Abstract Objective: The aim of this study was to verify the association of echocardiogram, ferritin, C-reactive protein, and leukocyte count with unfavorable outcomes in pediatric sepsis. Methods: A prospective cohort study was carried out from March to December 2014, with pediatric critical care patie...
Biomarcadores/sangre,
Proteína C-Reactiva/análisis,
Ecocardiografía,
Ecocardiografía Doppler,
Ferritinas/sangre,
Ferritinas/metabolismo,
Corazón/fisiopatología,
Unidades de Cuidado Intensivo Pediátrico,
Tiempo de Internación,
Recuento de Leucocitos,
Estudios Prospectivos,
Sepsis/sangre,
Sepsis/complicaciones,
Sepsis/diagnóstico,
Sepsis/fisiopatología
Background: Galectin-3 (Gal-3) is a mediator of myocardial fibrosis involved in cardiac remodeling and a potential new prognosis marker in heart failure (HF). Aim: To measure Gal-3 at the moment of discharge in patients hospitalized for HF and its association with different variables. Material and Metho...
Galectina 3/sangre,
Insuficiencia Cardíaca/sangre,
Hospitalización,
Factores de Edad,
Biomarcadores/sangre,
Estudios Transversales,
Hipertensión/sangre,
Péptido Natriurético Encefálico/sangre,
Alta del Paciente,
Pronóstico,
Volumen Sistólico
Summary Introduction: Thrombocytopenia is commonly found in patients living in highly endemic areas for Schistosoma mansoni. Recently, different degrees of liver steatosis have also been associated with low platelet counts worldwide. We investigated the association of platelet counts with hepatosplenic ...
Biomarcadores/sangre,
Brasil/epidemiología,
Estudios Transversales,
Enfermedades Endémicas,
Hígado Graso/diagnóstico,
Hígado Graso/epidemiología,
Hígado Graso/parasitología,
Parasitosis Hepáticas/diagnóstico,
Parasitosis Hepáticas/epidemiología,
Parasitosis Hepáticas/parasitología,
Persona de Mediana Edad,
Prevalencia,
Esquistosomiasis mansoni/complicaciones,
Esquistosomiasis mansoni/diagnóstico,
Esquistosomiasis mansoni/epidemiología,
Índice de Severidad de la Enfermedad,
Trombocitopenia/diagnóstico,
Trombocitopenia/epidemiología,
Trombocitopenia/parasitología
Summary Objective: To examine the diagnostic and prognostic performances of serum procalcitonin (PCT) in adult and elderly patients with bloodstream infections (BSIs). Method: A total of 176 patients with culture-proven BSIs and 200 healthy counterparts were studied prospectively. Participants were stu...
Bacteriemia/sangre,
Biomarcadores/sangre,
Calcitonina/sangre,
Estudios de Casos y Controles,
Ensayo de Inmunoadsorción Enzimática,
Persona de Mediana Edad,
Pronóstico,
Estudios Prospectivos,
Sensibilidad y Especificidad,
Sepsis/sangre,
Sepsis/diagnóstico
ABSTRACT Background and rationale. Many different non-invasive methods have been studied with the purpose of staging liver fibrosis. The objective of this study was verifying if transient elastography is superior to aspartate aminotransferase to platelet ratio index for staging fibrosis in patients with...
Aspartato Aminotransferasas/sangre,
Pruebas Enzimáticas Clínicas/métodos,
Diagnóstico por Imagen de Elasticidad/métodos,
Hepatitis C/sangre,
Hepatitis C/diagnóstico por imagen,
Cirrosis Hepática/sangre,
Cirrosis Hepática/diagnóstico por imagen,
Recuento de Plaquetas,
Área Bajo la Curva,
Biomarcadores/sangre,
Biopsia,
Hepatitis C/virología,
Cirrosis Hepática/virología,
Oportunidad Relativa,
Valor Predictivo de las Pruebas,
Pronóstico,
Curva ROC,
Reproducibilidad de los Resultados,
Índice de Severidad de la Enfermedad
ABSTRACT Introduction. Chronic hepatitis B (CHB) is associated with high burden and healthcare costs. Virologic response achieved with antivirals is associated with progression avoidance. This study aimed to estimate the efficiency and clinical impact of antiviral strategies in CHB patients. Material a...
Costos de los Medicamentos,
Antígenos e de la Hepatitis B/sangre,
Virus de la Hepatitis B/efectos de los fármacos,
Hepatitis B Crónica/tratamiento farmacológico,
Hepatitis B Crónica/economía,
Biomarcadores/sangre,
Simulación por Computador,
Análisis Costo-Beneficio,
ADN Viral/sangre,
Progresión de la Enfermedad,
Farmacorresistencia Viral,
Quimioterapia Combinada,
Modelos Económicos,
Carga Viral
ABSTRACT Introduction and aim. Endogenous sex hormones are associated with the risk of diabetes and metabolic syndrome. Recent studies suggested the role of these hormones in nonalcoholic fatty liver disease (NAFLD). We conducted a systematic review and meta-analysis of observational studies investigati...
ABSTRACT Background. A retrospective cohort study was conducted to investigate the effect of hepatitis B surface antigen (HBsAg) level on prognosis in low viral load (< 2000 lU/mL) patients with hepatitis B-related hepatocellular carcinoma (HCC) after curative resection. Material and methods. A tota...
Carcinoma Hepatocelular/diagnóstico,
Carcinoma Hepatocelular/virología,
Carcinoma Hepatocelular/cirugía,
Hepatectomía/efectos adversos,
Antígenos de Superficie de la Hepatitis B/sangre,
Virus de la Hepatitis B/inmunología,
Hepatitis B/virología,
Hepatitis B/diagnóstico,
Hepatitis B/complicaciones,
Modelos de Riesgos Proporcionales,
Recurrencia Local de Neoplasia,
Estimación de Kaplan-Meier,
Análisis Multivariante,
Progresión de la Enfermedad,
Supervivencia sin Enfermedad,
Biomarcadores/sangre,
Estudios Retrospectivos,
Factores de Riesgo,
Factores de Tiempo,
Resultado del Tratamiento
Abstract Background: Subjects with levels of non-HDL-C 30 mg/dL above those of LDL-C (lipid discordance) or with high remnant cholesterol levels could have a greater residual cardiovascular risk. Objectives: To determine the prevalence of lipid discordance in a primary prevention population and anal...
Biomarcadores/sangre,
Enfermedades de las Arterias Carótidas/sangre,
Enfermedades de las Arterias Carótidas/diagnóstico,
Colesterol/sangre,
HDL-Colesterol/sangre,
LDL-Colesterol/sangre,
Estudios Transversales,
Placa Aterosclerótica/sangre,
Placa Aterosclerótica/diagnóstico,
Prevención Primaria,
Factores de Riesgo
Abstract Background: There is controversy whether management of blood cholesterol should be based or not on LDL-cholesterol (LDL-c) target concentrations. Objectives: To compare the estimated impact of different lipid-lowering strategies, based or not on LDL-c targets, on the risk of major cardiovascul...
