/análisis,
Aprendizaje por Laberinto/efectos de los fármacos,
Trastornos de la Memoria/inducido químicamente,
Trastornos de la Memoria/tratamiento farmacológico,
Óxido Nítrico/análisis,
Estrés Oxidativo/efectos de los fármacos,
Propiltiouracilo,
Ratas Wistar,
Superóxido Dismutasa/análisis
ABSTRACT OBJECTIVE To investigate macroregional variations in cognitive function in a national sample representative of the Brazilian population aged 50 years and older. METHODS Data from the baseline of the Longitudinal Study of Brazilian Elderly (ELSI-Brazil), collected between 2015 and 2016, were ...
Brasil/epidemiología,
Cognición/fisiología,
Escolaridad,
Estudios Longitudinales,
Trastornos de la Memoria/diagnóstico,
Trastornos de la Memoria/epidemiología,
Trastornos de la Memoria/fisiopatología,
Persona de Mediana Edad,
Pruebas Neuropsicológicas,
Población Rural,
Población Urbana
Resende, Elisa de Paula França;
Tovar-Moll, Fernanda Freire;
Ferreira, Fernanda Meireles;
Bramati, Ivanei;
Souza, Leonardo Cruz de;
Carmona, Karoline Carvalho;
Guimarães, Henrique Cerqueira;
Carvalho, Viviane Amaral;
Barbosa, Maira Tonidandel;
Caramelli, Paulo.
ABSTRACT The low-educated elderly are a vulnerable population in whom studying the role of white matter integrity on memory may provide insights for understanding how memory declines with aging and disease. Methods: Thirty-one participants (22 women), 23 cognitively healthy and eight with cognitive impa...
ABSTRACT Objective: to verify the correlation between health condition and memory performance of older adult women in the community. Method: Analytical cross-sectional study developed with 28 older adult women living in Cuiabá-MT. They answered the Mini-Mental State Examination (MMSE), and a shortened...
Estudios Transversales,
Depresión/complicaciones,
Depresión/epidemiología,
Depresión/etiología,
Estado de Salud,
Trastornos de la Memoria/epidemiología,
Persona de Mediana Edad,
Pruebas Neuropsicológicas,
Psicometría/instrumentación,
Psicometría/métodos,
Encuestas y Cuestionarios
Objective: Memory impairment is an important contributor to the reduction in quality of life experienced by older adults, and genetic risk factors seem to contribute to variance in age-related cognitive decline. Brain-derived neurotrophic factor (BDNF) is an important nerve growth factor linked with deve...
Factores de Edad,
Alelos,
Factor Neurotrófico Derivado del Encéfalo/genética,
Predisposición Genética a la Enfermedad,
Trastornos de la Memoria/genética,
Metionina/genética,
Análisis Multivariante,
Pruebas Neuropsicológicas,
Polimorfismo de Nucleótido Simple,
Factores de Riesgo,
Estadísticas no Paramétricas,
Análisis y Desempeño de Tareas,
Valina/genética,
Escalas de Wechsler
