Results: 5032

Short hairpin RNA targeting insulin-like growth factor binding protein-3 restores the bioavailability of insulin-like growth factor-1 in diabetic rats

Int. braz. j. urol; 42 (1), 2016
ABSTRACT Purpose To investigate whether intracavernosal injection of short hairpin RNA for IGFBP-3 could improve erectile function in streptozotocin-induced diabetic rats. Materials and methods After 12 weeks of IGFBP-3 short hairpin RNA injection treatment, intracavernous pressure responses to elect...

Estatura final en niños con talla baja idiopática tratados con hormona del crecimiento

Rev. chil. pediatr; 87 (1), 2016
Introducción: La talla baja idiopática (TBI) se define como talla ≤ 2 desviaciones estándar (DE) sin causa precisada. El uso de la hormona de crecimiento (GH) en TBI es controvertido y no existen resultados de talla final (TF) en pacientes chilenos. El objetivo de este trabajo es comparar la TF ...

Comparative effects of vitamin C on the effects of local anesthetics ropivacaine, bupivacaine, and lidocaine on human chondrocytes

Rev. bras. anestesiol; 66 (1), 2016
BACKGROUND: Intra-articular injections of local anesthetics are commonly used to enhance post-operative analgesia following orthopedic surgery as arthroscopic surgeries. Nevertheless, recent reports of severe complications due to the use of intra-articular local anesthetic have raised concerns. OBJECTIVE...

Enoftalmia causada por uso tópico unilateral de Bimatoprost

Rev. bras. oftalmol; 75 (1), 2016
RESUMO O autor descreve o caso de uma paciente que apresenta o olho direito com o sulco palpebral profundo e enoftalmia deste lado, tratado durante uma década com Bimatoprost tópica. Concluem que os achados clínicos são provavelmente efeitos colaterais do medicamento....

Effects of epicatechin, a crosslinking agent, on human dental pulp cells cultured in collagen scaffolds

J. appl. oral sci; 24 (1), 2016
ABSTRACT Objective The purpose of this study was to investigate the biological effects of epicatechin (ECN), a crosslinking agent, on human dental pulp cells (hDPCs) cultured in collagen scaffolds. Material and Method To evaluate the effects of ECN on the proliferation of hDPCs, cell counting was per...

Preventive effect of toothpastes with MMP inhibitors on human dentine erosion and abrasion in vitro

J. appl. oral sci; 24 (1), 2016
ABSTRACT The use of gels and mouthrinses with MMP inhibitors (chlorhexidine, and green tea extract) was shown to prevent erosive wear. The aim of this study was to analyze the protective effect of toothpastes containing MMP inhibitors on dentine loss induced by erosion in vitro. Material and Methods Fi...

Evaluation of an experimental rat model for comparative studies of bleaching agents

J. appl. oral sci; 24 (1), 2016
ABSTRACT Dental materials, in general, are tested in different animal models prior to their clinical use in humans, except for bleaching agents. Objectives To evaluate an experimental rat model for comparative studies of bleaching agents by investigating the influence of different concentrations and ap...

Impact of micronutrients supplementation on bone repair around implants: microCT and counter-torque analysis in rats

J. appl. oral sci; 24 (1), 2016
ABSTRACT The use of natural substances and micronutritional approaches has been suggested as a therapeutic alternative to benefit the bone healing associated with no side effects. Nevertheless, the influence of micronutritional interventions with therapeutic proprieties on the bone repair has yet to be i...

Corrosion behavior of zirconia in acidulated phosphate fluoride

J. appl. oral sci; 24 (1), 2016
ABSTRACT Objective The corrosion behavior of zirconia in acidulated phosphate fluoride (APF) representing acidic environments and fluoride treatments was studied. Material and Methods Zirconia rods were immersed in 1.23% and 0.123% APF solutions and maintained at 37°C for determined periods of time....

Influence of pH, bleaching agents, and acid etching on surface wear of bovine enamel

J. appl. oral sci; 24 (1), 2016
ABSTRACT Development of new materials for tooth bleaching justifies the need for studies to evaluate the changes in the enamel surface caused by different bleaching protocols. Objective The aim of this study was to evaluate the bovine dental enamel wear in function of different bleaching gel protocols,...