Results: 652

Efecto del aceite de Sacha Inchi (Plukenetia volubilis L.) en la carcinogénesis de colon inducida por 1,2–dimetilhidrazina en ratas Holtzman

Objetivos: Evaluar el efecto protector del aceite de Sacha Inchi (ASI) sobre el desarrollo de cáncer de colon (CC) inducido con 1,2–dimetilhidrazina (DMH) en ratas Holtzman. Materiales y métodos: Estudio experimental con 28 ratas albinas machos de la cepa Holtzman distribuidas al azar en 4 grupos: un ...

Frecuencia y perfil clínico de cáncer de vesícula biliar en pacientes colecistectomizados en 3 hospitales referenciales de Chiclayo entre 2011 y 2015

Objetivos: Describir la frecuencia y perfil clínico de cáncer de vesícula biliar en pacientes colecistectomizados en 3 hospitales referenciales en Chiclayo entre 2011-2015. Materiales y métodos: Estudio descriptivo transversal retrospectivo. El estudio está dividido en 2 fases, la primera consistió...

Tres cánceres primarios simultáneos: reporte de caso y revisión de la literatura

Rev. colomb. cancerol; 21 (1), 2017
Resumen La presencia de un segundo o tercer cáncer primario después del diagnóstico inicial de malignidad es un evento cada vez más frecuente asociado con la mejor sobrevida y seguimiento de pacientes con cáncer a nivel mundial. Sin embargo, la presencia de tres neoplasias primarias simultáneas sig...

Antiangiogenic VEGF165b expression in human breast MCF-7 and MCF-10A cells exposed to reverse transcriptase and protease inhibitors

Int. j. morphol; 35 (1), 2017
The combined antiretroviral therapy (cART), a multidrug combination regimen, usually consisting Nucleoside Reverse Transcriptase Inhibitors, non- Nucleoside Reverse Transcriptase Inhibitors and Protease Inhibitors has altered the morbidity pattern affecting HIV-infected individuals to include non-AIDS-de...

Rosiglitazone role in the expression of KLF6 caco-2 colon cancer cells

Int. j. morphol; 35 (1), 2017
Kruppel-like factor 6 (KLF6) is a member of the family of Kruppel transcription factors, this plays an important role in the regulation of cell growth, differentiation and angiogenesis. Rosiglitazone is a PPARy agonist drug, its antitumor effect has been described in models of breast and colon cancer. Th...

PET/MRI: a novel hybrid imaging technique. Major clinical indications and preliminary experience in Brazil

Einstein (Säo Paulo); 15 (1), 2017
ABSTRACT In recent years, medical imaging with hybrid techniques has widely accepted and employed in clinical routine. PET/MRI offers significant advantages, including excellent contrast and resolution and reduced ionizing radiation, as compared to well-established PET/CT. Therefore, PET/MRI is a promisi...

Effects of zinc supplementation on fatigue and quality of life in patients with colorectal cancer

Einstein (Säo Paulo); 15 (1), 2017
ABSTRACT Objective To investigate the effects of oral zinc supplementation on fatigue intensity and quality of life of patients during chemotherapy for colorectal cancer. Methods A prospective, randomized, double-blinded, placebo-controlled study was conducted with 24 patients on chemotherapy for col...

Cisto de colédoco associado à adenocarcinoma de vesícula biliar

Os cistos de colédoco são dilatações congênitas dos ductos biliares, que podem ser extra-hepáticos e/ou intra-hepáticos. Mais prevalentes no sexo feminino e na maioria dos casos diagnosticados até a primeira década de vida. É uma entidade pouco frequente que, quando diagnosticada na população...

Analysis of gene expression EGFR and KRAS, microRNA-21 and microRNA-203 in patients with colon and rectal cancer and correlation with clinical outcome and prognostic factors

Acta cir. bras; 32 (3), 2017
Abstract Purpose: To evaluate the expression of EGFR, KRAS genes, microRNAs-21 and 203 in colon and rectal cancer samples, correlated with their age at diagnosis, histological subtype, value of pretreatment CEA, TNM staging and clinical outcome. Methods: Expression of genes and microRNAs by real time ...