Results: 3070

Evaluación de la experiencia terapeútica con enoxacina en retratamiento de la tuberculosis pulmonar

Se trató 30 pacientes con diagnóstico de tuberculosis pulmonar con esquema de retratamiento que incluían Enoxacina en el Programa de Control de TBC del Hospital Nacional Cayetano Heredia y centros relacionados en Lima, Perú desde 1988. Los cuales recibieron el fármaco por razones humanitarias a una ...

Chemical and pharmacological investigation of Solanum species of Brazil: a search for solasodine and other potentially useful therapeutic agents

Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991
A systematic search for solasodine, an important staring material for the partial synthesis of steroidal hormones as well as other potentially bioactive constituents of various Solanum species of Brazil has been undertaken. Thus, the fruits of S. paludosum, S. asperum, S. sessiliforum and Solanum sp. wer...

Sesquiterpene lactones from Vernonia

Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991
Some informations about the sesquiterpene lactones isolated from Brazilian species of Vernonia are described, as well the results of tests developed with such compounds with respect to their anti-feedant, molluscicide, antimicrobial and analgesic properties....

Bioactive glycosides from Chinese medicines

Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991
Glycosides are the bioactive components of many famous Chinese medicines. Here reported are some bioactive glycosides we discovered from Chinese medicines in recent years. (1) Pheolic glycosides from Chinese medicines: Gastrodia elata, acontium austroynanense and Helicia erratica, three bioactive phenoli...

Cardiac glycosides isolated from the Indian-snuff, Maquira sclerophylla Ducke

Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991
The hydroalcoholic extract of the powdered bark of the Indian-snuff Maquira sclerophylla Ducke was purified by column chromatography in silica-gel and the major cardenolide isolated from preparative TLC was identified by 1H-NMR, 1 2 C-NMR and IR analyses. The spectra showed that the active substance has ...

Evaluation of acute administration of natural products with potential diuretic effects, in humans

Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991
In order to evaluate the potential diuretic effect of two natural products, Elephantopus scaber and Alpinia speciosa, a trial administration was carried out in ten healthy volunteers and the effects compared to the those of a placebo. The substances were given on different days, with a seven day interval...

Plant lectins, chemical and biological aspects

Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991
Lectins, carbohydrate-binding proteins of non-immune origin, that agglutinate cells or precipitate polysaccharides and glycoconjugates, are well distributed in nature, mainly in the Plant Kingdom. The great majority of the plante lectins are present in seed cotyledons where they are found in the cytoplas...

Some progress on the chemistry of natural bioactive terpenoids form Chinese medicinal plants

Mem. Inst. Oswaldo Cruz; 86 (supl.2), 1991
(1) Pseudolaric acids - Novel diterpenes, Pseudolaric acid A, B, C and D were isolated from Pseudolarix kaempferi Gorden (pinaceae). Their structures were assigned by spectroscopic data and chemical correlations. In the contineous studies, the absolute configurations, the conformations in the solutions, ...