Results: 5034

El uso combinado de terlipresina más albúmina es más efectivo que la albúmina por sí sola en mejorar la función renal en pacientes con cirrosis y síndrome hepatorrenal tipo 1

Gastroenterol. latinoam; 28 (3), 2017

BJ-1108, a 6-Amino-2,4,5-trimethylpyridin-3-ol analogue, regulates differentiation of Th1 and Th17 cells to ameliorate experimental autoimmune encephalomyelitis

Biol. Res; 50 (), 2017
BACKGROUND: CD4+ T cells play an important role in the initiation of an immune response by providing help to other cells. Among the helper T subsets, interferon-γ (IFN-γ)-secreting T helper 1 (Th1) and IL-17-secreting T helper 17 (Th17) cells are indispensable for clearance of intracellular as well as ...

Alpinia oxyphylla Miq. extract changes miRNA expression profiles in db-/db- mouse kidney

Biol. Res; 50 (), 2017
BACKGROUND: A number of dysregulated miRNAs have been identified and are proposed to have significant roles in the pathogenesis of type 2 diabetes mellitus or renal pathology. Alpinia oxyphylla has shown significant anti-inflammatory properties and play an anti-diabetes role. The objective of this study ...

Does Cimicifuga racemosa have the effects like estrogen on the sublingual gland in ovariectomized rats?

Biol. Res; 50 (), 2017
BACKGROUND: Cimicifuga racemosa is one of the herbs used for the treatment of climacteric syndrome, and it has been cited as an alternative therapy to estrogen. Apart from hectic fevers, dyspareunia and so on, dry mouth also increase significantly after menopause. It has not yet been reported whether C. ...

De novo transcriptome assembly, functional annotation and differential gene expression analysis of juvenile and adult E. fetida, a model oligochaete used in ecotoxicological studies

Biol. Res; 50 (), 2017
BACKGROUND: Earthworms are sensitive to toxic chemicals present in the soil and so are useful indicator organisms for soil health. Eisenia fetida are commonly used in ecotoxicological studies; therefore the assembly of a baseline transcriptome is important for subsequent analyses exploring the impact of ...

A spleen tyrosine kinase inhibitor attenuates the proliferation and migration of vascular smooth muscle cells

Biol. Res; 50 (), 2017
BACKGROUND: Pathologic vascular smooth muscle cell (VSMC) proliferation and migration after vascular injury promotes the development of occlusive vascular disease. Therefore, an effective chemical agent to suppress aberrant proliferation and migration of VSMCs can be a potential therapeutic modality for ...

Properties of realgar bioleaching using an extremely acidophilic bacterium and its antitumor mechanism as an anticancer agent

Biol. Res; 50 (), 2017
Realgar is a naturally occurring arsenic sulfide (or Xionghuang, in Chinese). It contains over 90% tetra-arsenic tetrasulfide (As4S4). Currently, realgar has been confirmed the antitumor activities, both in vitro and in vivo, of realgar extracted using Acidithiobacillus ferrooxidans (A. ferrooxidans). Bi...

Espironolactona aumenta los niveles circulantes de angiotensina-(1-9) y revierte el remodelado cardíaco en la hipertensión arterial experimental

Rev. chil. cardiol; 36 (2), 2017
Previamente hemos demostrado que la eficacia de enalapril, candesartán y de fasudil -inhibidor de la vía RhoA/ROCK,- en el tratamiento del remodelado cardíaco en la hipertensión (HTA) e infarto al miocardio está mediada por aumento en los niveles circulantes del péptido vasoactivo angiotensina [Ang...

Efecto de Maytenus krukovii “Chuchuhuasi” en el tratamiento de osteoartrosis leve-moderada. Ensayo clínico aleatorizado doble-ciego, controlado con placebo
Safety and efficacy of Maytenus krukovii “Chuchuhuasi” decoction in mild to moderate osteoarthritis. A 4-week randomized double-blind placebo-controlled clinical trial

Rev. peru. med. integr; 2 (1), 2017
Objetivo: Evaluar la seguridad y eficacia de Maytenus krukovii "chuchuhuasi" a diferentes dosis en pacientes con osteoartrosis leve-moderada. Materiales y Métodos: Ensayo clínico aleatorizado, doble ciego. Se incluyeron a 50 pacientes con osteoartrosis leve-moderada (clasificación de Kellgren-Lawrence...

Actividad inmunoestimulante del extracto acuoso liofilizado de la planta entera de Physalis angulata L. en ratas albinas cepa Holtzman
Immunoestimulant activity of Physalis angulata L whole plant-lyophilized aqueous extract in albino Holtzman rats

Rev. peru. med. integr; 2 (1), 2017
Objetivo: Evaluar la actividad inmunoestimulante del extracto acuoso liofilizado (EAL) de la planta entera de Physalis angulata L. “bolsa mullaca”. Materiales y Métodos: Se usaron 32 ratas albinas divididas en cuatro grupos: agua destilada 3 mL (control); Metisopinol (Isoprinosine) 14.7 mg/Kg; EAL P...