Abstract This study investigates the toxic effects of ethanol (Eth) on the reproductive system of male rats and the possible protective role of Silybum marianum seeds-infused solution (SMI) over six consecutive weeks of administration. Animals were divided into the following groups: control, SMI positive...
O neuroblastoma é um tumor sólido muito comum em crianças. O estágio mais avançado da doença é altamente agressivo e invasivo, além de pouco responsivo à terapia, que é limitada por mecanismos de resistência e reincidência relacionados à metástase. Muitos estudos tem sido feitos para identi...
La resistencia antimicrobiana es un problema de sa-lud pública mundial. Las infecciones por microorga-nismos resistentes pueden ser altamente transmisi-bles e incluso causar la muerte. Este hecho genera grandes costos para los pacientes y para los servi-cios de salud. El objetivo del presente trabajo fu...
Purpose:
To explore the neuroprotective effects of Lutongkeli (LTKL) in traumatic brain injury (TBI) and detect the related mechanism.
Methods:
TBI model was established with LTKL administration (2 and 4 g/kg/d, p.o.). Motor function of rats was examined by Rotarod test. Nissl staining was used to show ...
Purpose:
To explore the mechanism of jatrorrhizine on apoptosis and fibrosis induced by myocardial infarction (MI) in an animal model.
Methods:
The left anterior descending branch of coronary artery was surgically ligated to duplicate the mouse model of MI. The sham and infarcted mice were treated with ...
Purpose:
To evaluate the effect of preoperative intravenous chemotherapy with 5-fluorouracil on liver regeneration in an experimental model of major hepatectomy in rats.
Methods:
Wistar rats were divided into two groups of 20 animals each and submitted to 70% hepatectomy 24 h after intravenous injection...
Zhao, Dan;
Xiao, Jinli;
Qiang, Lijuan;
Deng, Xingwang;
An, Jingjing;
Zhang, Qing;
Zhao, Fang;
Ma, Jiaxiang;
Fang, Chao;
Guan, Guangyu;
Wu, Yinsheng;
Xie, Yan.
Purpose:
To investigate the active ingredients of walnut ointment (WO) and its mechanism in repairing wounds.
Methods:
The ingredients of WO were detected by gas chromatography–mass spectrometry. The effect of linoleic acid (LA) was tested by in vitro Alamar Blue (AB) reagent. Image J software, histol...
Bulhões, Apolônia Agnes Vilar de Carvalho;
Estevão, Lígia Reis de Moura;
Florencio-Silva, Rinaldo;
Simoes, Ricardo Santos;
Leite, Ana Greice Borba;
Cunha, Dayana Maria Serafim da Silva;
Ramos, Clécio Souza;
Soares, Érica Bruna de Andrade;
D’Emery, Marcela Barbosa;
Câmara, Cláudio Augusto Gomes da;
Evêncio-Neto, Joaquim.
Purpose:
To evaluate the effects of rosemary leaf essential oil-based ointments on the healing of rat skin lesions.
Methods:
Sixty adult male rats, with dorsal excisional skin wounds made surgically under anesthesia, were divided into three groups (n = 20): Sham group (untreated wounds); control group (...
Growing evidence indicates that oxidative stress plays an important role in the pathophysiology of many cardiovascular diseases, including atherosclerosis. In this context, the use of bioactive compounds with antioxidant action can bring health benefits, especially in the prevention and control of pathop...
A hidratação cutânea ocorre, em parte, pelos componentes do Fator de Hidratação Natural (NMF), originados da degradação da filagrina, sendo alguns exemplos o ácido pirrolidona-carboxílico (PCA), o ácido urocânico (UCA) e a histidina (His). Estes estão presentes no estrato córneo (EC). O obje...
