Chloroform extract (CE) and fractions obtained from Aldama arenaria roots were evaluated for their in vitro antiproliferative activity against 10 human tumor cell lines [leukemia (K-562), breast (MCF-7), ovary expressing a multidrug-resistant phenotype (NCI/ADR-RES), melanoma (UACC-62), lung (NCI-H460), ...
Plectranthus/química,
Proliferación Celular/efectos de los fármacos,
Línea Celular Tumoral/efectos de los fármacos,
Técnicas In Vitro,
Etnobotánica,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Cuba,
Diterpenos/farmacología,
Diterpenos/química,
Cloroformo
The potential use of babassu (Orbignya phalerata Mart.) in several activities is large. In view of these facts, this study aimed to determine the physicochemical composition of the babassu almond (OpAM) and evaluate the chemical, physical and physicochemical aspects of babassu coconut oil isolated by dif...
Abstract Asthma is an inflammatory disease of the lungs, and it causes oxidative stress. Lavandula dentata is an aromatic herb with anti-oxidative and anti-inflammatory activities. This study examined the activity of L. dentata extract on a guinea pig model of asthma. Adult males were divided into five ...
Abstract Medicinal plants, such as E. pyramidale, are alternatives against infections and assist in the healing process of wounds. We evaluated the effects of Hydrogel of E. pyramidale on the healing of cutaneous wounds in animal models by morphological, morphometric and histological analyses, and elucid...
Oliveira-Macêdo, L A R;
Pacheco, A G M;
Lima-Saraiva, S R G;
Silva, J C;
Oliveira-Júnior, R G;
Souza, G R;
Lavor, E M;
Silva, M G;
Ferro, J N S;
Barreto, E;
Oliveira, V R;
Almeida, J R G S.
Abstract Selaginella convoluta (Arn.) Spring is a species popularly known as "jericó", and used in folk medicine as analgesic and anti-inflammatory. This study aimed to investigate in mice the antinociceptive and anti-inflammatory activities of the hexane (Sc-Hex) and chloroform (Sc-CHCl3) fractions (10...
The Brazilian flora is known for its vast biodiversity; however, many species have been still little studied regarding to their chemical composition and biological potential. Thus, this study aimed to determine the antimicrobial, antioxidant and acaricidal activity of the extracts of leaves o...
Extractos Vegetales/farmacología,
Zanthoxylum,
Antiinfecciosos/farmacología,
Antioxidantes/farmacología,
Acaricidas/farmacología,
Salmonella enterica/efectos de los fármacos,
Ácaros/efectos de los fármacos,
Hojas de la Planta,
Extractos Vegetales/química,
Zanthoxylum/química,
Pruebas de Sensibilidad Microbiana
Paracetamol (PCM) overdose can cause hepatotoxicity with oxidative stress; the present study was carried out to establish the possible protective effect of olive leaves extract (OLE) on toxicity induced by paracetamol in adult male rats. Twenty four adult male rats were divided into four equal groups; co...
Acetaminofén/toxicidad,
Olea,
Estrés Oxidativo/efectos de los fármacos,
Antioxidantes/farmacología,
Oxidantes,
Extractos Vegetales/farmacología,
Enfermedad Hepática Inducida por Sustancias y Drogas/prevención & control,
Medicamentos Hepatoprotectores,
Hojas de la Planta,
Extractos Vegetales/química,
Hígado/patología,
Hepatocitos/efectos de los fármacos,
Distribución Aleatoria,
Ratas Endogámicas,
Ratas Wistar
Alegre, Patricia;
Mathias, Livia;
Lourenço, Maria Angelica;
Santos, Priscila Portugal dos;
Gonçalves, Andrea;
Fernandes, Ana Angélica;
Gaiolla, Paula Schmidt Azevedo;
Minicucci, Marcos Ferreira;
Zornoff, Leonardo;
Paiva, Sergio Alberto Rupp;
Polegato, Bertha Furlan.
Abstract Background: Euterpe oleracea Mart. (açaí) is a fruit with high antioxidant capacity and could be an adjuvant strategy to attenuate ischemia-reperfusion injury. Objective: To evaluate the influence of açaí in global ischemia-reperfusion model in rats. Methods: Wistar rats were assigned to ...
Bertoloni, Analisa Vasques;
Polizel, Daniel Montanher;
Ferraz Júnior, Marcos Vinícius de Castro;
Oliveira, Gabriela Bagio;
Miszura, Alexandre Arantes;
Barroso, José Paulo Roman;
Martins, André Storti;
Sardinha, Lairana Aline;
Limede, Arnaldo Cintra;
Ferreira, Evandro Maia;
Pires, Alexandre Vaz.
Essential oil (EO) from Brazilian red pepper leaves contains antimicrobial compounds that control Gram-positive bacteria in the rumen content, improving the efficiency of ruminal fermentation. The objectives of the present study were to evaluate the effects of the Brazilian red pepper leave...