Fernández-Rodarte, Bernardo A;
Soto-Domínguez, Adolfo;
González-Navarro, Alejandro;
Mellado-Ayala, Maximiliano;
Piña-Mendoza, Edgar I;
Rodríguez-Rocha, Humberto;
Montes-de-Oca-Luna, Roberto;
Guerra-Leal, Jesús D;
Guzmán-López, Santos;
Elizondo-Omaña, Rodrigo E.
SUMMARY: Reactive Oxygen Species (ROS) are part of the functional balance of various systems, they can generate cellular damage by oxidative stress associated with disease processes such as atherosclerosis, cardiovascular disease, diabetes, and aging. Some studies report that copper induces damage to the...
SUMMARY: Induction of osteoarthritis (OA) following diabetes is characterized by a sever inflammation of the joints that can lead to disability. The cartilage content of proteoglycans can substantially be reduced, following the induction of diabetes mellitus associated with inflammation as well as knee j...
SUMMARY: This study aims to investigate the effect of Tangzhouling on the morphological changes of Nissl bodies in the dorsal root ganglion of DM Rats. In this study, 69 rats were randomly divided into a control group (n = 10) and a model group (n = 59). The rats in the model group were randomly divided ...
SUMMARY: Skeletal muscle injury is an acute inflammatory condition caused by an inflammatory response. To reduce inflammatory cell infiltration and relieve skeletal muscle injury, efficient treatment is urgently needed. Nitric oxide is a free radical molecule reported to have anti-inflammatory effects. I...
Óxido Nítrico/farmacología,
Antiinflamatorios/farmacología,
Enfermedades Musculares/inducido químicamente,
Venenos Elapídicos/toxicidad,
Mioblastos/efectos de los fármacos,
Supervivencia Celular,
Ratas Sprague-Dawley,
Modelos Animales de Enfermedad,
Inmunohistoquímica,
Ensayo de Inmunoadsorción Enzimática,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Inflamación,
NG-Nitroarginina Metil Éster,
Caspasas,
Técnicas In Vitro
SUMMARY: Carbon tetrachloride (CCl4) is a manufactured chemical and does not occur naturally in the environment. CCl4 is a clear liquid that evaporates very easily. It has a sweet odor. CCl4 is toxic to the mammalian liver and is hepatocarcinogenic in both rats and mice. Rosemary (Rosmarinus Officinalis)...
Enfermedad Hepática Inducida por Sustancias y Drogas/tratamiento farmacológico,
Cinamatos/administración & dosificación,
Depsidos/administración & dosificación,
Antioxidantes/administración & dosificación,
Tetracloruro de Carbono/toxicidad,
Inmunohistoquímica,
Estrés Oxidativo/efectos de los fármacos,
Microscopía Electrónica de Transmisión,
Cinamatos/farmacología,
Depsidos/farmacología,
Antioxidantes/farmacología,
Malondialdehído/análisis,
Glutatión Peroxidasa/análisis,
Superóxido Dismutasa/análisis
SUMMARY: Osteoporosis is a bone condition marked by a loss of bone mass and a disruption of bone microarchitecture. Men lose bone density as they age, resulting in brittle bones. The loss of free testosterone is one of the key factors. The objective of present study was to evaluate Allolobophora caligino...
Oligoquetos,
Extractos de Tejidos/administración & dosificación,
Extractos de Tejidos/farmacología,
Osteoporosis/tratamiento farmacológico,
Orquiectomía/efectos adversos,
Apoptosis/efectos de los fármacos,
Ratas Wistar,
Inmunohistoquímica,
Osteoporosis/etiología,
Osteoporosis/prevención & control,
Huesos/efectos de los fármacos
SUMMARY: Rheumatoid arthritis (RA), an inflammatory autoimmune disease that causes cartilage degradation and tissue destruction, can affect synovial joints such as the knee joint. The link between the nitrosative stress enzyme inducible nitric oxide synthase (iNOS) and the cytokine interleukin-1 (IL-1 ...
Artritis Reumatoide/inmunología,
Glucógeno Sintasa Quinasa 3 beta/antagonistas & inhibidores,
Tiadiazoles/administración & dosificación,
Glucógeno Sintasa Quinasa 3 beta/administración & dosificación,
Estrés Nitrosativo/efectos de los fármacos,
Interleucina-1beta,
Colágeno Tipo II/administración & dosificación,
Ratas Wistar,
Artritis Reumatoide/inducido químicamente,
Inmunohistoquímica,
Modelos Animales de Enfermedad,
Inflamación
SUMMARY: Carnosine is known as a natural dipeptide, which inhibits the proliferation of tumor cells throughout its action on mitochondrial respiration and cell glycolysis. However, not much is known about its effects on the metabolism of healthy cells. We explored the effects of Karnozin EXTRA® capsule ...
Carnosina/farmacología,
Fibroblastos/efectos de los fármacos,
Riñón/citología,
Supervivencia Celular/efectos de los fármacos,
Metabolismo Energético,
Vimentina/efectos de los fármacos,
Superóxido Dismutasa/efectos de los fármacos,
Técnicas de Cultivo de Célula,
Bioensayo,
Técnica del Anticuerpo Fluorescente,
Cricetinae
SUMMARY: Laser photobiomodulation (laser PBM) is known to be able to accelerate burn wound healing in the animal model; however little evidence exists on the action of laser PBM on the expression of important proteins in wound healing in the animal model, such as VEGF and TGF-ß1. The aim of this study w...
INTRODUCCIÓN: El molnupiravir (EIDD-2801 o MK-4482-013) es un profármaco de un análogo de ribonucleósido antivírico, que se administra por vía oral, tiene actividad contra el SARS-CoV-2 in vitro, y que se encuentra actualmente bajo investigación para su uso en COVID-19. Actualmente la Administraci...
