Although studies suggest adverse effects of pesticides, human exposure to insecticides in homes is increasing and reports on their health effects are limited. The study investigated nephrotoxic effects of organo phosphate and carbamate insecticides, DD-Force and Baygon, in albino rats. Forty-fiv...
Summary Objective: To evaluate the levels of glycated hemoglobin (HbA1c) in patients heterozygous for hemoglobin variants and compare the results of this test with those of a control group. Method: This was an experimental study based on the comparison of HbA1c tests in two different populations, with ...
Bilirrubina/sangre,
Glucemia/análisis,
Estudios de Casos y Controles,
Cromatografía Líquida de Alta Presión,
Ayuno,
Hemoglobina Glucada/análisis,
Hemoglobina Glucada/genética,
Hemoglobinas Anormales/análisis,
Hemoglobinas Anormales/genética,
Heterocigoto,
Valores de Referencia,
Triglicéridos/sangre,
Urea/sangre
ABSTRACT PURPOSE: To characterize an experimental model of progressive renal disease induced by different degrees of nephrectomy in rats. METHODS: Eighty male Wistar rats were divided into four experimental groups (n=20/group): sham surgery (control group), progressive degrees of nephrectomy leading to...
Fallo Renal Crónico/fisiopatología,
Riñón/fisiopatología,
Nefrectomía/efectos adversos,
Uremia/metabolismo,
Albuminuria/sangre,
Presión Arterial/fisiología,
Creatinina/sangre,
Modelos Animales de Enfermedad,
Progresión de la Enfermedad,
Tasa de Filtración Glomerular/fisiología,
Fallo Renal Crónico/patología,
Nefrectomía/métodos,
Ratas Wistar,
Índice de Severidad de la Enfermedad,
Urea/sangre,
Uremia/etiología
ABSTRACT PURPOSE: To compare the two lines suture (total and seromuscular) after partial gastrectomy in normal and overweight rats. METHODS: Forty Wistar rats were distributed in two groups. Group A received normal diet; group B, normal diet and supplementation with saccharose in the water. When group ...
Gastrectomía/métodos,
Sobrepeso/cirugía,
Técnicas de Sutura,
Cicatrización de Heridas,
Bilirrubina/sangre,
Colesterol/sangre,
Laparotomía/métodos,
Periodo Posoperatorio,
Ratas Wistar,
Valores de Referencia,
Albúmina Sérica/análisis,
Factores de Tiempo,
Resultado del Tratamiento,
Urea/sangre
ABSTRACT PURPOSE: To evaluate the effect of the aqueous extract of the Vigna angularis, popularly known as "Azuki beans", in rats subjected to an experimental model of moderate chronic kidney disease. METHODS: Thirty rats underwent two surgeries - Ormrod and Miller (1980) - to obtain Moderate Chronic...
Nogueira, Glaucia R;
Azevedo, Paula S;
Polegato, Bertha F;
Zornoff, Leonardo AM;
Paiva, Sergio AR;
Nogueira, Celia R;
Araujo, Natalia C;
Carmona, Bruno HM;
Conde, Sandro J;
Minicucci, Marcos F.
OBJECTIVE: The aim of this study was to evaluate the roles of the Taql and Bsml vitamin D receptor gene polymorphisms in hospital mortality of burn patients. METHODS: In total, 105 consecutive burn injury patients over 18 years in age who were admitted to the Burn Unit of Bauru State Hospital from Janua...
Quemaduras/genética,
Quemaduras/mortalidad,
Creatinina/sangre,
Genotipo,
Mortalidad Hospitalaria,
Tiempo de Internación,
Modelos Logísticos,
Análisis Multivariante,
Polimorfismo Genético,
Potasio/sangre,
Estudios Prospectivos,
Receptores de Calcitriol/genética,
Factores de Riesgo,
Albúmina Sérica,
Sodio/sangre,
Urea/sangre
Background: Renal function declines according to age and vascular risk factors, whereas few data are available regarding geneticallymediated effects of anti-hypertensives over renal function. Objective: To estimate urea and creatinine variations in dementia due to Alzheimer disease (AD) by way of a pharm...
Enfermedad de Alzheimer/Sangre,
Inhibidores de la Enzima Convertidora de Angiotensina/farmacología,
Creatinina/Sangre,
Peptidil-Dipeptidasa A/genética,
Urea/Sangre,
Factores de Edad,
Alelos,
Presión Sanguínea/efectos de los fármacos,
Presión Sanguínea/genética,
Ayuno/Sangre,
Frecuencia de los Genes,
Genotipo,
Hipertensión/tratamiento farmacológico,
Hipertensión/genética
There is no standardization in the literature of kidney length in sheep at different ages, as there are few studies about the access with the Doppler triplex ultrasound for the renal vascularization in this species. Eighty healthy sheep of three age groups of Ile de France and White Dorper breed were use...
ABSTRACT PURPOSE: To evaluate the effect of Otostegia persica (O. persica) extract on renal damage induced by ischemia/reperfusion (I/R) in diabetic rats. METHODS: Forty-eight rats were subjected to right nephrectomy; then, they were allocated into six groups: Sham; Diabetic sham; I/R; Diabetic I/R; I/...
Antioxidantes/farmacología,
Diabetes Mellitus Experimental/complicaciones,
Lamiaceae,
Extractos Vegetales/farmacología,
Daño por Reperfusión/complicaciones,
Glucemia/efectos de los fármacos,
Catalasa/metabolismo,
Creatinina/sangre,
Hipoglucemiantes/farmacología,
Riñón/efectos de los fármacos,
Peróxidos Lipídicos/metabolismo,
Modelos Animales,
Nefrectomía/efectos adversos,
Estrés Oxidativo/efectos de los fármacos,
Peroxidasa/metabolismo,
Ratas Wistar,
Daño por Reperfusión/metabolismo,
Superóxido Dismutasa/metabolismo,
Urea/sangre
ABSTRACT PURPOSE: To evaluate the renal function and the renal histological alterations through the stereology and morphometrics in rats submitted to the natural process of aging. METHODS: Seventy two Wistar rats, divided in six groups. Each group was sacrificed in a different age: 3, 6, 9, 12, 18 and...
