O conceito de 'raça' faz parte do arcabouço canônico da medicina, associado à idéia de que cor e/ou ancestralidade biológica são relevantes como indicadores de predisposição a doenças ou de resposta a fármacos. Essa posição decorre de uma visão tipológica de raças humanas. O baixo grau de...
The development of an efficient transfection system in livestock cells is an important step towards investigating gene transfer and the functioning and production of transgenic animals. Important factors involved in cationic liposome mediated gene transfer were evaluated through in vitro transfection of ...
O objetivo foi estudar as mutações no PROP1 e padronizar a extração de DNA de células de swab oral, com NaCl e comparar com um kit comercial. Identificamos a mutação 301-302delAG em 6 pacientes e a mutação G51A em em um paciente. A deleção completa do PROP1 foi encontrada em dois irmãos, filh...
Turner syndrome (TS) is one of the most common human chromosomal abnormalities; it is characterized by the presence of one normal X chromosome and the complete or partial loss of the second X chromosome. The early recognition of TS patients allows for adequate therapy for short stature and pubertal sex s...
Diploid males have long been considered a curiosity contradictory to the haplo-diploid mode of sex determination in the Hymenoptera. In Apis mellifera, 'false' diploid male larvae are eliminated by worker cannibalism immediately after hatching. A 'cannibalism substance' produced by diploid drone larvae t...
As doenças cardiovasculares são a principal causa de morte nos países desnvolvidos e em desenvolvimento. Por suas elevadas incidência, prevalência e morbimortalidade e opções terapêuticas insuficientes ou, até mesmo, inficazes, tem sido crescente a busca por novos métodos terapêuticos, a fim d...
Extraction of amplifiable DNA is a frequent problem when working with degraded specimens like bone samples. The possibility of obtaining as much information as possible from these samples has a particular significance in many forensic investigations. The present investigation was aimed to assess the effi...
The spreading of knowledge depends on the access to the information and its immediate use. Models are useful to explain specific phenomena. The scientific community accepts some models in Biology after a period of time, once it has evidence to support it. The model of the structure and function of the DN...
