Results: 952

Establishment of a simple and efficient platform for car-t cell generation and expansion: from lentiviral production to in vivo studies

ABSTRACT Introduction: Adoptive transfer of T cells expressing a CD19-specific chimeric antigen receptor (CAR) has shown impressive response rates for the treatment of CD19 + B-cell malignancies in numerous clinical trials. The CAR molecule, which recognizes cell-surface tumor-associated antigen indepen...

Comparison of the retention of conventional dentures after the use of common adhesive brands on poor denture foundations: an in vitro study

There is no information about the possible impact in denture retention after the use of common denture adhesives (DAs) when poor denture foundations (PDF) are present. Moreover, there is a lack of information about which current formulation provides greater retention and for how long. Twelve models from ...

Saccharomyces cerevisiae as a probiotic agent and a possible aflatoxin B1 adsorbent in simulated fish intestinal tract conditions

The aim of this study was to evaluate in vitro the probiotic potential and absorption of Saccharomyces cerevisiae for the aflatoxin B1 in simulated fish intestinal tract conditions. Three yeast strains were used, two from brewery: S. cerevisiae RC1 and S. cerevisiae RC3 and one from a fish farming enviro...

Atividade antagonista in vitro de bactérias ácido láticas isoladas de queijo de coalho artesanal do Sertão paraibano frente a microrganismos indicadores

Semina cienc. biol. saude; 41 (2, Supl.), 2020
Bactérias ácido láticas (BAL) produzem substâncias inibitórias de patógenos e deteriorantes de alimentos e isso tem despertado interesse sobre seu uso na preservação e na segurança sanitária desses produtos. Assim, o estudo foi realizado com o objetivo de avaliar a atividade inibitória de Stre...

Evaluation of anti-biofouling potential of Viburnum opulus extracts

In this study the in vitro investigation of the inhibitory effect of ethanol extract of Viburnum opulus L. bark sample on Streptococcus mutans planctonic cells and biofilm has been intended. A Scanning electron microscopy analysis has been performed in order to investigate the inhibitory effect of the ex...

The correlation between micronuclei count and smoking behavior: a hospital-based study

J. oral res. (Impresa); 9 (2), 2020
Background: Micronucleus is a microscopically visible cyto-plasmic chromatin mass in the extranuclear vicinity, originating from aberrant mitosis, which consists of eccentric chromosomes that have failed to reach spindle poles during mitosis. The present study was designed to evaluate and compare cytogen...

Estudio de la bioaccesibilidad in vitro de zinc en arroz (oryza sativa) y su relación con el contenido de ácido fitico

Rev. chil. nutr; 47 (2), 2020
La bioaccesibilidad de un nutriente en un alimento sirve para determinar la calidad nutricional de éste para el consumo humano. El arroz es uno de los alimentos más importantes en la dieta por su gran aporte calórico y nutricional. El objetivo de este estudio fue analizar la bioaccesibilidad in vitro ...

Remineralizing Effect of Xilitol, Juniperus Communis and Camellia Sinensis Added to a Toothpaste: An In Vitro Study

Odovtos (En línea); 22 (1), 2020
ABSTRACT The aim of this study was to explore the remineralizing effect of toothpastes based on Xilitol, Camellia Sinensis and Juniperus Communis. An in vitro experimental study was carried out in an 18 human premolars sample, which were treated with one of the 3 evaluated toothpastes and a control fluor...

Comparação de diferentes métodos de inserção da pasta de hidróxido de cálcio para preenchimento de canais laterais simulados: estudo in vitro
Comparison of different methods for insertion of calcium hydroxide paste in the filling of simulated lateral canals: in vitro evaluation

Dent. press endod; 10 (1), 2020
Avaliar, em micro-CT, diferentes métodos de inserção da pasta de hidróxido de cálcio para preenchimento de canais laterais simulados em blocos de acrílico. Métodos: Foram utilizados 72 blocos de acrílico com canais laterais simuladas nas porções cervical, média e apical, os quais foram preench...

Composição química e cinética de degradação ruminal in vitro de aveia branca cv. URS guapa sob diferentes níveis de adubação nitrogenada

Avaliaram-se as doses de nitrogênio 0, 60, 120 e 240kg ha-1 sobre a composição bromatológica e os parâmetros da cinética de degradação ruminal da aveia branca obtida de dois anos de cultivo (2013-2014). Foram realizadas as análises de matéria seca, matéria mineral (MM), proteína bruta (PB), e...